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Calcium Channel Blockers in Critical Care Medicine: Current Clinical Applications and Future Investigational Perspectives.

Calcium Channel Blockers in Critical Care Medicine: Current Clinical Applications and Future Investigational Perspectives.

期刊: Medical sciences (Basel, Switzerland) 日期: 2026-04-25 PMID: 42201005 DOI: 10.3390/medsci14020213 浏览: 38
作者: Eraky AM, Mokhtar Y, Grabau G, Khan A, Acharya A, Gadd N, Jarosz M, Premkumar A
AM, E., Y, M., G, G., A, K., A, A., N, G., M, J., & A, P. (2026). Calcium Channel Blockers in Critical Care Medicine: Current Clinical Applications and Future Investigational Perspectives.. Medical sciences (Basel, Switzerland). https://doi.org/10.3390/medsci14020213
AM E, Y M, G G, A K, A A, N G, et al. Calcium Channel Blockers in Critical Care Medicine: Current Clinical Applications and Future Investigational Perspectives.. Medical sciences (Basel, Switzerland). 2026; doi: 10.3390/medsci14020213
AM E, Y M, G G, et al. Calcium Channel Blockers in Critical Care Medicine: Current Clinical Applications and Future Investigational Perspectives.[J]. Medical sciences (Basel, Switzerland). 2026. DOI: 10.3390/medsci14020213.
@article{am2026,
  author = {Eraky AM and Mokhtar Y and Grabau G and Khan A and Acharya A and Gadd N and Jarosz M and Premkumar A},
  title = {Calcium Channel Blockers in Critical Care Medicine: Current Clinical Applications and Future Investigational Perspectives.},
  journal = {Medical sciences (Basel, Switzerland)},
  year = {2026},
  doi = {10.3390/medsci14020213},
  note = {PMID: 42201005},
}
TY  - JOUR
AU  - Eraky AM
AU  - Mokhtar Y
AU  - Grabau G
AU  - Khan A
AU  - Acharya A
AU  - Gadd N
AU  - Jarosz M
AU  - Premkumar A
TI  - Calcium Channel Blockers in Critical Care Medicine: Current Clinical Applications and Future Investigational Perspectives.
T2  - Medical sciences (Basel, Switzerland)
PY  - 2026
DO  - 10.3390/medsci14020213
AN  - PMID:42201005
ER  - 

摘要

Calcium channel blockers (CCBs) are frequently used in the emergency department and intensive care unit for a wide range of critical conditions, including atrial fibrillation, hypertensive emergencies, acute pulmonary edema with sympathetic crashing, pulmonary hypertension, and vasospastic syndromes. However, their toxicity can lead to significant hemodynamic compromise, underscoring the importance of understanding their pharmacologic effects and safety profile. This review summarizes the current applications of CCBs in critically ill patients, evaluates their safety in congestive heart failure, and highlights emerging therapeutic roles and recent advances in the management of CCB toxicity.

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