Sex Differences in Long-term Outcomes Following Coronary Artery Bypass Grafting: A Nationwide Population-Based Propensity Score-Matched Cohort Study.
SK, L., YH, J., YJ, K., Y, C., HJ, J., YH, C., K, S., WS, K., JB, K., & HJ, K. (2026). Sex Differences in Long-term Outcomes Following Coronary Artery Bypass Grafting: A Nationwide Population-Based Propensity Score-Matched Cohort Study.. Journal of Korean medical science. https://doi.org/10.3346/jkms.2026.41.e161
SK L, YH J, YJ K, Y C, HJ J, YH C, et al. Sex Differences in Long-term Outcomes Following Coronary Artery Bypass Grafting: A Nationwide Population-Based Propensity Score-Matched Cohort Study.. Journal of Korean medical science. 2026; doi: 10.3346/jkms.2026.41.e161
SK L, YH J, YJ K, et al. Sex Differences in Long-term Outcomes Following Coronary Artery Bypass Grafting: A Nationwide Population-Based Propensity Score-Matched Cohort Study.[J]. Journal of Korean medical science. 2026. DOI: 10.3346/jkms.2026.41.e161.
@article{sk2026,
author = {Lim SK and Jeong YH and Kim YJ and Cho Y and Jang HJ and Cho YH and Sung K and Kim WS and Kim JB and Kim HJ},
title = {Sex Differences in Long-term Outcomes Following Coronary Artery Bypass Grafting: A Nationwide Population-Based Propensity Score-Matched Cohort Study.},
journal = {Journal of Korean medical science},
year = {2026},
doi = {10.3346/jkms.2026.41.e161},
note = {PMID: 42478250},
}
TY - JOUR AU - Lim SK AU - Jeong YH AU - Kim YJ AU - Cho Y AU - Jang HJ AU - Cho YH AU - Sung K AU - Kim WS AU - Kim JB AU - Kim HJ TI - Sex Differences in Long-term Outcomes Following Coronary Artery Bypass Grafting: A Nationwide Population-Based Propensity Score-Matched Cohort Study. T2 - Journal of Korean medical science PY - 2026 DO - 10.3346/jkms.2026.41.e161 AN - PMID:42478250 ER -
BACKGROUND: The relationship between sex differences and clinical outcomes following coronary artery bypass grafting (CABG) has been highlighted in several studies. However, these studies were mostly based on single- or multi-center data, and only a few meta-analyses examined long-term outcomes. To address this limitation, we conducted a nationwide population-based cohort study in Korea. METHODS: A total of 48,206 adult patients who underwent first-time isolated CABG between January 2005 and December 2021 were enrolled. To address potential confounding, propensity score (PS) matching was conducted. The primary outcome was overall mortality. RESULTS: Among the enrolled patients, 12,270 (25.5%) were female. The median age of the overall cohort was 66.0 years (interquartile range [IQR], 59.0-72.0), with female patients (median, 69.0; IQR, 63.0-75.0) being significantly older than male patients (P < 0.001). In the PS-matched cohort, in-hospital mortality did not differ significantly between female and male groups (odds ratio, 1.13; 95% confidence interval [CI], 0.78-1.64). However, the female group was a significant predictor of better overall survival (hazard ratio [HR], 0.83; 95% CI, 0.77-0.90) compared to the male group. Cardiac-related mortality was comparable between the two groups (HR, 0.89; 95% CI, 0.65-1.22). The median duration of the follow-up period was 7.8 (IQR, 4.0-12.6) years. CONCLUSION: In this nationwide population-based PS-matched cohort study, female patients who underwent isolated CABG exhibited significantly lower overall mortality compared to male patients during long-term follow-up, whereas no significant difference was observed in cardiac-related mortality.