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[The role and mechanism of transient receptor potential M2 channel-mediated calcium homeostasis imbalance in the development of diabetic cardiomyopathy].

[The role and mechanism of transient receptor potential M2 channel-mediated calcium homeostasis imbalance in the development of diabetic cardiomyopathy].

期刊: Zhonghua xin xue guan bing za zhi 日期: 2026-06-24 PMID: 42324116 DOI: 10.3760/cma.j.cn112148-20260130-00070 浏览: 38
作者: Yang YF, Qian LL, Wang RX
YF, Y., LL, Q., & RX, W. (2026). [The role and mechanism of transient receptor potential M2 channel-mediated calcium homeostasis imbalance in the development of diabetic cardiomyopathy].. Zhonghua xin xue guan bing za zhi. https://doi.org/10.3760/cma.j.cn112148-20260130-00070
YF Y, LL Q, RX W. [The role and mechanism of transient receptor potential M2 channel-mediated calcium homeostasis imbalance in the development of diabetic cardiomyopathy].. Zhonghua xin xue guan bing za zhi. 2026; doi: 10.3760/cma.j.cn112148-20260130-00070
YF Y, LL Q, RX W. [The role and mechanism of transient receptor potential M2 channel-mediated calcium homeostasis imbalance in the development of diabetic cardiomyopathy].[J]. Zhonghua xin xue guan bing za zhi. 2026. DOI: 10.3760/cma.j.cn112148-20260130-00070.
@article{yf2026,
  author = {Yang YF and Qian LL and Wang RX},
  title = {[The role and mechanism of transient receptor potential M2 channel-mediated calcium homeostasis imbalance in the development of diabetic cardiomyopathy].},
  journal = {Zhonghua xin xue guan bing za zhi},
  year = {2026},
  doi = {10.3760/cma.j.cn112148-20260130-00070},
  note = {PMID: 42324116},
}
TY  - JOUR
AU  - Yang YF
AU  - Qian LL
AU  - Wang RX
TI  - [The role and mechanism of transient receptor potential M2 channel-mediated calcium homeostasis imbalance in the development of diabetic cardiomyopathy].
T2  - Zhonghua xin xue guan bing za zhi
PY  - 2026
DO  - 10.3760/cma.j.cn112148-20260130-00070
AN  - PMID:42324116
ER  - 

摘要

糖尿病心肌病是糖尿病患者发生心力衰竭的重要原因,而细胞内钙稳态失衡是驱动心肌损伤与心室重构的核心病理环节。瞬时受体电位M2通道作为一类具有Ca²⁺非选择性通透性的阳离子通道,是连接氧化应激与代谢紊乱的关键调控分子。该文主要介绍瞬时受体电位M2通道在糖尿病心肌病钙稳态失衡中的作用及相关分子机制,明确该通道可能成为糖尿病心肌病的潜在治疗靶点,以期为糖尿病心肌病的防治提供新的思路与方向。.

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