A, C.M., D, B.G., Jay, G., Debabrata, M., Schuyler, J.W., E, B.A., Teresa, C., I, C.A., A, C.L., M, C.S., Mary, C., Kerstin, d.W., M, E.J., C, F.M., B, G.J., Stanislav, H., Hillary, J.C., Sabeeda, K., Daniella, K.D., . . . N, Y.M. (2026). 2026 AHA/ACC/ACCP/ACEP/CHEST/SCAI/SHM/SIR/SVM/SVN Guideline for the Evaluation and Management of Acute Pulmonary Embolism in Adults: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.. Journal of the American College of Cardiology. https://doi.org/10.1016/j.jacc.2025.11.005
A CM, D BG, Jay G, Debabrata M, Schuyler JW, E BA, et al. 2026 AHA/ACC/ACCP/ACEP/CHEST/SCAI/SHM/SIR/SVM/SVN Guideline for the Evaluation and Management of Acute Pulmonary Embolism in Adults: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.. Journal of the American College of Cardiology. 2026; doi: 10.1016/j.jacc.2025.11.005
A CM, D BG, Jay G, et al. 2026 AHA/ACC/ACCP/ACEP/CHEST/SCAI/SHM/SIR/SVM/SVN Guideline for the Evaluation and Management of Acute Pulmonary Embolism in Adults: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.[J]. Journal of the American College of Cardiology. 2026. DOI: 10.1016/j.jacc.2025.11.005.
@article{a2026,
author = {Creager Mark A and Barnes Geoffrey D and Giri Jay and Mukherjee Debabrata and Jones William Schuyler and Burnett Allison E and Carman Teresa and Casanegra Ana I and Castellucci Lana A and Clark Sherrell M and Cushman Mary and de Wit Kerstin and Eaves Jennifer M and Fang Margaret C and Goldberg Joshua B and Henkin Stanislav and Johnston-Cox Hillary and Kadavath Sabeeda and Kadian-Dodov Daniella and Keeling William Brent and Klein Andrew J P and Li Jun and McDaniel Michael C and Moores Lisa K and Piazza Gregory and Prenger Karen S and Pugliese Steven C and Ranade Mona and Rosovsky Rachel P and Russo Farla and Secemsky Eric A and Sista Akhilesh K and Tefera Leben and Weinberg Ido and Westafer Lauren M and Young Michael N},
title = {2026 AHA/ACC/ACCP/ACEP/CHEST/SCAI/SHM/SIR/SVM/SVN Guideline for the Evaluation and Management of Acute Pulmonary Embolism in Adults: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.},
journal = {Journal of the American College of Cardiology},
year = {2026},
doi = {10.1016/j.jacc.2025.11.005},
note = {PMID: 41712898},
}
TY - JOUR AU - Creager Mark A AU - Barnes Geoffrey D AU - Giri Jay AU - Mukherjee Debabrata AU - Jones William Schuyler AU - Burnett Allison E AU - Carman Teresa AU - Casanegra Ana I AU - Castellucci Lana A AU - Clark Sherrell M AU - Cushman Mary AU - de Wit Kerstin AU - Eaves Jennifer M AU - Fang Margaret C AU - Goldberg Joshua B AU - Henkin Stanislav AU - Johnston-Cox Hillary AU - Kadavath Sabeeda AU - Kadian-Dodov Daniella AU - Keeling William Brent AU - Klein Andrew J P AU - Li Jun AU - McDaniel Michael C AU - Moores Lisa K AU - Piazza Gregory AU - Prenger Karen S AU - Pugliese Steven C AU - Ranade Mona AU - Rosovsky Rachel P AU - Russo Farla AU - Secemsky Eric A AU - Sista Akhilesh K AU - Tefera Leben AU - Weinberg Ido AU - Westafer Lauren M AU - Young Michael N TI - 2026 AHA/ACC/ACCP/ACEP/CHEST/SCAI/SHM/SIR/SVM/SVN Guideline for the Evaluation and Management of Acute Pulmonary Embolism in Adults: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. T2 - Journal of the American College of Cardiology PY - 2026 DO - 10.1016/j.jacc.2025.11.005 AN - PMID:41712898 ER -
AIM: The "2026 AHA/ACC/ACCP/ACEP/CHEST/SCAI/SHM/SIR/SVM/SVN Guideline for the Evaluation and Management of Acute Pulmonary Embolism in Adults" is a de novo guideline that provides comprehensive recommendations for the evaluation, management, and follow-up of adult patients (≥18 years of age) with acute pulmonary embolism (acute PE). A key feature of this guideline is the introduction of the AHA/ACC Acute Pulmonary Embolism Clinical Categories, which enhance the precision of severity classification, prognosis assessment, and evidence-based therapeutic decision-making. METHODS: A comprehensive literature search was conducted from February 2024 to October 2024 to identify clinical studies, reviews, and other evidence conducted on human subjects that were published in English from MEDLINE (through PubMed), EMBASE, the Cochrane Library, Agency for Healthcare Research and Quality, and other selected databases relevant to this guideline. Select key studies published until April 2025 were added by the guideline writing committee as appropriate. STRUCTURE: The focus of this clinical practice guideline is an evidence-based and patient-centered approach for acute PE evaluation and management of the adult patient. This guideline encompasses the period from the onset of symptoms through clinical follow-up, focusing on risk outcomes assessment, clinical diagnosis of acute PE, appropriate use of adjunctive cardiovascular testing, and management in both the acute and early post-acute phases of PE. It addresses evidence-based diagnostic and management strategies (including pharmacological therapies, advanced interventional therapies, and in-hospital support) for acute PE and associated outcomes.