AIM: It was aimed to investigate the patients who underwent coronary artery bypass grafting with coronary endarterectomy (CABG-CE) and postoperative dual antiplatelet therapy (DAPT) in terms of acute coronary syndrome, mortality and morbidity in the early period. METHOD: Ninety-nine patients who underwent endarterectomy during CABG between 2022 and 2024 were included in the study. DAPT was applied after surgery. Preoperative and postoperative electrocardiogram (ECG), echocardiography (Echo), ejection fraction (EF) changes, operative time, postoperative first 30-day mortality, and length of stay in the intensive care unit (ICU) were investigated. RESULT: The left anterior descending (LAD) coronary artery endarterectomy rate was 38.4%. Among those who underwent LAD endarterectomy, eight had ECG changes in favour of myocardial infarction (MI), eight had postoperative arrhythmia, and two had mortality. The right coronary artery (RCA) endarterectomy rate was 38.4%. Of these cases, two had ECG changes, nine had postoperative arrhythmia, and two hadmortality. The circumflex artery (CX) endarterectomy rate was 12.1%. Of these, three had ECG changes, five had postoperative arrhythmia, and two had mortality. Although the bypass numbers were equal, the cross-clamping time was longer in patients who underwent LAD endarterectomy than in those who underwent RCA or CX endarterectomy. The postoperative blood replacement requirement was 1.6 ± 1.4 units. The mean length of stay in the ICU was 4.0 ± 4.5 days. CONCLUSIONS: DAPT is an effective treatment method after CABG-CE surgery, especially for patients with diabetes mellitus (DM) and coronary artery disease and diffuse, long-segment, calcified plaque.