Rationale and Design of CARDIO-TTRansform, a Phase 3 Trial of Eplontersen in Transthyretin Amyloid Cardiomyopathy.
Transthyretin amyloidosis with cardiomyopathy is a progressive, fatal disease characterized by deposition of extracellular misfolded transthyretin (TTR) in the myocardium. Eplontersen is an N-acetylga...
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Socioeconomic status (SES) is an established risk factor for poor cardiovascular outcomes, with atrial fibrillation (AF) a major contributor to cardiovascular morbidity and mortality. To examine assoc...
Management of dyslipidaemia in patients with comorbidities - facing the challenge: Heart failure.
The combined prevalence of heart failure (HF) with coronary atherosclerosis is frequent and often causally linked. The aim of this review is to elucidate whether lipid lowering drugs (LLDs) are useful...
基于心电图向量的机器学习模型将俯卧位心电图转换为标准心电图的建立与验证
俯卧位心电图在重症监护和特殊检查环境中经常获取，但其解读受到体位变化的显著影响，导致ST段偏移和T波改变，可能干扰STEMI等心血管疾病的诊断。本研究旨在开发一种将俯卧位心电图转换为标准心电图的方法，以方便医师诊断STEMI和其他心血管疾病。前瞻性采集了标准心电图、心电向量图（VCG）和俯卧位心电图数据，建立基于心电图向量的机器学习模型。研究使用多种机器学习算法进行建模，并通过独立数据集进行验证。...
Association between blood pressure and waist-to-height ratio in schoolchildren aged 6 to 8 years in the Valparaíso Region, Chile.
BACKGROUND: Hypertension is a serious obesity-related disease that affects the paediatric population. Objective: To examine the positive association between systolic and diastolic blood pressure and w...
Atrial tachycardias (AT) represent an increasingly recognized cause of morbidity and mortality. Over the past decade, the mechanistic understanding and therapeutic concepts guiding AT treatment have u...
The aim is to present expert-agreed guidelines for the primary prevention of cardiovasculotoxicity of anticancer therapy as part of the Cardioprotection 2025 Consensus of the Russian Society of Cardio...
Heart failure (HF) affects over 60 million individuals globally. Contemporary guideline-directed medical therapies (GDMT) reduce cardiovascular mortality and HF hospitalizations. However, medication n...
INTRODUCTION: This report presents data on implantable cardioverter-defibrillator (ICD) implants performed in Spain in 2024. METHODS: The registry is based on information submitted by centers after de...
INTRODUCTION: This report presents the results of the Spanish catheter ablation registry for 2024. METHODS: A retrospective analysis of ablation procedures performed at participating hospitals in Spai...
Electrical cardioversion (ECV) is an established and effective method for restoring sinus rhythm in patients with persistent atrial fibrillation. A position paper by the German Cardiac Society provide...
Lung ultrasonography (LUS) is a reliable and reproducible tool across various clinical settings. Its high diagnostic accuracy, portability, and real-time imaging capabilities make it especially suitab...
In the 2021 European Society of Cardiology (ESC) heart failure (HF) guidelines, sodium-glucose cotransporter 2 (SGLT2) inhibitors were recommended for the prevention of HF in patients with type 2 diab...
BACKGROUND: Cardiac positron emission tomography (PET) and single-photon emission computed tomography (SPECT) are widely used for the assessment of coronary artery disease. While SPECT remains more av...
Hypertensive acute heart failure (HT-AHF) has historically been recognized as a distinct clinical phenotype of AHF, characterized by acute pulmonary congestion in the context of elevated systolic bloo...
INTRODUCTION: This report presents data on cardiac pacing system implants in Spain during 2024. METHODS: The registry is based on data voluntarily submitted by implanting centers to the Heart Rhythm A...
Our aim is to determine the rate of unexpected malrotation identified on routine preoperative upper gastrointestinal (UGI) contrast study in infants with congenital heart disease (CHD) prior to gastro...
The purpose of this document is to provide updated, evidence-based recommendations for the prevention of cardiovascular toxicity associated with anticancer therapy (anthracyclines, HER2-targeted thera...
OBJECTIVE: To assess the prognostic impact of continuity of care (COC), defined as care provided by the same primary care physician (PCP), in patients with heart failure (HF) referred for cardiology c...
Obesity confers increased risks of HF, coronary artery disease, and stroke, and weight loss can reduce cardiovascular disease risk. Given emerging evidence of the benefits of semaglutide and tirzepati...