Impact of Myocardial Bridges on Long-Term Outcomes After Left Anterior Descending Chronic Total Occlusion Recanalization.
Y, G., T, Z., C, G., Y, Z., J, X., H, L., J, C., Y, W., J, Q., & K, D. (2026). Impact of Myocardial Bridges on Long-Term Outcomes After Left Anterior Descending Chronic Total Occlusion Recanalization.. JACC. Cardiovascular interventions. https://doi.org/10.1016/j.jcin.2026.06.020
Y G, T Z, C G, Y Z, J X, H L, et al. Impact of Myocardial Bridges on Long-Term Outcomes After Left Anterior Descending Chronic Total Occlusion Recanalization.. JACC. Cardiovascular interventions. 2026; doi: 10.1016/j.jcin.2026.06.020
Y G, T Z, C G, et al. Impact of Myocardial Bridges on Long-Term Outcomes After Left Anterior Descending Chronic Total Occlusion Recanalization.[J]. JACC. Cardiovascular interventions. 2026. DOI: 10.1016/j.jcin.2026.06.020.
@article{y2026,
author = {Geng Y and Zou T and Guan C and Zhang Y and Xu J and Liu H and Chen J and Wu Y and Qian J and Dou K},
title = {Impact of Myocardial Bridges on Long-Term Outcomes After Left Anterior Descending Chronic Total Occlusion Recanalization.},
journal = {JACC. Cardiovascular interventions},
year = {2026},
doi = {10.1016/j.jcin.2026.06.020},
note = {PMID: 42637293},
}
TY - JOUR AU - Geng Y AU - Zou T AU - Guan C AU - Zhang Y AU - Xu J AU - Liu H AU - Chen J AU - Wu Y AU - Qian J AU - Dou K TI - Impact of Myocardial Bridges on Long-Term Outcomes After Left Anterior Descending Chronic Total Occlusion Recanalization. T2 - JACC. Cardiovascular interventions PY - 2026 DO - 10.1016/j.jcin.2026.06.020 AN - PMID:42637293 ER -
BACKGROUND: A myocardial bridge (MB) is frequently observed after recanalization of a left anterior descending coronary artery (LAD) chronic total occlusion (CTO); however, the long-term prognostic impact of MBs in this specific setting remains controversial. OBJECTIVES: The aim of this study was to determine the impact of MBs on long-term outcomes in patients undergoing percutaneous coronary intervention of LAD CTOs. METHODS: Consecutive patients with LAD CTOs who underwent intravascular ultrasound-guided percutaneous coronary intervention from January 2019 to December 2021 were retrospectively analyzed. The primary endpoint was the 5-year rate of major adverse cardiac events (MACE), a composite of cardiac death, spontaneous myocardial infarction, and ischemia-driven revascularization. RESULTS: Among 685 patients analyzed, MBs were identified in 393 (57.4%) on intravascular ultrasound; stent extension into the bridged segment occurred in 44.3% of these cases (174 of 393). After a median 5-year follow-up, patients with MBs had a higher incidence of MACE compared with those without MBs (16.1% vs 8.9%; P = 0.006), driven primarily by more ischemia-driven revascularization in the MB group (15.1% vs 7.9%; P = 0.004). Stent extension into the MB was associated with a higher rate of MACE compared with sparing the MB (21.4% vs 11.9%; P = 0.0017). MACE rates did not differ between patients with MBs spared from stenting and those without MBs (11.9% vs 8.9%; P = 0.25). CONCLUSIONS: MBs are prevalent after LAD CTO recanalization. Although their presence is associated with adverse outcomes, the risk is driven mainly by stent extension into the bridged segment.