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Atrial fibrillation burden during in-patient cardiac monitoring after acute ischaemic stroke.

Atrial fibrillation burden during in-patient cardiac monitoring after acute ischaemic stroke.

期刊: European stroke journal 日期: 2026-07-06 PMID: 42479896 DOI: 10.1093/esj/aakag079 浏览: 25
作者: Klammer MG, Reimann L, Richter O, Lieschke S, Stengl H, Hellwig S, Schoels M, Nelde A, Villringer K, Meisel A
MG, K., L, R., O, R., S, L., H, S., S, H., M, S., A, N., K, V., & A, M. (2026). Atrial fibrillation burden during in-patient cardiac monitoring after acute ischaemic stroke.. European stroke journal. https://doi.org/10.1093/esj/aakag079
MG K, L R, O R, S L, H S, S H, et al. Atrial fibrillation burden during in-patient cardiac monitoring after acute ischaemic stroke.. European stroke journal. 2026; doi: 10.1093/esj/aakag079
MG K, L R, O R, et al. Atrial fibrillation burden during in-patient cardiac monitoring after acute ischaemic stroke.[J]. European stroke journal. 2026. DOI: 10.1093/esj/aakag079.
@article{mg2026,
  author = {Klammer MG and Reimann L and Richter O and Lieschke S and Stengl H and Hellwig S and Schoels M and Nelde A and Villringer K and Meisel A},
  title = {Atrial fibrillation burden during in-patient cardiac monitoring after acute ischaemic stroke.},
  journal = {European stroke journal},
  year = {2026},
  doi = {10.1093/esj/aakag079},
  note = {PMID: 42479896},
}
TY  - JOUR
AU  - Klammer MG
AU  - Reimann L
AU  - Richter O
AU  - Lieschke S
AU  - Stengl H
AU  - Hellwig S
AU  - Schoels M
AU  - Nelde A
AU  - Villringer K
AU  - Meisel A
TI  - Atrial fibrillation burden during in-patient cardiac monitoring after acute ischaemic stroke.
T2  - European stroke journal
PY  - 2026
DO  - 10.1093/esj/aakag079
AN  - PMID:42479896
ER  - 

摘要

BACKGROUND: Atrial fibrillation (AF) burden, the time spent in AF, is increasingly investigated. Data on its characteristics and temporal patterns during early in-hospital telemetry after ischaemic stroke remain limited. PATIENTS AND METHODS: Continuous ECG telemetry was analysed in consecutive patients with MRI-confirmed ischaemic stroke and AF admitted between October 2020 and January 2023 in this observational retrospective cohort trial. Peak AF burden within any 24-h window was categorised as low (≤1 h), medium (>1-6 h), high (> 6 h) or no recorded AF episodes. Associations with clinical and imaging features were assessed using multivariable regression. RESULTS: Among 392 patients with AF-related stroke (median monitoring duration 68 h, median AF burden 12.0 h), AF burden was low in 30 (7.7%), medium in 68 (17.3%), high in 193 (49.2%) and 101 (25.8%) had no recorded episodes. Left-insular stroke was negatively associated with high AF burden (aOR 0.38, 95% CI, 0.15-0.84, P < .05). There was a signal towards a positive association with right-insular stroke (aOR 1.75, 95% CI, 0.90-3.41, P = .09). The laterality difference persisted in continuous-scale analyses. First AF episodes clustered in the early evening among low-burden patients, with early morning episodes least common across all groups. Among patients with known stroke onset (n = 102), 49 exhibited AF confined to the first 48 h. CONCLUSION: AF burden varies widely during early in-hospital monitoring after ischaemic stroke and seems to differ according to insular lesion laterality. Our findings are hypothesis-generating and highlight the need for integrating lesion location, circadian and arrhythmia dynamics to characterise AF burden after stroke.

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