Posterior mitral leaflet hypoplasia in adults: diagnostic value of three-dimensional transoesophageal echocardiography: a case series.
Dylan, Y., Edward, D., Vivek, K., Rowena, S., Ian, A., Kuljit, S., & Gabriela, M.M. (2026). Posterior mitral leaflet hypoplasia in adults: diagnostic value of three-dimensional transoesophageal echocardiography: a case series.. Eur Heart J Case Rep. https://doi.org/10.1093/ehjcr/ytag160
Dylan Y, Edward D, Vivek K, Rowena S, Ian A, Kuljit S, et al. Posterior mitral leaflet hypoplasia in adults: diagnostic value of three-dimensional transoesophageal echocardiography: a case series.. Eur Heart J Case Rep. 2026; doi: 10.1093/ehjcr/ytag160
Dylan Y, Edward D, Vivek K, et al. Posterior mitral leaflet hypoplasia in adults: diagnostic value of three-dimensional transoesophageal echocardiography: a case series.[J]. Eur Heart J Case Rep. 2026. DOI: 10.1093/ehjcr/ytag160.
@article{dylan2026,
author = {Young Dylan and Dababneh Edward and Kulkarni Vivek and Solayar Rowena and Agahari Ian and Singh Kuljit and Matta Maria Gabriela},
title = {Posterior mitral leaflet hypoplasia in adults: diagnostic value of three-dimensional transoesophageal echocardiography: a case series.},
journal = {Eur Heart J Case Rep},
year = {2026},
doi = {10.1093/ehjcr/ytag160},
note = {PMID: 42040990},
}
TY - JOUR AU - Young Dylan AU - Dababneh Edward AU - Kulkarni Vivek AU - Solayar Rowena AU - Agahari Ian AU - Singh Kuljit AU - Matta Maria Gabriela TI - Posterior mitral leaflet hypoplasia in adults: diagnostic value of three-dimensional transoesophageal echocardiography: a case series. T2 - Eur Heart J Case Rep PY - 2026 DO - 10.1093/ehjcr/ytag160 AN - PMID:42040990 ER -
Posterior mitral leaflet (PML) hypoplasia is a rare and frequently under-recognized condition in adults, as transthoracic echocardiography (TTE) findings may be subtle. Transoesophageal echocardiography (TOE), particularly with three-dimensional (3D) imaging, is invaluable in confirming leaflet morphology and identifying associated anomalies. We describe three adult patients with PML hypoplasia confirmed by 3D TOE. Common features included rudimentary posterior leaflet, elongated anterior leaflet, and frequent association with congenital anomalies including bicuspid aortic valve and interatrial communications. Mitral regurgitation severity varied from mild to severe. Management was individualized based on symptoms and MR severity, ranging from conservative follow-up to surgical intervention. This series underscores the practical role of 3D TOE when TTE is equivocal: it defines leaflet morphology, distinguishes hypoplastic PML from rheumatic pathology, and detects associated anomalies that influence management. A pragmatic pathway is to suspect PML hypoplasia when MR lacks an obvious mechanism on TTE, proceed to targeted TOE/3D imaging, and tailor treatment to symptoms and MR severity.