Patient Selection, Referral Framework and Emerging Therapies in Severe Ischemic Heart Failure: A State-of-the-Art Review.
J, B., A, H., B, H., A, A., & MC, A. (2026). Patient Selection, Referral Framework and Emerging Therapies in Severe Ischemic Heart Failure: A State-of-the-Art Review.. Cardiac electrophysiology clinics. https://doi.org/10.1016/j.ccep.2026.06.012
J B, A H, B H, A A, MC A. Patient Selection, Referral Framework and Emerging Therapies in Severe Ischemic Heart Failure: A State-of-the-Art Review.. Cardiac electrophysiology clinics. 2026; doi: 10.1016/j.ccep.2026.06.012
J B, A H, B H, et al. Patient Selection, Referral Framework and Emerging Therapies in Severe Ischemic Heart Failure: A State-of-the-Art Review.[J]. Cardiac electrophysiology clinics. 2026. DOI: 10.1016/j.ccep.2026.06.012.
@article{j2026,
author = {Basit J and Hanmandlu A and Husainy B and Awad A and Alraies MC},
title = {Patient Selection, Referral Framework and Emerging Therapies in Severe Ischemic Heart Failure: A State-of-the-Art Review.},
journal = {Cardiac electrophysiology clinics},
year = {2026},
doi = {10.1016/j.ccep.2026.06.012},
note = {PMID: 42580799},
}
TY - JOUR AU - Basit J AU - Hanmandlu A AU - Husainy B AU - Awad A AU - Alraies MC TI - Patient Selection, Referral Framework and Emerging Therapies in Severe Ischemic Heart Failure: A State-of-the-Art Review. T2 - Cardiac electrophysiology clinics PY - 2026 DO - 10.1016/j.ccep.2026.06.012 AN - PMID:42580799 ER -
Chronic or severe ischemic heart disease can lead to damaged or infarcted myocardium that can progress to heart failure. When evaluating revascularization, one should consider noninvasive assessments, physiologic testing, angiographic characteristics, and patient comorbidities/functional status. Evaluation for advanced therapies may be needed. Considerations for early referral include repeat heart failure-related hospitalizations despite medical therapy, development of right heart failure, recurrent and refractory ventricular arrhythmias, or intolerance to goal-directed medical therapy. Mechanical circulatory support can act as a bridge to transplant. However, if patients are not candidates for such procedures, initiation of palliative services can improve outcomes and quality of life.