Permanent Left Ventricular Assist Devices: Long-Term Management and Outcomes.
R, C.D. (2026). Permanent Left Ventricular Assist Devices: Long-Term Management and Outcomes.. Clinics in chest medicine. https://doi.org/10.1016/j.ccm.2026.04.014
R CD. Permanent Left Ventricular Assist Devices: Long-Term Management and Outcomes.. Clinics in chest medicine. 2026; doi: 10.1016/j.ccm.2026.04.014
R CD. Permanent Left Ventricular Assist Devices: Long-Term Management and Outcomes.[J]. Clinics in chest medicine. 2026. DOI: 10.1016/j.ccm.2026.04.014.
@article{r2026,
author = {Crespo-Diaz R},
title = {Permanent Left Ventricular Assist Devices: Long-Term Management and Outcomes.},
journal = {Clinics in chest medicine},
year = {2026},
doi = {10.1016/j.ccm.2026.04.014},
note = {PMID: 42486568},
}
TY - JOUR AU - Crespo-Diaz R TI - Permanent Left Ventricular Assist Devices: Long-Term Management and Outcomes. T2 - Clinics in chest medicine PY - 2026 DO - 10.1016/j.ccm.2026.04.014 AN - PMID:42486568 ER -
This article outlines the historical development, physiologic principles, and contemporary clinical management of durable left ventricular assist devices, with a primary focus on the HeartMate 3 era. An understanding of centrifugal pump physiology, pulsatility index, power, and flow estimation is essential for effective long-term patient management. While major complications such as pump thrombosis and stroke have declined, gastrointestinal bleeding, right ventricular failure, infection, arrhythmias, and outflow graft obstruction remain a significant clinical challenge. Nonetheless, left ventricular assist device therapy as a bridge to transplant, destination therapy, and even recovery are feasible strategies in the context of ongoing donor organ shortages.