From conceptual emergence to multidisciplinary expansion: a bibliometric and knowledge mapping analysis of cardiovascular-kidney-metabolic syndrome research.
T, L., YJ, X., & QY, Z. (2026). From conceptual emergence to multidisciplinary expansion: a bibliometric and knowledge mapping analysis of cardiovascular-kidney-metabolic syndrome research.. Frontiers in endocrinology. https://doi.org/10.3389/fendo.2026.1895884
T L, YJ X, QY Z. From conceptual emergence to multidisciplinary expansion: a bibliometric and knowledge mapping analysis of cardiovascular-kidney-metabolic syndrome research.. Frontiers in endocrinology. 2026; doi: 10.3389/fendo.2026.1895884
T L, YJ X, QY Z. From conceptual emergence to multidisciplinary expansion: a bibliometric and knowledge mapping analysis of cardiovascular-kidney-metabolic syndrome research.[J]. Frontiers in endocrinology. 2026. DOI: 10.3389/fendo.2026.1895884.
@article{t2026,
author = {Lv T and Xiong YJ and Zhu QY},
title = {From conceptual emergence to multidisciplinary expansion: a bibliometric and knowledge mapping analysis of cardiovascular-kidney-metabolic syndrome research.},
journal = {Frontiers in endocrinology},
year = {2026},
doi = {10.3389/fendo.2026.1895884},
note = {PMID: 42582279},
}
TY - JOUR AU - Lv T AU - Xiong YJ AU - Zhu QY TI - From conceptual emergence to multidisciplinary expansion: a bibliometric and knowledge mapping analysis of cardiovascular-kidney-metabolic syndrome research. T2 - Frontiers in endocrinology PY - 2026 DO - 10.3389/fendo.2026.1895884 AN - PMID:42582279 ER -
BACKGROUND: The concept of cardiovascular-kidney-metabolic (CKM) syndrome has recently been introduced as an integrated framework linking heart, kidney, and metabolic disorders. However, a global overview of the research landscape in this emerging field is still lacking. METHODS: Publications related to CKM published between 2023 and 2025 were retrieved from the Web of Science Core Collection and Scopus. The search strategy incorporated the following terms: TS = ("cardiovascular-kidney-metabolic" OR "cardiovascular kidney metabolic" OR "cardiovascular-kidney-metabolic syndrome" OR "cardiovascular kidney metabolic syndrome" OR "CKM syndrome" OR "CKM health" OR "CKM framework" OR "cardiovascular-kidney-metabolic health"). Bibliometric indicators, including publication volume, authorship patterns, institutional and country contributions, journal distribution, co-citation networks, and keyword burst analysis, were systematically assessed. RESULTS: A total of 1, 854 articles from 665 journals were identified. Annual output surged from 8 in 2023 to 1, 544 in 2025. A total of 8, 359 authors contributed, with an average of 7.95 co-authors per paper, reflecting strong collaborative activity. China and the United States were the most productive countries, with the latter acting as a central node in international collaboration networks. Keyword and citation analyses showed a clear shift from individual risk factors toward integrated cardiometabolic-renal interactions, clinical outcomes, and mortality. Highly cited works mainly addressed the definition, epidemiology, and clinical relevance of CKM. CONCLUSION: Since its introduction in 2023, CKM research has grown rapidly into a collaborative and multidisciplinary field. Future efforts should focus on strengthening international partnerships, advancing mechanistic research, and improving the clinical translation of the CKM framework for risk stratification and prevention.