Left and Right Heart Remodelling at 1 Year After Transcatheter Versus Surgical Aortic Valve Replacement: A Speckle-Tracking Echocardiography Study.
ON, K., S, C.M., JD, T., S, A., B, W., J, K., RN, S., AW, A., CJ, D., & JD, F. (2026). Left and Right Heart Remodelling at 1 Year After Transcatheter Versus Surgical Aortic Valve Replacement: A Speckle-Tracking Echocardiography Study.. Interdisciplinary cardiovascular and thoracic surgery. https://doi.org/10.1093/icvts/ivag134
ON K, S CM, JD T, S A, B W, J K, et al. Left and Right Heart Remodelling at 1 Year After Transcatheter Versus Surgical Aortic Valve Replacement: A Speckle-Tracking Echocardiography Study.. Interdisciplinary cardiovascular and thoracic surgery. 2026; doi: 10.1093/icvts/ivag134
ON K, S CM, JD T, et al. Left and Right Heart Remodelling at 1 Year After Transcatheter Versus Surgical Aortic Valve Replacement: A Speckle-Tracking Echocardiography Study.[J]. Interdisciplinary cardiovascular and thoracic surgery. 2026. DOI: 10.1093/icvts/ivag134.
@article{on2026,
author = {Kislitsina ON and Chris Malaisrie S and Thomas JD and An S and Whippo B and Kruse J and Sweis RN and Asgar AW and Davidson CJ and Flaherty JD},
title = {Left and Right Heart Remodelling at 1 Year After Transcatheter Versus Surgical Aortic Valve Replacement: A Speckle-Tracking Echocardiography Study.},
journal = {Interdisciplinary cardiovascular and thoracic surgery},
year = {2026},
doi = {10.1093/icvts/ivag134},
note = {PMID: 42287711},
}
TY - JOUR AU - Kislitsina ON AU - Chris Malaisrie S AU - Thomas JD AU - An S AU - Whippo B AU - Kruse J AU - Sweis RN AU - Asgar AW AU - Davidson CJ AU - Flaherty JD TI - Left and Right Heart Remodelling at 1 Year After Transcatheter Versus Surgical Aortic Valve Replacement: A Speckle-Tracking Echocardiography Study. T2 - Interdisciplinary cardiovascular and thoracic surgery PY - 2026 DO - 10.1093/icvts/ivag134 AN - PMID:42287711 ER -
OBJECTIVES: Speckle-tracking echocardiography (STE) identifies subclinical myocardial dysfunction after aortic valve replacement. We compared strain-based remodelling and prognostic values after transcatheter (TAVR) vs surgical (SAVR) aortic valve replacement. METHODS: We analysed preoperative (preop) and postoperative (postop) left atrial volume index (LAVI), left ventricular (LV) global longitudinal strain (LV-GLS), right ventricular (RV) free wall strain (RV-FWS), RV global longitudinal strain (RV-GLS), and tricuspid annular plane systolic excursion (TAPSE) in 373 patients (TAVR n = 195; SAVR n = 178). Multivariable logistic regression assessed echocardiographic predictors of 1-year clinical outcomes. RESULTS: Left ventricular ejection fraction and LV-GLS remained stable in both groups. Right ventricular function deteriorated post-SAVR compared to TAVR (P < .001), with marked declines in TAPSE and RV-GLS (both P < .001). Preop LAVI predicted mortality (adjusted OR, 1.03; 95% CI, 1.02-1.05; P = .001) and atrial fibrillation (AF) recurrence (OR, 1.04; 95% CI, 1.02-1.06; P = .001). Stroke was predicted by preop RV-GLS (OR, 0.91; P = .031) and TAPSE (OR, 1.12; P = .013). Postop LAVI (OR, 1.06; P = .001), RV-FWS (OR, 1.06; P = .016), RV-GLS (OR, 1.10; P = .006), and TAPSE (OR, 0.93; P = .035) also remained significant predictors. Furthermore, postop LV-GLS was associated with mortality (OR, 1.08; P = .013) and AF recurrence (OR, 1.16; P = .001). CONCLUSIONS: Preop and postop strain parameters, particularly LAVI, LV-GLS, and RV longitudinal metrics, provide substantial prognostic value. Divergent RV remodelling patterns support integrating routine echocardiographic strain assessment for longitudinal risk stratification.