All-cause healthcare cost differences across ambulatory cardiac monitoring modalities in Medicare beneficiaries: a real-world claims-based study using entropy balancing.
OBJECTIVES: Arrhythmias, including atrial fibrillation and ventricular tachycardia, are associated with substantial morbidity and healthcare utilization in older adults. Ambulatory cardiac monitoring ...
Role of NADPH oxidase 2-derived reactive oxygen species in cardiac electrophysiological disorders.
Oxidative stress mediated by NADPH oxidase 2 (NOX2), a major source of reactive oxygen species in the myocardium, is an important mechanism that underlies cardiac arrhythmias. NOX2 is activated by the...
Completeness and interrater reliability of the Norwegian National Electrophysiology and Ablation Registry (AblaNor).
Objectives. Data quality is a prerequisite for the use of registries. National Registry for Ablation and Electrophysiology in Norway (AblaNor) is a nationwide medical quality register of Norwegian pat...
Remimazolam for sedation in flexible bronchoscopy: A systematic review and meta-analysis of randomised controlled trials.
BACKGROUND: Remimazolam is a novel benzodiazepine increasingly used for procedural sedation and general anaesthesia. Its role in clinical use in flexible bronchoscopy remains under investigation. AIM:...
Cost-effectiveness analysis of apixaban compared with other oral anticoagulants for the treatment of non-valvular atrial fibrillation in a Belgian healthcare setting.
AIMS: Direct oral anticoagulants (DOACs) are recommended for stroke and systemic embolism prevention in patients with non-valvular atrial fibrillation (NVAF) in preference to vitamin K antagonists (VK...
Effects of curcumin and nicorandil on nilotinib-induced QT interval prolongation in rats: A telemetry-based study.
BACKGROUND: Long QT syndrome (LQTS) is characterized by QT prolongation, ventricular arrhythmias and sudden death. Nilotinib (Nilo), a tyrosine kinase inhibitor used in chronic myeloid leukemia, prolo...
Partially Virtual vs In-Person Care in Cardiovascular Conditions-Time Trends, Patient Characteristics, and Medication Management: Cohort Study.
BACKGROUND: Despite growing initiatives to promote partially virtual care, there is still a lack of comprehensive data describing its use, patient characteristics, and medication management practices....
Electrocardiographic recording in horses at rest: a concordance analysis of two methods.
Cardiac arrhythmias are frequently detected during routine auscultation in athletic horses. Assessment of their clinical significance requires electrocardiography (ECG) to analyze waveforms and interv...
Anticoagulation in Advanced Chronic Kidney Disease: Navigating Uncertainty.
Advanced chronic kidney disease (CKD) is characterized by a complex hemostatic state in which thrombotic and bleeding risks coexist. As kidney function declines, balancing thrombotic protection agains...
Trends and In-Hospital Outcomes of Ventricular Tachycardia in Ischemic Versus Non-Ischemic Dilated Cardiomyopathy-An Insight From the Nationwide Readmissions Database (2016-2020).
BACKGROUND: Ventricular tachycardia (VT) is a major cause of morbidity and mortality in patients with structural heart disease, yet real-world comparisons between ischemic cardiomyopathy (ICM) and non...
Reversible High-Degree Atrioventricular Block Associated With Magnesium Toxicity in Severe Pre-Eclampsia.
We report a 35-year-old woman at 31 weeks and 5 days' gestation with severe pre-eclampsia and acute kidney injury who developed symptomatic hypermagnesemia (4.49 mmol/L) and 2:1 second-degree atrioven...
Sleep Deprivation, Cytokine Dysregulation, and the Risk of Cardiac Arrhythmia in Dogs.
BACKGROUND: Sleep deprivation is increasingly recognised as a potent physiological stressor capable of altering immune function and promoting systemic inflammation. Emerging evidence suggests that the...
Electrocardiographic Predictors of Early Recurrence of Atrial Fibrillation After Electrical Cardioversion.
BACKGROUND: Although electrical cardioversion (ECV) effectively restores sinus rhythm in patients with persistent atrial fibrillation (AF), early recurrence after successful ECV remains common in clin...
Withholding Oral Anticoagulation at Discharge and Post-Discharge Stroke and Bleeding Vulnerability in a Predominantly Older Cohort Hospitalized With Acute Heart Failure and Atrial Fibrillation.
AIM: In older adults hospitalized with acute heart failure and atrial fibrillation, bleeding concern often drives withholding of oral anticoagulation at discharge. Whether withholding marks a genuinel...
[Ventricular hypertrophy and pre-excitation: a diagnostic clue to PRKAG2-related cardiomyopathy].
PRKAG2-related cardiomyopathy is a metabolic phenocopy of hypertrophic cardiomyopathy characterized by ventricular hypertrophy, pre-excitation, and supraventricular arrhythmias, frequently leading to ...
Early Cardiotoxic Remodelling Precedes Hepatic Fibrosis and Increases Susceptibility to Lethal Arrhythmias in Wild-Type MASH Mice.
OBJECTIVE: Metabolic dysfunction-associated steatohepatitis (MASH) is increasingly linked to cardiovascular complications; however, the mechanisms underlying the association between hepatic injury and...
Approach to Ventricular Arrhythmias in Heart Failure.
Ventricular arrhythmia remains a challenge in the heart failure population, resulting in significant morbidity and mortality despite modern heart failure therapies. Patients with heart failure who hav...
A 33-Year Old with Wide Complex Tachycardia.
A 33-year-old woman presented to the emergency department (ED) with dizziness and palpitations and was found to be in wide complex tachycardia. EP study the following day showed consistent pre-excitat...
Bachmann Bundle Pacing Combined with ICD in Hypertrophic Cardiomyopathy with Interatrial Conduction Block.
This case presents a 67-year-old man with familial hypertrophic cardiomyopathy, severe heart failure (LVEF 31%, NYHA III), and significant interatrial conduction delay. After ruling out cardiac resync...
Atrial Arrhythmia Following Extra-cardiac Fontan Surgery: Is the Arrhythmia Mechanism Characterized?
We discuss a case of symptomatic atrial arrhythmia in a 31 year old man who had previously undergone extra-cardiac Fontan surgery and a MAZE procedure. Besides the peculiar anatomy that restricted per...