https://heart.lihaiyang.com 心血管文献检索平台 - 最新收录论文 zh-CN https://heart.lihaiyang.com/?p=detail&id=188 Stressor-associated atrial fibrillation (AF) refers to new-onset AF that occurs with a reversible, acute stressor. Identifying individuals at highest risk for AF recurrence is essential to guide management. Although clinical factors have shown limited value, the utility of contemporary artificial in Fri, 20 Mar 2026 00:00:00 +0800 房颤 https://doi.org/10.1161/JAHA.125.047146 https://heart.lihaiyang.com/?p=detail&id=177 We investigated the role of Lgi3-4 proteins in cardiac electrophysiology, with a specific focus on IKur, and their potential contribution to the pathophysiology of atrial fibrillation (AF). In human atrial tissue and heterologous cells, Lgi3 and Lgi4 interacted with KV1.5 channels. In a mouse model Thu, 19 Mar 2026 00:00:00 +0800 房颤 https://doi.org/10.1093/cvr/cvag049 https://heart.lihaiyang.com/?p=detail&id=176 Catheter-based closure of the left atrial appendage is an alternative to oral anticoagulation for stroke prevention in patients with atrial fibrillation. The effectiveness of this strategy, as compared with physician-directed best medical care, in patients at high risk for stroke and bleeding is unk Wed, 18 Mar 2026 00:00:00 +0800 房颤 https://doi.org/10.1056/NEJMoa2513310 https://heart.lihaiyang.com/?p=detail&id=28688 BACKGROUND: Atrial fibrillation is a leading cause of emergency medical services (EMS) use, but sex differences across prehospital, hospital, and postdischarge care remain poorly characterized. METHODS: We performed a population-based linked cohort study of adults attended by EMS for atrial fibrilla Mon, 30 Nov -001 00:00:00 +0805 房颤 https://doi.org/10.1161/JAHA.125.046016 https://heart.lihaiyang.com/?p=detail&id=10529 BACKGROUND: Older adults treated with anticoagulants for atrial fibrillation (AF) or venous thromboembolism (VTE) face heightened bleeding risk, which can affect physical, emotional and social wellbeing and function. Existing instruments assess treatment satisfaction or generic quality of life but d Mon, 30 Nov -001 00:00:00 +0805 房颤 https://doi.org/10.1016/j.thromres.2026.109726 https://heart.lihaiyang.com/?p=detail&id=11328 Atrial fibrillation is the most prevalent sustained cardiac arrhythmia, characterized by limited therapeutic options because of incompletely understood mechanisms of its development. The key underlying pathogenetic mechanisms involve atrial myocardial inflammation and fibrosis in response to pressur Mon, 30 Nov -001 00:00:00 +0805 房颤 https://doi.org/10.1161/JAHA.125.048418 https://heart.lihaiyang.com/?p=detail&id=11329 BACKGROUND: Bepridil is an antiarrhythmic drug used to treat paroxysmal atrial fibrillation; however, its use is limited by corrected QT interval (QTc) prolongation and the risk of ventricular arrhythmias. This study aimed to identify genetic variants associated with bepridil-associated QTc prolonga Mon, 30 Nov -001 00:00:00 +0805 房颤 https://doi.org/10.1161/JAHA.125.047046 https://heart.lihaiyang.com/?p=detail&id=1861 BACKGROUND: Patients with Cushing's syndrome (CS) have a high prevalence of cardiovascular disease, and other recognized risk factors for atrial fibrillation/flutter (AF/AFL); however, the prevalence of AF/AFL has not been well characterized in this population. METHODS: We conducted a retrospective Mon, 30 Nov -001 00:00:00 +0805 房颤 https://doi.org/10.1093/ejendo/lvag094 https://heart.lihaiyang.com/?p=detail&id=659 Background and Objectives: Elective electrical cardioversion (eECV) in patients with atrial fibrillation (AF) or atrial flutter is associated with a low risk of thromboembolic events (TEs) when adequate anticoagulation is provided. However, the role of routine transesophageal echocardiography (TEE) Mon, 30 Nov -001 00:00:00 +0805 房颤 https://doi.org/10.3390/medicina62050970 https://heart.lihaiyang.com/?p=detail&id=660 Background and Objectives: Atrial fibrillation (AF) is the most common cardiac arrhythmia, present in up to 14-20% of patients undergoing cardiac surgery, with the number of patients expected to double within the next decade. Despite a Class I recommendation for concomitant surgical ablation and a C Mon, 30 Nov -001 00:00:00 +0805 房颤 https://doi.org/10.3390/medicina62050890 https://heart.lihaiyang.com/?p=detail&id=661 Background and Objectives: Diazepam, a GABAA receptor agonist with sympatholytic properties, is sometimes co-administered with antiarrhythmic agents in the emergency management of atrial fibrillation (AF), yet evidence supporting this practice is remarkably limited. Given the established role of sym Mon, 30 Nov -001 00:00:00 +0805 房颤 https://doi.org/10.3390/medicina62050861 https://heart.lihaiyang.com/?p=detail&id=662 Atrial fibrillation (AF) and heart failure (HF) synergistically interact to exacerbate each other. However, treatment of one entity can greatly improve management of the other. Although historically, permissive medical therapy was the mainstay of AF management in the HF population, recent data stron Mon, 30 Nov -001 00:00:00 +0805 房颤 https://doi.org/10.1016/j.ccep.2026.03.001 https://heart.lihaiyang.com/?p=detail&id=663 IMPORTANCE: It is unclear whether the beneficial effects of nonsteroidal anti-inflammatory drugs (NSAIDs) that selectively inhibit cyclooxygenase 2 (COX-2) in decreasing the risk of gastrointestinal (GI) bleeding are retained in patients with nonvalvular atrial fibrillation (NVAF) concomitantly trea Mon, 30 Nov -001 00:00:00 +0805 房颤 https://doi.org/10.1001/jamanetworkopen.2026.13941 https://heart.lihaiyang.com/?p=detail&id=664 The oblique vein of the left atrium (Vein of Marshall) is frequently underemphasized in anatomical education and classical texts, often regarded as a minor or vestigial structure. However, contemporary electrophysiological practice has revealed its significant role in the pathophysiology and ablatio Mon, 30 Nov -001 00:00:00 +0805 房颤 https://doi.org/10.1007/s00276-026-03903-0 https://heart.lihaiyang.com/?p=detail&id=665 BACKGROUND: Prior analyses of trials comparing direct oral anticoagulants (DOACs) to warfarin in atrial fibrillation (AF) have not routinely incorporated patient preferences, despite substantial variation in how patients value the trade-off between outcomes such as stroke and bleeding. By applying p Mon, 30 Nov -001 00:00:00 +0805 房颤 https://doi.org/10.1056/EVIDoa2500323 https://heart.lihaiyang.com/?p=detail&id=666 Atrial fibrillation (AF) is a prevalent cardiac arrhythmia associated with an elevated risk of severe complications, including stroke and heart failure. Due to its paroxysmal nature and the inherent complexity of electrocardiogram (ECG) signals, developing highly accurate and robust automated detect Mon, 30 Nov -001 00:00:00 +0805 房颤 https://doi.org/10.3390/bios16050275 https://heart.lihaiyang.com/?p=detail&id=667 BACKGROUND: Frailty significantly increases the risk of adverse outcomes in patients with atrial fibrillation (AF), particularly among middle-aged and elderly individuals. Despite its clinical importance, there is a lack of efficient, multidimensional identification tools specifically tailored for t Mon, 30 Nov -001 00:00:00 +0805 房颤 https://doi.org/10.2147/CIA.S593644 https://heart.lihaiyang.com/?p=detail&id=22688 AIMS: Cryoballoon pulmonary vein isolation (CB-PVI) has become an established treatment for atrial fibrillation and, recently, it has been proposed as first-line therapy for the treatment of paroxysmal atrial fibrillation. Nevertheless, some concerns remain regarding the safety of this thermal energ Mon, 30 Nov -001 00:00:00 +0805 房颤 https://doi.org/10.2459/JCM.0000000000001886 https://heart.lihaiyang.com/?p=detail&id=8147 AIMS: To compare glucagon-like peptide-1 receptor agonists (GLP-1RA) with sodium-glucose cotransporter-2 inhibitors (SGLT-2i) for cardiovascular, atrial fibrillation (AF) disease course, and safety outcomes in adults with concurrent AF and type 2 diabetes. METHODS: Retrospective propensity-score-mat Mon, 30 Nov -001 00:00:00 +0805 房颤 https://doi.org/10.1016/j.diabres.2026.113346 https://heart.lihaiyang.com/?p=detail&id=7143 BACKGROUND: The coexistence of persistent atrial fibrillation (AF) and heart failure with reduced left ventricular ejection fraction is associated with greater morbidity and death than either condition alone. Catheter ablation improves outcomes in selected patients, yet results in persistent AF rema Mon, 30 Nov -001 00:00:00 +0805 房颤 https://doi.org/10.1161/JAHA.125.047774 https://heart.lihaiyang.com/?p=detail&id=50684 BACKGROUND: The benefit of continuing oral anticoagulation (OAC) after catheter ablation (CA) for atrial fibrillation (AF) in patients with a high risk of stroke remains unclear. The Safeness or Threat Of Pausing-Oral anticoagulant therapy After Catheter ablation for atrial fibrillation study (STOP- Mon, 30 Nov -001 00:00:00 +0805 房颤 https://doi.org/10.1161/JAHA.126.050952 https://heart.lihaiyang.com/?p=detail&id=50687 AIMS: Pulsed field ablation (PFA) is a non-thermal energy modality for ablation of atrial fibrillation (AF). Although PFA has demonstrated an excellent overall safety profile, increasing evidence suggests an association with intravascular haemolysis, and acute kidney injury (AKI). However, the exten Mon, 30 Nov -001 00:00:00 +0805 房颤 https://doi.org/10.1093/europace/euag190