https://heart.lihaiyang.com 心血管文献检索平台 - 最新收录论文 zh-CN https://heart.lihaiyang.com/?p=detail&id=184 外科主动脉瓣置换术一直是有症状重度退行性主动脉瓣狭窄患者的标准治疗方案。近年来，经导管主动脉瓣置换术在特定患者群体中已成为成熟的替代治疗方案，在三叶瓣狭窄方面有强有力的循证支持。然而，经导管主动脉瓣置换术在二叶主动脉瓣狭窄中的评估仍有限。最近，多项观察性研究证实了经导管主动脉瓣置换术在二叶主动脉瓣狭窄中的可行性和安全性，新一代器械的使用显示出令人鼓舞的结果。然而，与三叶瓣狭窄相比，二叶主动脉瓣狭窄患者中瓣周反流、永久性起搏器植入和主动脉根部损伤等手术并发症的发生率更高。本文综述了经导管主动脉瓣置换术治疗二叶主动脉瓣狭窄的临床证据，并就患者和器械选择、植入技术及进一步管理的适当标准提出了建议。 Thu, 19 Mar 2026 00:00:00 +0800 心脏瓣膜 https://doi.org/10.1161/CIRCINTERVENTIONS.125.016014 https://heart.lihaiyang.com/?p=detail&id=31 Severe aortic stenosis (AS) and mitral regurgitation (MR) are frequently undertreated and characterized by persistent sex, racial and ethnic, socioeconomic, and geographic disparities despite effective valve therapies. Whether automated electronic clinician notification (ECN) alerts improve the eval Thu, 01 Jan 2026 00:00:00 +0800 心脏瓣膜 https://doi.org/10.1016/j.jacc.2026.03.037 https://heart.lihaiyang.com/?p=detail&id=51 Transcatheter aortic valve replacement (TAVR) is an established therapy improving outcome in patients with severe aortic stenosis (AS). Cardiovascular magnetic resonance (CMR)-derived left atrioventricular coupling index (LACI) has demonstrated prognostic value, however, its prognostic utility in se Thu, 01 Jan 2026 00:00:00 +0800 心脏瓣膜 https://doi.org/10.1093/ehjimp/qyag061 https://heart.lihaiyang.com/?p=detail&id=52 Posterior mitral leaflet (PML) hypoplasia is a rare and frequently under-recognized condition in adults, as transthoracic echocardiography (TTE) findings may be subtle. Transoesophageal echocardiography (TOE), particularly with three-dimensional (3D) imaging, is invaluable in confirming leaflet morp Thu, 01 Jan 2026 00:00:00 +0800 心脏瓣膜 https://doi.org/10.1093/ehjcr/ytag160 https://heart.lihaiyang.com/?p=detail&id=87 Carcinoid heart disease (CHD) commonly affects right-sided heart valves, often leading to progressive right heart failure (RHF) and structural valve deterioration. A 30-year-old male with CHD and prior bioprosthetic tricuspid and pulmonic valve replacements presented with New York Heart Association Thu, 01 Jan 2026 00:00:00 +0800 心脏瓣膜 https://doi.org/10.1093/ehjcr/ytag220 https://heart.lihaiyang.com/?p=detail&id=10496 Congenital supravalvular aortic stenosis is a rare form of left ventricular outflow-tract obstruction, which is frequently associated with genetic disorders such as Williams-Beuren syndrome, despite spontaneous occurrence still being possible. Over the years, different surgical approaches to relieve Mon, 30 Nov -001 00:00:00 +0805 心脏瓣膜 https://doi.org/10.1510/mmcts.2026.020 https://heart.lihaiyang.com/?p=detail&id=45056 Background and Objectives: Transcatheter aortic valve replacement (TAVR) has become an established treatment for severe symptomatic aortic stenosis, and continuous technological advances have led to the development of different transcatheter heart valve (THV) systems. This study aimed to compare the Mon, 30 Nov -001 00:00:00 +0805 心脏瓣膜 https://doi.org/10.3390/medicina62071366 https://heart.lihaiyang.com/?p=detail&id=10498 BACKGROUND: Pulmonary regurgitation is a common long-term consequence after Tetralogy of Fallot (TOF) repair and often leads to right ventricular dilatation requiring pulmonary valve replacement (PVR). Redo sternotomy carries risks including cardiac injury and bleeding. Minimally invasive alternativ Mon, 30 Nov -001 00:00:00 +0805 心脏瓣膜 https://doi.org/10.1186/s13019-026-04379-0 https://heart.lihaiyang.com/?p=detail&id=45058 BACKGROUND: The optimal antithrombotic strategy after valve-in-valve (ViV) transcatheter aortic valve replacement (TAVR) for degenerated aortic bioprostheses remains undetermined, and current practice patterns in the United States are not well characterized. OBJECTIVES: The aim of this study was to Mon, 30 Nov -001 00:00:00 +0805 心脏瓣膜 https://doi.org/10.1016/j.jcin.2026.05.026 https://heart.lihaiyang.com/?p=detail&id=10500 BACKGROUND: The optimal leaflet modification strategy in redo transcatheter aortic valve replacement (TAVR) needs further refinement. OBJECTIVES: The aims of this study were to clarify the anatomical relationship between transcatheter aortic valve leaflets and related structures by assessing leaflet Mon, 30 Nov -001 00:00:00 +0805 心脏瓣膜 https://doi.org/10.1016/j.jcin.2026.04.007 https://heart.lihaiyang.com/?p=detail&id=10501 BACKGROUND: Leaflet modification (LM) techniques are of interest in redo transcatheter aortic valve replacement (TAVR). However, factors impacting the efficacy of LM are poorly understood. OBJECTIVES: The aim of this study was to investigate the effects of valve constraint, redo-TAVR sizing, flow, a Mon, 30 Nov -001 00:00:00 +0805 心脏瓣膜 https://doi.org/10.1016/j.jcin.2026.04.012 https://heart.lihaiyang.com/?p=detail&id=10506 Leaflet modification is a necessary element in the armamentarium of the structural interventionalist and will remain an area of active investment in the future. Although leaflet splitting is proven, there are limitations in certain extreme cases. Although intraleaflet techniques are emerging and pot Mon, 30 Nov -001 00:00:00 +0805 心脏瓣膜 https://doi.org/10.1016/j.jcin.2026.04.023 https://heart.lihaiyang.com/?p=detail&id=45071 BACKGROUND AND AIMS: Severe tricuspid regurgitation (TR) alters ventricular interaction and left-sided filling dynamics. However, the longitudinal effects of transcatheter tricuspid edge-to-edge repair (T-TEER) on left atrial (LA) remodelling and diastolic physiology remain poorly characterized. We Mon, 30 Nov -001 00:00:00 +0805 心脏瓣膜 https://doi.org/10.1093/eschf/xvag198 https://heart.lihaiyang.com/?p=detail&id=18450 The outflow tract (OFT) of the heart carries blood away from the heart into the great arteries. During embryogenesis, the OFT divides to form the aorta and pulmonary trunk, creating the double circulation present in mammals. Defects in this area account for one-third of all congenital heart defect c Mon, 30 Nov -001 00:00:00 +0805 心脏瓣膜 https://doi.org/10.7554/eLife.107748 https://heart.lihaiyang.com/?p=detail&id=12308 OBJECTIVES: Speckle-tracking echocardiography (STE) identifies subclinical myocardial dysfunction after aortic valve replacement. We compared strain-based remodelling and prognostic values after transcatheter (TAVR) vs surgical (SAVR) aortic valve replacement. METHODS: We analysed preoperative (preo Mon, 30 Nov -001 00:00:00 +0805 心脏瓣膜 https://doi.org/10.1093/icvts/ivag134 https://heart.lihaiyang.com/?p=detail&id=11295 BACKGROUND: Female patients with infective endocarditis (IE) are referred to surgery less often than male patients, and research on sex differences after IE surgery is inconclusive. Understanding the impact of sex can help clinicians optimize patient care. Therefore, we investigated sex-based differ Mon, 30 Nov -001 00:00:00 +0805 心脏瓣膜 https://doi.org/10.1161/JAHA.125.044997 https://heart.lihaiyang.com/?p=detail&id=23855 OBJECTIVES: To assess how perfusion interval relates to myocardial injury and whether this is modified by aortic cross-clamp (ACC) duration in minimally invasive mitral valve surgery. METHODS: We retrospectively analysed 556 patients receiving blood-enriched modified del Nido cardioplegia. The prima Mon, 30 Nov -001 00:00:00 +0805 心脏瓣膜 https://doi.org/10.1093/icvts/ivag174 https://heart.lihaiyang.com/?p=detail&id=24633 OBJECTIVES: The Ross operation achieves excellent outcomes in children and adolescents, but the influence of age at surgery and underlying pathology on long-term results remains uncertain. Evidence on autograft dilatation necessitating reintervention is also limited. This study aimed to identify pat Mon, 30 Nov -001 00:00:00 +0805 心脏瓣膜 https://doi.org/10.1093/icvts/ivag176 https://heart.lihaiyang.com/?p=detail&id=38468 Elucidating the mechanisms underlying rheumatic heart disease (RHD) accompanied by mitral annulus calcification (MAC) facilitates the identification of sensitive diagnostic biomarkers and the development of targeted therapeutic strategies. Proteomic analysis offers an approach to characterizing prot Mon, 30 Nov -001 00:00:00 +0805 心脏瓣膜 https://doi.org/10.1021/acs.analchem.6c02362 https://heart.lihaiyang.com/?p=detail&id=8517 BACKGROUND: The UFO procedure is an established surgical technique to treat extensive endocarditis of the aortic or mitral valve with involvement of the intervalvular fibrous body (IVFB). This technique can be used for radical resection of the whole infected tissue. Independently of the size of the Mon, 30 Nov -001 00:00:00 +0805 心脏瓣膜 https://doi.org/10.1186/s13019-026-04318-z https://heart.lihaiyang.com/?p=detail&id=20850 Mon, 30 Nov -001 00:00:00 +0805 心脏瓣膜 https://doi.org/10.11152/mu-4625 https://heart.lihaiyang.com/?p=detail&id=23669 BACKGROUND: Multiple grasping attempts are routinely required during mitral valve transcatheter-edge-to-edge repairs (M-TEER) to achieve optimal leaflet capture and minimize mitral regurgitation (MR). Whether extensive grasping adversely affects procedural outcomes remains unknown. AIMS: We aimed to Mon, 30 Nov -001 00:00:00 +0805 心脏瓣膜 https://doi.org/10.1016/j.ijcard.2026.134636 https://heart.lihaiyang.com/?p=detail&id=632 This study investigated the influence of leaflet geometry on the hemodynamic performance of pulmonary valved conduits and optimized leaflet trimming parameters using a design of experiments (DOE) approach combined with in vitro hydrodynamic testing. In vitro hydrodynamic experiments were performed t Mon, 30 Nov -001 00:00:00 +0805 心脏瓣膜 https://doi.org/10.1002/cnm.70185 https://heart.lihaiyang.com/?p=detail&id=4728 PURPOSE OF REVIEW: Transcatheter pulmonary valve replacement (TPVR) has transformed the management of patients with congenital heart disease (CHD) with dysfunctional pulmonary outflow tracts. Technological advancements have expanded the number of patients eligible for this minimally invasive alterna Mon, 30 Nov -001 00:00:00 +0805 心脏瓣膜 https://doi.org/10.1097/HCO.0000000000001312 https://heart.lihaiyang.com/?p=detail&id=633 There is growing interest in utilizing deep sedation with a natural airway rather than general endotracheal anesthesia (GETA) for cardiac catheterization procedures due to the presumed hemodynamic benefits and faster postprocedural recovery, although a paucity of data supports these assumptions. We Mon, 30 Nov -001 00:00:00 +0805 心脏瓣膜 https://doi.org/10.70278/AANAJ/.0000001066 https://heart.lihaiyang.com/?p=detail&id=634 INTRODUCTION: Aortic valve sclerosis (AVSc) is an active pathological process driven by extracellular matrix remodeling, consistent with a potentially reversible early stage of aortic valve disease. METHODS: In this cross-sectional study of 168 participants (29, normal aortic valve [NAV]; 98, AVSc; Mon, 30 Nov -001 00:00:00 +0805 心脏瓣膜 https://doi.org/10.3389/bjbs.2026.16540 https://heart.lihaiyang.com/?p=detail&id=38266 OBJECTIVES: Aortic valve neocuspidization, or the Ozaki procedure, is an alternative to prosthetic valve replacement. However, the association between native aortic root geometry, particularly the sinotubular junction-to-annulus ratio, and postoperative valve competence remains unclear. This study w Mon, 30 Nov -001 00:00:00 +0805 心脏瓣膜 https://doi.org/10.1093/icvts/ivag182 https://heart.lihaiyang.com/?p=detail&id=635 BACKGROUND: Tricuspid annular plane systolic excursion (TAPSE) is widely used to assess right ventricular (RV) longitudinal systolic function in pediatric echocardiography; however, its reliability is influenced by developmental physiology. OBJECTIVE: To evaluate the clinical utility, age-dependent Mon, 30 Nov -001 00:00:00 +0805 心脏瓣膜 https://doi.org/10.1111/echo.70516 https://heart.lihaiyang.com/?p=detail&id=636 BACKGROUND: Achromobacter xylosoxidans is an opportunistic, gram-negative organism that primarily affects immunocompromised individuals or those with indwelling medical devices. Although generally considered of low virulence, it has been increasingly recognized as a cause of serious infections, incl Mon, 30 Nov -001 00:00:00 +0805 心脏瓣膜 https://doi.org/10.1186/s13256-026-06153-1 https://heart.lihaiyang.com/?p=detail&id=637 Background and Objectives: Transcatheter edge-to-edge repair (TEER) has emerged as an effective treatment option for patients with severe mitral regurgitation who are at high surgical risk. However, clinical outcomes after TEER remain heterogeneous and are influenced not only by cardiac parameters b Mon, 30 Nov -001 00:00:00 +0805 心脏瓣膜 https://doi.org/10.3390/medicina62050944 https://heart.lihaiyang.com/?p=detail&id=638 Background and Objectives: Recent studies have focused on evaluating the hemodynamic results in patients undergoing transcatheter aortic valve implantation (TAVI) with small aortic annuli. There is limited data on the incidence, clinical characteristics, and mortality of prosthesis-patient mismatch Mon, 30 Nov -001 00:00:00 +0805 心脏瓣膜 https://doi.org/10.3390/medicina62050892 https://heart.lihaiyang.com/?p=detail&id=639 Background and Objectives: Previous comparisons between right anterior mini-thoracotomy (RAT) and partial upper sternotomy (PS) for aortic valve replacement (AVR) have shown similar clinical outcomes. This study aims to assess the potential in-hospital cost differences in one technique over the othe Mon, 30 Nov -001 00:00:00 +0805 心脏瓣膜 https://doi.org/10.3390/medicina62050856 https://heart.lihaiyang.com/?p=detail&id=640 Background and objectives: Valve-in-valve transcatheter aortic valve replacement (ViV TAVR) has become an established treatment for failed surgical bioprostheses in patients at high surgical risk. However, procedures performed in degenerated stentless aortic valves remain particularly challenging be Mon, 30 Nov -001 00:00:00 +0805 心脏瓣膜 https://doi.org/10.3390/medicina62050844 https://heart.lihaiyang.com/?p=detail&id=641 BACKGROUND: Coronary artery disease (CAD) is common in patients treated for structural heart disease, but its prevalence, prognostic impact, and optimal management in patients undergoing tricuspid transcatheter edge-to-edge repair (T-TEER) remain uncertain. OBJECTIVES: The aim of this study was to e Mon, 30 Nov -001 00:00:00 +0805 心脏瓣膜 https://doi.org/10.1016/j.jcin.2026.03.025 https://heart.lihaiyang.com/?p=detail&id=642 Tricuspid transcatheter edge-to-edge repair alleviates symptoms, but survival benefit remains inconsistent. The authors conducted a Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2020-compliant systematic review and meta-analysis (CRD42024600438) to identify multivariable predict Mon, 30 Nov -001 00:00:00 +0805 心脏瓣膜 https://doi.org/10.1016/j.jcin.2026.03.017 https://heart.lihaiyang.com/?p=detail&id=643 Coronary artery embolism is a relatively infrequent cause of myocardial infarction (MI). This case report presents a case of acute ST-segment elevation MI in the anterolateral wall consistent with suspected coronary embolism originating from a calcified bicuspid aortic valve. Comprehensive coronary Mon, 30 Nov -001 00:00:00 +0805 心脏瓣膜 https://doi.org/10.1136/bcr-2025-270452 https://heart.lihaiyang.com/?p=detail&id=644 Bartonella henselae is an intracellular bacterium which classically causes cat scratch disease as well as culture-negative endocarditis. We report a man in his 60s, with a mechanical aortic valve replacement who presented with a 6-month fever of unknown origin (FUO), splenomegaly and acute kidney in Mon, 30 Nov -001 00:00:00 +0805 心脏瓣膜 https://doi.org/10.1111/nep.70224 https://heart.lihaiyang.com/?p=detail&id=645 BACKGROUND: Mitral annular disjunction (MAD) is an anatomical anomaly increasingly recognized for its association with myocardial fibrosis and malignant arrhythmias. Identifying predictors of this fibrosis is crucial for risk stratification. This study aimed to define the functional and morphologica Mon, 30 Nov -001 00:00:00 +0805 心脏瓣膜 https://doi.org/10.1111/echo.70512 https://heart.lihaiyang.com/?p=detail&id=30853 OBJECTIVES: To explore the outcomes among patients treated with TAVI (transcatheter aortic valve implantation) in the COMPARE-TAVI 1 trial by age groups and sex. DESIGN: Cohort study. SETTING: Three Danish university hospitals. PARTICIPANTS: Patients treated with TAVI in the COMPARE-TAVI 1 trial (N= Mon, 30 Nov -001 00:00:00 +0805 心脏瓣膜 https://doi.org/10.1136/bmjopen-2026-121596 https://heart.lihaiyang.com/?p=detail&id=646 INTRODUCTION: The impact of coexisting left-sided valvular heart disease (VHD) on clinical outcomes following tricuspid valve edge-to-edge repair (T-TEER) for tricuspid regurgitation (TR) remains unclear, particularly under real-world conditions. To evaluate the prevalence and prognostic impact of c Mon, 30 Nov -001 00:00:00 +0805 心脏瓣膜 https://doi.org/10.1093/eschf/xvag103 https://heart.lihaiyang.com/?p=detail&id=647 BACKGROUND: Fibrocalcific aortic valve disease (FCAVD) is a progressive and multifactorial pathology that remains asymptomatic in its early stages and lacks effective pharmacological therapies. Aortic valve sclerosis (AVSc), the initial phase of FCAVD, is marked by leaflet thickening and early calci Mon, 30 Nov -001 00:00:00 +0805 心脏瓣膜 https://doi.org/10.7150/ijbs.125469 https://heart.lihaiyang.com/?p=detail&id=17073 BACKGROUND: Coronary obstruction is a critical risk in valve-in-valve transcatheter aortic valve replacement (TAVR). The UNICORN (undermining iatrogenic coronary obstruction with radiofrequency needle) technique mitigates this risk via intraleaflet valve deployment. However, comprehensive bench test Mon, 30 Nov -001 00:00:00 +0805 心脏瓣膜 https://doi.org/10.1016/j.jcin.2026.04.034 https://heart.lihaiyang.com/?p=detail&id=7112 Cryopreserved human heart valves and cardiovascular tissues (homografts) are essential for the surgical treatment of congenital and acquired valvular diseases, particularly in pediatric patients, where prosthetic options are limited. To address the clinical demand for high-quality grafts in Israel, Mon, 30 Nov -001 00:00:00 +0805 心脏瓣膜 https://doi.org/10.1007/s10561-026-10230-6 https://heart.lihaiyang.com/?p=detail&id=7113 As the number of mitral valve transcatheter edge-to-edge repair procedures increases, there are catheter operators and interventional echocardiography operators performing these procedures with variable expertise. Expert imaging is paramount for the success of these procedures and requires knowledge Mon, 30 Nov -001 00:00:00 +0805 心脏瓣膜 https://doi.org/10.1016/j.echo.2026.03.003 https://heart.lihaiyang.com/?p=detail&id=7115 Calcific aortic valve disease is common in older adults and a major cause of aortic stenosis. Despite its clinical impact, there are still no effective drugs that slow disease progression, and treatment largely relies on surgical or transcatheter valve replacement once stenosis becomes severe and sy Mon, 30 Nov -001 00:00:00 +0805 心脏瓣膜 https://doi.org/10.1096/fj.202600597R https://heart.lihaiyang.com/?p=detail&id=50659 BACKGROUND: Long-term outcomes remain heterogeneous for patients with discrete membranous subaortic stenosis who underwent surgical repair. We aim to develop and validate an extended risk model for predicting secondary surgery following repair of discrete membranous subaortic stenosis in pediatric p Mon, 30 Nov -001 00:00:00 +0805 心脏瓣膜 https://doi.org/10.1161/JAHA.125.049007 https://heart.lihaiyang.com/?p=detail&id=16870 BACKGROUND: Leaflet modification (LM) techniques, including electrosurgical and mechanical BASILICA (bioprosthetic or native aortic scallop intentional laceration to prevent iatrogenic coronary artery obstruction) and intraleaflet deployment, are important in the lifetime management of aortic valve Mon, 30 Nov -001 00:00:00 +0805 心脏瓣膜 https://doi.org/10.1016/j.jcin.2026.05.005 https://heart.lihaiyang.com/?p=detail&id=50662 BACKGROUND: Systemic inflammation is increasingly recognized as an important contributor to cardiovascular outcomes. High-sensitivity CRP (C-reactive protein) is an established biomarker, but its prognostic value after mitral transcatheter edge-to-edge repair remains unclear. Clinical parameters suc Mon, 30 Nov -001 00:00:00 +0805 心脏瓣膜 https://doi.org/10.1161/JAHA.125.048726 https://heart.lihaiyang.com/?p=detail&id=16872 BACKGROUND: BATMAN (balloon-assisted translocation of the mitral anterior leaflet) is an increasingly adopted technique to modify the anterior mitral leaflet (AML) and prevent left ventricular outflow tract (LVOT) obstruction during transcatheter mitral valve replacement (TMVR). OBJECTIVES: The aim Mon, 30 Nov -001 00:00:00 +0805 心脏瓣膜 https://doi.org/10.1016/j.jcin.2026.04.013 https://heart.lihaiyang.com/?p=detail&id=16873 Failure of tricuspid transcatheter edge-to-edge repair (T-TEER) with persistent severe tricuspid regurgitation (TR) is an increasingly encountered clinical scenario in contemporary structural heart disease treatment. In this setting, transcatheter tricuspid valve replacement (TTVR) is emerging as an Mon, 30 Nov -001 00:00:00 +0805 心脏瓣膜 https://doi.org/10.1016/j.jcin.2026.04.032