Racial and Ethnic Disparities in Acute Myocarditis Outcomes in the United States.
MF, O., P, L.O., S, V.A., M, D., L, V., J, C., & R, C. (2026). Racial and Ethnic Disparities in Acute Myocarditis Outcomes in the United States.. Clinical cardiology. https://doi.org/10.1002/clc.70460
MF O, P LO, S VA, M D, L V, J C, et al. Racial and Ethnic Disparities in Acute Myocarditis Outcomes in the United States.. Clinical cardiology. 2026; doi: 10.1002/clc.70460
MF O, P LO, S VA, et al. Racial and Ethnic Disparities in Acute Myocarditis Outcomes in the United States.[J]. Clinical cardiology. 2026. DOI: 10.1002/clc.70460.
@article{mf2026,
author = {Osorio MF and Lecompte-Osorio P and Vasquez-Ariza S and Dangl M and Vincent L and Contreras J and Colombo R},
title = {Racial and Ethnic Disparities in Acute Myocarditis Outcomes in the United States.},
journal = {Clinical cardiology},
year = {2026},
doi = {10.1002/clc.70460},
note = {PMID: 42675658},
}
TY - JOUR AU - Osorio MF AU - Lecompte-Osorio P AU - Vasquez-Ariza S AU - Dangl M AU - Vincent L AU - Contreras J AU - Colombo R TI - Racial and Ethnic Disparities in Acute Myocarditis Outcomes in the United States. T2 - Clinical cardiology PY - 2026 DO - 10.1002/clc.70460 AN - PMID:42675658 ER -
BACKGROUND: Racial and ethnic disparities in cardiovascular outcomes are well established, but whether these inequities extend to acute myocarditis remains insufficiently characterized. HYPOTHESIS: Racial and ethnic minority groups hospitalized with acute myocarditis would have higher odds of in-hospital mortality than White patients. METHODS: Using the National Inpatient Sample from 2012 to 2021, we identified adult hospitalizations with a primary diagnosis of acute myocarditis. The primary outcome was all-cause in-hospital mortality. Secondary outcomes included cardiogenic shock, mechanical circulatory support (MCS), cardiac arrest, ventricular tachycardia/fibrillation (VT/VF), acute kidney injury, renal replacement therapy, and stroke. Multivariable logistic regression estimated adjusted odds ratios (aORs). RESULTS: A total of 105 235 weighted hospitalizations were identified. After adjustment, all minority groups had higher odds of in-hospital mortality than White patients: Black (aOR 1.30, 95% CI 1.10-1.55), Hispanic (aOR 1.37, 95% CI 1.14-1.66), Asian/Pacific Islander (aOR 2.07, 95% CI 1.58-2.72), and Other (aOR 1.40, 95% CI 1.07-1.83). Asian/Pacific Islander patients had the highest odds of cardiogenic shock and MCS use. Black patients had higher odds of cardiac arrest and VT/VF. Hispanic patients had higher in-hospital mortality despite lower odds of VT/VF and MCS use. Race and ethnicity by pandemic era interaction for mortality was not significant (p = 0.072). CONCLUSIONS: Among adults hospitalized with acute myocarditis, racial and ethnic minority groups had higher adjusted odds of in-hospital mortality than White patients. Distinct patterns of complications further underscore the need for equitable, attentive, and risk-informed clinical care.