E, N.C., Fatima, R., L, D.D., S, K.S., Debabrata, M., Mandeep, B., Sripal, B., Biykem, B., Khadijah, B., L, C.S., H, d.B.I., H, E.D., S, E.L., P, H.S., S, K.D., Ambar, K., Ildiko, L., C, L.W.C., A, M.C., . . . S, V.S. (2026). 2026 AHA/ACC/ADA/ASN Guideline for the Prevention, Detection, Evaluation, and Management of Cardiovascular-Kidney-Metabolic Syndrome: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.. Circulation. https://doi.org/10.1161/CIR.0000000000001453
E NC, Fatima R, L DD, S KS, Debabrata M, Mandeep B, et al. 2026 AHA/ACC/ADA/ASN Guideline for the Prevention, Detection, Evaluation, and Management of Cardiovascular-Kidney-Metabolic Syndrome: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.. Circulation. 2026; doi: 10.1161/CIR.0000000000001453
E NC, Fatima R, L DD, et al. 2026 AHA/ACC/ADA/ASN Guideline for the Prevention, Detection, Evaluation, and Management of Cardiovascular-Kidney-Metabolic Syndrome: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.[J]. Circulation. 2026. DOI: 10.1161/CIR.0000000000001453.
@article{e2026,
author = {Ndumele Chiadi E and Rodriguez Fatima and Dixon Dave L and Khan Sadiya S and Mukherjee Debabrata and Bajaj Mandeep and Bangalore Sripal and Bozkurt Biykem and Breathett Khadijah and Clarke Shoa L and de Boer Ian H and Ellison David H and Evangelista Lorraine S and Heffron Sean P and Kazi Dhruv S and Kulshreshtha Ambar and Lingvay Ildiko and Low Wang Cecilia C and Mercado Claudia A and Morton John Magaña and Neeland Ian J and Pagidipati Neha and Powell-Wiley Tiffany M and Rangaswami Janani and Rao Goutham and Reza Nosheen and Saeed Anum and St Peter Wendy and Starks J Bradley and Sterling Madeline and Talbot Amy W and Tran Andrew H and Tuttle Katherine R and VanWagner Lisa B and Vest Amanda R and Virani Salim S},
title = {2026 AHA/ACC/ADA/ASN Guideline for the Prevention, Detection, Evaluation, and Management of Cardiovascular-Kidney-Metabolic Syndrome: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.},
journal = {Circulation},
year = {2026},
doi = {10.1161/CIR.0000000000001453},
note = {PMID: 42263157},
}
TY - JOUR AU - Ndumele Chiadi E AU - Rodriguez Fatima AU - Dixon Dave L AU - Khan Sadiya S AU - Mukherjee Debabrata AU - Bajaj Mandeep AU - Bangalore Sripal AU - Bozkurt Biykem AU - Breathett Khadijah AU - Clarke Shoa L AU - de Boer Ian H AU - Ellison David H AU - Evangelista Lorraine S AU - Heffron Sean P AU - Kazi Dhruv S AU - Kulshreshtha Ambar AU - Lingvay Ildiko AU - Low Wang Cecilia C AU - Mercado Claudia A AU - Morton John Magaña AU - Neeland Ian J AU - Pagidipati Neha AU - Powell-Wiley Tiffany M AU - Rangaswami Janani AU - Rao Goutham AU - Reza Nosheen AU - Saeed Anum AU - St Peter Wendy AU - Starks J Bradley AU - Sterling Madeline AU - Talbot Amy W AU - Tran Andrew H AU - Tuttle Katherine R AU - VanWagner Lisa B AU - Vest Amanda R AU - Virani Salim S TI - 2026 AHA/ACC/ADA/ASN Guideline for the Prevention, Detection, Evaluation, and Management of Cardiovascular-Kidney-Metabolic Syndrome: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. T2 - Circulation PY - 2026 DO - 10.1161/CIR.0000000000001453 AN - PMID:42263157 ER -
AIM: The "2026 AHA/ACC/ADA/ASN Guideline for the Prevention, Detection, Evaluation, and Management of Cardiovascular-Kidney-Metabolic Syndrome" retires, replaces, and expands upon the "2013 AHA/ACC/TOS Guideline for the Management of Overweight and Obesity in Adults." The primary intended audience for this guideline is clinicians who care for patients across the spectrum of cardiovascular-kidney-metabolic syndrome, an interrelated condition characterized by the interconnections among metabolic risk factors (including obesity and type 2 diabetes), chronic kidney disease, and cardiovascular disease. METHODS: A comprehensive literature search was conducted from October 29, 2024, to April 14, 2025, to identify clinical studies, systematic reviews and meta-analyses, and other evidence conducted on human subjects that were published since 2015 in English from MEDLINE (through PubMed), EMBASE, the Cochrane Library, the Agency for Healthcare Research and Quality, and other selected databases relevant to this guideline. STRUCTURE: The focus of this clinical practice guideline is to create a living, working document that provides current knowledge in the field of cardiovascular-kidney-metabolic syndrome aimed at all practicing cardiologists, endocrinologists, nephrologists, and primary care and specialty clinicians who manage these patients.