Feasibility of a noninvasive photoplethysmography-based wearable chest patch for cardiac output assessment during exercise compared with thermodilution right heart catheterization.
B, S., A, H., J, H., F, V., A, P., M, K., C, J., & O, M. (2026). Feasibility of a noninvasive photoplethysmography-based wearable chest patch for cardiac output assessment during exercise compared with thermodilution right heart catheterization.. Scientific reports. https://doi.org/10.1038/s41598-026-63092-z
B S, A H, J H, F V, A P, M K, et al. Feasibility of a noninvasive photoplethysmography-based wearable chest patch for cardiac output assessment during exercise compared with thermodilution right heart catheterization.. Scientific reports. 2026; doi: 10.1038/s41598-026-63092-z
B S, A H, J H, et al. Feasibility of a noninvasive photoplethysmography-based wearable chest patch for cardiac output assessment during exercise compared with thermodilution right heart catheterization.[J]. Scientific reports. 2026. DOI: 10.1038/s41598-026-63092-z.
@article{b2026,
author = {Stücker B and Hoss A and Haschemi J and Voß F and Polzin A and Kelm M and Jung C and Maier O},
title = {Feasibility of a noninvasive photoplethysmography-based wearable chest patch for cardiac output assessment during exercise compared with thermodilution right heart catheterization.},
journal = {Scientific reports},
year = {2026},
doi = {10.1038/s41598-026-63092-z},
note = {PMID: 42486909},
}
TY - JOUR AU - Stücker B AU - Hoss A AU - Haschemi J AU - Voß F AU - Polzin A AU - Kelm M AU - Jung C AU - Maier O TI - Feasibility of a noninvasive photoplethysmography-based wearable chest patch for cardiac output assessment during exercise compared with thermodilution right heart catheterization. T2 - Scientific reports PY - 2026 DO - 10.1038/s41598-026-63092-z AN - PMID:42486909 ER -
Hemodynamic monitoring with cardiac output (CO) assessment is usually based on invasive methods that are associated with potential complications. This study compared CO measurements during exercise obtained from a noninvasive photoplethysmography (PPG)-based chest patch monitor with those obtained from invasive thermodilution-based right heart catheterization in patients with heart failure with a preserved ejection fraction (HFpEF). CO was assessed at rest, during passive leg raises, and during 20 Watt (W) of bicycle exercise. Nine patients (67% female) with a mean age of 74.1 ± 12.1 years provided a total of 27 paired measurements. Bland-Altman analysis showed a bias of -0.72 L/min (95% CI - 1.16 to - 0.29) with 95% limits of agreement of - 2.88 to 1.43 L/min and a percentage error of 33%. The CO values obtained by thermodilution and the PPG patch were strongly correlated (r = 0.774; p < 0.001) with a concordance of r = 0.88 (p = 0.002) for the rest-to-20 W change. In this single-center feasibility study, a noninvasive PPG-based chest patch was feasible during exercise right heart catheterization and tracked exercise-induced changes in cardiac output well. Wearable monitoring may offer a low-risk, complementary approach to hemodynamic assessment, but these findings require confirmation in a larger validation cohort.