[Research progress of mitochondria-associated endoplasmic reticulum membranes in sepsis-induced cardiomyopathy].

📚 期刊: Zhonghua xin xue guan bing za zhi 📅 发表: 0000-00-00 🔬 PMID: 42452930 🔗 DOI: 10.3760/cma.j.cn112148-20260319-00188 👁️ 浏览: 8

👤 作者: Yang C, Sun ZC, Xue L

心肌病

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Yang C, Sun ZC, Xue L (0000). [Research progress of mitochondria-associated endoplasmic reticulum membranes in sepsis-induced cardiomyopathy].. Zhonghua xin xue guan bing za zhi. https://doi.org/10.3760/cma.j.cn112148-20260319-00188

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📝 摘要

线粒体相关内质网膜（MAMs）是线粒体与内质网通过物理接触形成的特殊功能结构域，介导两大细胞器间的物质转运与信息交流，在空间分布与生物学功能上均实现高度偶联。脓毒症心肌病是脓毒症进程中出现的可逆性心肌功能损伤。现有研究表明MAMs可通过调控钙信号传导、自噬、线粒体动力学、内质网应激及炎症等关键通路，参与脓毒症心肌病的发生与发展。该文就MAMs的结构特征、生物学功能及其在脓毒症心肌病中的作用机制作一综述，以期为该病的防治提供潜在新靶点。.

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[Research progress of mitochondria-associated endoplasmic reticulum membranes in sepsis-induced cardiomyopathy].

📑 引用格式

🔗 分享文献

📝 摘要

📝 阅读笔记

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