Current Evidence, Emerging Evidence, and Decision-Making: An Algorithm for Leaflet Modification Procedures.
AB, G., JT, D., RJ, L., E, H., KY, E.C., HO, A.C.C., O, D.B., D, D., P, F., & PT, G. (2026). Current Evidence, Emerging Evidence, and Decision-Making: An Algorithm for Leaflet Modification Procedures.. JACC. Cardiovascular interventions. https://doi.org/10.1016/j.jcin.2026.04.023
AB G, JT D, RJ L, E H, KY EC, HO ACC, et al. Current Evidence, Emerging Evidence, and Decision-Making: An Algorithm for Leaflet Modification Procedures.. JACC. Cardiovascular interventions. 2026; doi: 10.1016/j.jcin.2026.04.023
AB G, JT D, RJ L, et al. Current Evidence, Emerging Evidence, and Decision-Making: An Algorithm for Leaflet Modification Procedures.[J]. JACC. Cardiovascular interventions. 2026. DOI: 10.1016/j.jcin.2026.04.023.
@article{ab2026,
author = {Greenbaum AB and D'Angelo JT and Lederman RJ and Hebbo E and Eric Chan KY and Alston Conrad Chiu HO and De Backer O and Dvir D and Freeman P and Gleason PT},
title = {Current Evidence, Emerging Evidence, and Decision-Making: An Algorithm for Leaflet Modification Procedures.},
journal = {JACC. Cardiovascular interventions},
year = {2026},
doi = {10.1016/j.jcin.2026.04.023},
note = {PMID: 42264629},
}
TY - JOUR AU - Greenbaum AB AU - D'Angelo JT AU - Lederman RJ AU - Hebbo E AU - Eric Chan KY AU - Alston Conrad Chiu HO AU - De Backer O AU - Dvir D AU - Freeman P AU - Gleason PT TI - Current Evidence, Emerging Evidence, and Decision-Making: An Algorithm for Leaflet Modification Procedures. T2 - JACC. Cardiovascular interventions PY - 2026 DO - 10.1016/j.jcin.2026.04.023 AN - PMID:42264629 ER -
Leaflet modification is a necessary element in the armamentarium of the structural interventionalist and will remain an area of active investment in the future. Although leaflet splitting is proven, there are limitations in certain extreme cases. Although intraleaflet techniques are emerging and potentially have more broad applicability, there remain safety concerns with these techniques. The proposed systematic algorithms on aortic and mitral leaflet modification procedures can serve as a guide to structural operators when selecting the appropriate approach on the basis of anatomy, pathology, and procedural goals.