https://heart.lihaiyang.com 心血管文献检索平台 - 最新收录论文 zh-CN https://heart.lihaiyang.com/?p=detail&id=8 Preventive imaging for cardiothoracic risk is fragmented across separate pathways. Photon-counting CT (PCCT) may consolidate coronary, aortic-carotid, and pulmonary assessment into a single session while maintaining diagnostic performance and controlling dose. ACTA is an ongoing, general-practitione Thu, 01 Jan 2026 00:00:00 +0800 心血管 https://doi.org/10.1093/ehjimp/qyag074 https://heart.lihaiyang.com/?p=detail&id=10 Thu, 01 Jan 2026 00:00:00 +0800 心血管 https://doi.org/10.1093/eurheartj/ehag251 https://heart.lihaiyang.com/?p=detail&id=11 The paucity of data to guide selection of specific vasoactive agents in patients with cardiogenic shock (CS) may lead to variability in practice patterns. The level of variability and specific factors that are associated with the use of vasoactive medications and inodilators have not been previously Thu, 01 Jan 2026 00:00:00 +0800 心血管 https://doi.org/10.1161/CIRCHEARTFAILURE.125.013778 https://heart.lihaiyang.com/?p=detail&id=12 Early detection of risk of heart failure with reduced ejection fraction remains challenging in resource-limited settings due to limited access to echocardiography. Artificial intelligence electrocardiogram (AI-ECG) algorithms have demonstrated promise for identifying left ventricular systolic dysfun Thu, 01 Jan 2026 00:00:00 +0800 心血管 https://doi.org/10.1001/jamacardio.2026.0908 https://heart.lihaiyang.com/?p=detail&id=13 There is a lack of long-term outcome data supporting the role of nurses in cardiovascular (CV) risk management. The ALLEPRE [ALLiance for sEcondary PREvention after an acute coronary syndrome (ACS)] trial was a pragmatic, randomized, multicentre, interventional trial comparing the efficacy of a nurs Thu, 01 Jan 2026 00:00:00 +0800 心血管 https://doi.org/10.1093/eurheartj/ehag255 https://heart.lihaiyang.com/?p=detail&id=14 Pediatric patients with heart failure increasingly rely on ventricular assist devices as a bridge to transplantation. The Berlin Heart EXCOR Pediatric is the only durable ventricular assist device specifically approved for infants and small children, but its IKUS driver limits mobility and quality o Thu, 01 Jan 2026 00:00:00 +0800 心血管 https://doi.org/10.1016/j.jacc.2026.03.080 https://heart.lihaiyang.com/?p=detail&id=16 Artificial intelligence (AI) models can now detect patterns of structural heart diseases (SHDs) from electrocardiograms (ECGs), though scaling them requires the broader use of 1-lead ECGs that are now ubiquitous in wearable and portable devices. However, model development for these devices is limite Thu, 01 Jan 2026 00:00:00 +0800 心血管 https://doi.org/10.1093/ehjdh/ztag049 https://heart.lihaiyang.com/?p=detail&id=17 Rheumatic heart disease (RHD) remains the most prevalent acquired cardiovascular disease among young adults in developing countries, and there is a critical need for an efficient, affordable, and available screening strategy to detect RHD in these resource-limited areas. The 12-lead electrocardiogra Thu, 01 Jan 2026 00:00:00 +0800 心血管 https://doi.org/10.1093/ehjdh/ztag056 https://heart.lihaiyang.com/?p=detail&id=18 Thu, 01 Jan 2026 00:00:00 +0800 心血管 https://doi.org/10.1093/ehjimp/qyag053 https://heart.lihaiyang.com/?p=detail&id=19 Thu, 01 Jan 2026 00:00:00 +0800 心血管 https://doi.org/10.1093/ehjqcco/qcag077 https://heart.lihaiyang.com/?p=detail&id=20 Familial hypercholesterolaemia (FH) is an inherited lipid disorder characterized by elevated low-density lipoprotein cholesterol (LDL-C) levels and increased risk of atherosclerotic cardiovascular disease. Despite its high prevalence, FH remains underdiagnosed and undertreated in many regions, parti Thu, 01 Jan 2026 00:00:00 +0800 心血管 https://doi.org/10.1093/ehjcr/ytag264 https://heart.lihaiyang.com/?p=detail&id=21 Bias in clinical research affects not only the internal validity of studies but also the equitable distribution of health benefits derived from studies. Among the most impactful forms are selection bias, attrition bias, and algorithmic bias, each of which is capable of distorting participant represe Thu, 01 Jan 2026 00:00:00 +0800 心血管 https://doi.org/10.1161/HCG.0000000000000101 https://heart.lihaiyang.com/?p=detail&id=24 Thu, 01 Jan 2026 00:00:00 +0800 心血管 https://doi.org/10.1161/CIRCRESAHA.125.328179 https://heart.lihaiyang.com/?p=detail&id=25 Transvenous lead extraction (TLE) is the gold-standard treatment for cardiac implantable electronic device removal but carries a small risk of major complications, including superior vena cava (SVC) injury. The prompt use of endovascular occlusion devices can provide temporary haemostasis and haemod Thu, 01 Jan 2026 00:00:00 +0800 心血管 https://doi.org/10.1093/ehjcr/ytag252 https://heart.lihaiyang.com/?p=detail&id=26 Thu, 01 Jan 2026 00:00:00 +0800 心血管 https://doi.org/10.1161/CIRCIMAGING.126.019868 https://heart.lihaiyang.com/?p=detail&id=27 Purkinje fibers are established triggers of ventricular fibrillation (VF). In structural heart disease, septal fibrosis and border-zone remodeling may alter Purkinje electrograms at VF-triggering sites; however, classical electrogram criteria derived from structurally normal hearts have not been val Thu, 01 Jan 2026 00:00:00 +0800 心血管 https://doi.org/10.1016/j.hrthm.2026.04.037 https://heart.lihaiyang.com/?p=detail&id=29 The role of coronary CT angiography (CCTA) in improving outcomes among patients undergoing percutaneous coronary intervention (PCI) for obstructive coronary artery disease (CAD) remains unclear. A retrospective cohort study using the TriNetX U.S. Research Network identified adults (≥18 years) who un Thu, 01 Jan 2026 00:00:00 +0800 心血管 https://doi.org/10.1093/ehjimp/qyag062 https://heart.lihaiyang.com/?p=detail&id=30 Thu, 01 Jan 2026 00:00:00 +0800 心血管 https://doi.org/10.1093/ehjimp/qyag063 https://heart.lihaiyang.com/?p=detail&id=32 The United States is facing a growing health care affordability crisis. In 2024, national health expenditures totalled $5.3 trillion, or $15 474 per person, accounting for 18.0% of the U.S. economy. Spending on health care continues to rise, propelled by high prices for services, drugs, and devices; Thu, 01 Jan 2026 00:00:00 +0800 心血管 https://doi.org/10.1161/CIR.0000000000001442 https://heart.lihaiyang.com/?p=detail&id=33 Although ambulatory ECG (AECG) monitoring has been assessed after transcatheter aortic valve replacement (TAVR), its impact on life-threatening cardiovascular events remains unclear. This study aimed to evaluate whether systematic AECG monitoring after TAVR reduces life-threatening cardiovascular ev Thu, 01 Jan 2026 00:00:00 +0800 心血管 https://doi.org/10.1161/CIRCINTERVENTIONS.125.016288 https://heart.lihaiyang.com/?p=detail&id=35 Cardiovascular screening has been shown to reduce mortality in trials involving men. This study evaluated the effect of cardiovascular screening in both sexes, with all-cause mortality as the primary outcome. The Viborg Screening Program, a prospective, population-based study in Denmark, in which th Thu, 01 Jan 2026 00:00:00 +0800 心血管 https://doi.org/10.1093/eurheartj/ehag309 https://heart.lihaiyang.com/?p=detail&id=36 Carotid atherosclerosis is a risk factor for stroke and major adverse cardiovascular events (MACE) and is characterized by inflammation and calcification at different stages. Simultaneous assessment of both features may improve risk stratification. We therefore evaluated whether combined assessment Thu, 01 Jan 2026 00:00:00 +0800 心血管 https://doi.org/10.1093/ehjci/jeag110 https://heart.lihaiyang.com/?p=detail&id=37 Thu, 01 Jan 2026 00:00:00 +0800 心血管 https://doi.org/10.1093/ehjci/jeag109 https://heart.lihaiyang.com/?p=detail&id=38 Mineralocorticoid receptor antagonists (MRAs) are recommended as part of guideline-directed medical therapy for heart failure with reduced ejection fraction (HFrEF). The comparative effectiveness of spironolactone and eplerenone, however, remains uncertain. This was a non-interventional database stu Thu, 01 Jan 2026 00:00:00 +0800 心血管 https://doi.org/10.1093/ehjcvp/pvag030 https://heart.lihaiyang.com/?p=detail&id=41 Thu, 01 Jan 2026 00:00:00 +0800 心血管 https://doi.org/10.1016/j.jacc.2026.02.5100 https://heart.lihaiyang.com/?p=detail&id=42 Thu, 01 Jan 2026 00:00:00 +0800 心血管 https://doi.org/10.1016/j.jacc.2026.02.5117 https://heart.lihaiyang.com/?p=detail&id=43 Polygenic risk scores (PRS) stratify inherited cardiovascular risk, but their path to clinical implementation remains unclear. We aimed to develop and validate integrated PRS for 8 cardiovascular conditions and outline a framework for their clinical reporting. We analyzed genotype and clinical data Thu, 01 Jan 2026 00:00:00 +0800 心血管 https://doi.org/10.1016/j.jacc.2026.03.035 https://heart.lihaiyang.com/?p=detail&id=44 Thu, 01 Jan 2026 00:00:00 +0800 心血管 https://doi.org/10.1016/j.jacc.2026.02.5127 https://heart.lihaiyang.com/?p=detail&id=47 Thu, 01 Jan 2026 00:00:00 +0800 心血管 https://doi.org/10.1093/ehjci/jeag031 https://heart.lihaiyang.com/?p=detail&id=48 Thu, 01 Jan 2026 00:00:00 +0800 心血管 https://doi.org/10.1161/CIRCULATIONAHA.126.080040 https://heart.lihaiyang.com/?p=detail&id=49 Micro(nano)plastics (MNPs) are pervasive environmental contaminants, yet their presence in human cardiac tissue and their potential contribution to myocardial fibrosis remain unclear. We investigated whether myocardial MNP burden is associated with fibrosis severity in patients and evaluated mechani Thu, 01 Jan 2026 00:00:00 +0800 心血管 https://doi.org/10.1161/CIRCRESAHA.125.327073 https://heart.lihaiyang.com/?p=detail&id=54 Congenital heart disease (CHD) is a leading cause of pediatric morbidity and mortality worldwide. The genetics of CHD in African populations is not well understood, although it has been shown in other settings that a genetic diagnosis can have implications for patient management and risk stratificat Thu, 01 Jan 2026 00:00:00 +0800 心血管 https://doi.org/10.1161/CIRCGEN.125.005463 https://heart.lihaiyang.com/?p=detail&id=55 Thu, 01 Jan 2026 00:00:00 +0800 心血管 https://doi.org/10.1016/j.jchf.2026.103065 https://heart.lihaiyang.com/?p=detail&id=56 The "2026 HRS Expert Consensus Statement Update on Cardiovascular Implantable Electronic Device Lead Management and Extraction" provides updated recommendations to guide clinicians in the management of cardiovascular implantable electronic device (CIED) leads. Since the publication of the "2017 HRS Thu, 01 Jan 2026 00:00:00 +0800 心血管 https://doi.org/10.1016/j.hrthm.2026.04.015 https://heart.lihaiyang.com/?p=detail&id=58 Thu, 01 Jan 2026 00:00:00 +0800 心血管 https://doi.org/10.1093/ehjcvp/pvag029 https://heart.lihaiyang.com/?p=detail&id=60 Early detection of cancer and advances in treatment have significantly improved the survival rate of patients with cancer. Both cancer and its treatment can accelerate the onset of cardiovascular disease, adversely affecting prognosis of patients with cancer and survivors. Coronary (CAD) and periphe Thu, 01 Jan 2026 00:00:00 +0800 心血管 https://doi.org/10.1093/ehjci/jeag103 https://heart.lihaiyang.com/?p=detail&id=63 SGLT2 (sodium-glucose cotransporter-2) inhibitors and GLP-1R (glucagon-like peptide-1 receptor) agonists reduce the risk of major adverse cardiovascular and kidney events in individuals with various cardiometabolic conditions. The long-term efficacy and safety of these therapies, especially in low- Thu, 01 Jan 2026 00:00:00 +0800 心血管 https://doi.org/10.1161/CIRCGEN.125.005535 https://heart.lihaiyang.com/?p=detail&id=66 Lead dwell time (DT) is associated with increased complexity of cardiac implantable electronic device (CIED) extraction. Optimal strategies for risk mitigation are not well studied. Evaluate the role of intravascular lithotripsy (IVL) in extraction of leads with DT ≥10 years. We conducted a retrospe Thu, 01 Jan 2026 00:00:00 +0800 心血管 https://doi.org/10.1016/j.hrthm.2026.04.025 https://heart.lihaiyang.com/?p=detail&id=69 Physical activity (PA) is essential for the cardiovascular, emotional, and social health of all children and adolescents. However, for pediatric patients with cardiomyopathy, decades of risk-averse clinical guidance have resulted in widespread PA restriction due to fears of sudden cardiac death and Thu, 01 Jan 2026 00:00:00 +0800 心血管 https://doi.org/10.1161/CIR.0000000000001431 https://heart.lihaiyang.com/?p=detail&id=70 Aging is the major risk factor for cardiovascular disease, the leading cause of death worldwide. Research on age-related cardiac pathologies has predominantly centered on the left ventricle; however, the atria have been relatively underexplored. This oversight is noteworthy given that atrial dysfunc Thu, 01 Jan 2026 00:00:00 +0800 心血管 https://doi.org/10.1093/cvr/cvag081 https://heart.lihaiyang.com/?p=detail&id=72 Maternal autoimmune diseases (AIDs) have been linked to adverse birth outcomes that may potentially increase cardiovascular disease (CVD) risk in offspring. However, whether maternal AIDs is associated with offspring CVD remains largely unexplored. This study aimed to examine whether intrauterine ex Thu, 01 Jan 2026 00:00:00 +0800 心血管 https://doi.org/10.1093/eurheartj/ehag316 https://heart.lihaiyang.com/?p=detail&id=74 Many adults fail to achieve guideline-directed low-density lipoprotein cholesterol (LDL-C) goals on statin monotherapy, requiring additional nonstatin lipid-lowering medication. Enlicitide, an oral proprotein convertase subtilisin/kexin 9 (PCSK9) inhibitor, lowered LDL-C by 60% compared with placebo Thu, 01 Jan 2026 00:00:00 +0800 心血管 https://doi.org/10.1016/j.jacc.2026.03.036 https://heart.lihaiyang.com/?p=detail&id=76 Higher cardiorespiratory fitness (CRF) is associated with a lower risk for chronic disease and death, but its relation to healthy aging more broadly remains understudied. The aim of this study was to examine the associations between midlife CRF and later life health span (years without major chronic Thu, 01 Jan 2026 00:00:00 +0800 心血管 https://doi.org/10.1016/j.jacc.2026.02.5122 https://heart.lihaiyang.com/?p=detail&id=78 Myocarditis is an inflammatory disease involving the heart muscle and potentially the pericardium. While there are many potential causative agents, commonly grouped into infectious (viral, bacterial, parasitic) or noninfectious (autoimmune, systemic disorders, drugs, cancer related), the main pathol Thu, 01 Jan 2026 00:00:00 +0800 心血管 https://doi.org/10.1161/CIRCIMAGING.125.018547 https://heart.lihaiyang.com/?p=detail&id=79 Thu, 01 Jan 2026 00:00:00 +0800 心血管 https://doi.org/10.1161/CIRCGEN.125.005659 https://heart.lihaiyang.com/?p=detail&id=80 Eosinophilic myocarditis (EM) is a rare inflammatory heart disease often associated with eosinophilic granulomatosis with polyangiitis or hypereosinophilic syndrome. While anti-IL-5/5R and anti-IL-4/13 monoclonal antibodies (mAbs) efficacy in systemic eosinophilic diseases is established, data on EM Thu, 01 Jan 2026 00:00:00 +0800 心血管 https://doi.org/10.1093/ehjcvp/pvag025 https://heart.lihaiyang.com/?p=detail&id=88 Sinus of Valsalva aneurysm (SVA) is a rare but clinically significant cardiac anomaly, arising congenitally or through acquired causes. Typically, asymptomatic until rupture, this condition can precipitate acute or subacute heart failure via a pathological left-to-right shunt. While surgical repair Thu, 01 Jan 2026 00:00:00 +0800 心血管 https://doi.org/10.1093/ehjcr/ytag130 https://heart.lihaiyang.com/?p=detail&id=89 Acute chest pain and troponin changes in middle-aged individuals can pose a diagnostic challenge, as age-related vascular changes may complicate common inflammatory and infectious conditions, affecting outcomes. Nevertheless, research on vaccine-related myocardial injury and systemic inflammation ca Thu, 01 Jan 2026 00:00:00 +0800 心血管 https://doi.org/10.1093/ehjcr/ytaf566 https://heart.lihaiyang.com/?p=detail&id=92 This letter provides a critical analysis of the recent study by Luxán et al. (Cardiovasc Res. 2025) on the role of non-glycanated decorin in cardiac ageing. While acknowledging the importance of their findings, we identify several key areas requiring further investigation. These include: (1) the pre Thu, 01 Jan 2026 00:00:00 +0800 心血管 https://doi.org/10.1093/cvr/cvag074 https://heart.lihaiyang.com/?p=detail&id=93 Cardiac fibrosis remains a significant and currently untreatable contributor to mortality in chronic heart disease. This study aimed to comprehensively map cell-specific pathological changes in fibrotic heart tissue from aortic stenosis patients using single-nucleus RNA sequencing (snRNA-seq). We sp Thu, 01 Jan 2026 00:00:00 +0800 心血管 https://doi.org/10.1093/cvr/cvag050