Konstantinos, T., Michael, D., Konstantinos, A., Periklis, D., Kyriakos, D., Evangelos, F., Gerasimos, G., Eugenia, G., Michalis, H., Rigas, K., S, K.M., Anastasios, K., Alexandros, K., Dimitrios, K., G, K.K., Efstathios, M., Anargiros, M., Maria, M., K, M.L., . . . Pantelis, S. (2026). Consensus referral pathway for the clinical use of renal denervation in uncontrolled hypertension: a joint statement by the Hellenic Society of Hypertension, the Hellenic Society of Cardiology (WGs "Hypertension and Heart" and "Interventional Cardiology"), the Hellenic Society of Nephrology and the Hellenic Academy of General Practice/Family Medicine and Primary Health Care.. Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese. https://doi.org/10.1016/j.hjc.2025.12.004
Konstantinos T, Michael D, Konstantinos A, Periklis D, Kyriakos D, Evangelos F, et al. Consensus referral pathway for the clinical use of renal denervation in uncontrolled hypertension: a joint statement by the Hellenic Society of Hypertension, the Hellenic Society of Cardiology (WGs "Hypertension and Heart" and "Interventional Cardiology"), the Hellenic Society of Nephrology and the Hellenic Academy of General Practice/Family Medicine and Primary Health Care.. Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese. 2026; doi: 10.1016/j.hjc.2025.12.004
Konstantinos T, Michael D, Konstantinos A, et al. Consensus referral pathway for the clinical use of renal denervation in uncontrolled hypertension: a joint statement by the Hellenic Society of Hypertension, the Hellenic Society of Cardiology (WGs "Hypertension and Heart" and "Interventional Cardiology"), the Hellenic Society of Nephrology and the Hellenic Academy of General Practice/Family Medicine and Primary Health Care.[J]. Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese. 2026. DOI: 10.1016/j.hjc.2025.12.004.
@article{konstantinos2026,
author = {Tsioufis Konstantinos and Doumas Michael and Aznaouridis Konstantinos and Davlouros Periklis and Dimitriadis Kyriakos and Fragkoulis Evangelos and Gavrielatos Gerasimos and Gkaliagkousi Eugenia and Hamilos Michalis and Kalaitzidis Rigas and Kallistratos Manolis S and Kollias Anastasios and Kasiakogias Alexandros and Konstantinidis Dimitrios and Kyriakoulis Konstantinos G and Manios Efstathios and Mariolis Anargiros and Marketou Maria and Michalis Lampros K and Panagoutsos Stylianos and Papachristou Evangelos and Petras Dimitrios and Sanidas Elias and Soulaidopoulos Stergios and Stavropoulos Konstantinos and Stergiou George S and Tatakis Fotis and Thomopoulos Costas and Triantafyllidi Helen and Triantis Georgios and Tsiafoutis Ioannis and Tsigkas Grigorios and Tziakas Dimitrios and Ziakas Antonios and Toutouzas Konstantinos and Sarafidis Pantelis},
title = {Consensus referral pathway for the clinical use of renal denervation in uncontrolled hypertension: a joint statement by the Hellenic Society of Hypertension, the Hellenic Society of Cardiology (WGs "Hypertension and Heart" and "Interventional Cardiology"), the Hellenic Society of Nephrology and the Hellenic Academy of General Practice/Family Medicine and Primary Health Care.},
journal = {Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese},
year = {2026},
doi = {10.1016/j.hjc.2025.12.004},
note = {PMID: 41485762},
}
TY - JOUR AU - Tsioufis Konstantinos AU - Doumas Michael AU - Aznaouridis Konstantinos AU - Davlouros Periklis AU - Dimitriadis Kyriakos AU - Fragkoulis Evangelos AU - Gavrielatos Gerasimos AU - Gkaliagkousi Eugenia AU - Hamilos Michalis AU - Kalaitzidis Rigas AU - Kallistratos Manolis S AU - Kollias Anastasios AU - Kasiakogias Alexandros AU - Konstantinidis Dimitrios AU - Kyriakoulis Konstantinos G AU - Manios Efstathios AU - Mariolis Anargiros AU - Marketou Maria AU - Michalis Lampros K AU - Panagoutsos Stylianos AU - Papachristou Evangelos AU - Petras Dimitrios AU - Sanidas Elias AU - Soulaidopoulos Stergios AU - Stavropoulos Konstantinos AU - Stergiou George S AU - Tatakis Fotis AU - Thomopoulos Costas AU - Triantafyllidi Helen AU - Triantis Georgios AU - Tsiafoutis Ioannis AU - Tsigkas Grigorios AU - Tziakas Dimitrios AU - Ziakas Antonios AU - Toutouzas Konstantinos AU - Sarafidis Pantelis TI - Consensus referral pathway for the clinical use of renal denervation in uncontrolled hypertension: a joint statement by the Hellenic Society of Hypertension, the Hellenic Society of Cardiology (WGs "Hypertension and Heart" and "Interventional Cardiology"), the Hellenic Society of Nephrology and the Hellenic Academy of General Practice/Family Medicine and Primary Health Care. T2 - Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese PY - 2026 DO - 10.1016/j.hjc.2025.12.004 AN - PMID:41485762 ER -
Growing evidence on the long-term efficacy and safety of sympathetic renal denervation (RDN) has established this neuromodulatory interventional therapy as the third therapeutic pillar for hypertension management, alongside lifestyle modification and pharmacotherapy. Accordingly, recent European and American guidelines have upgraded the role of RDN, recommending its consideration as an additional treatment option for selected patients with resistant or uncontrolled hypertension-particularly, for those at high cardiovascular risk-when performed in experienced centers with appropriate training and within a shared decision-making framework that respects patients' preferences. This consensus document, jointly developed by the Hellenic Society of Hypertension (Hellenic Excellence Centers of Hypertension), the Hellenic Society of Cardiology (Working Groups "Hypertension and Heart" and "Interventional Cardiology"), the Hellenic Society of Nephrology, and the Hellenic Academy of General Practice/Family Medicine and Primary Health Care, aims to provide a structured referral pathway for the clinical use of RDN in Greece. The proposed pathway integrates all contemporary therapeutic options in alignment with current hypertension guidelines and takes into account the structure of the Greek health care system. Ongoing and future research regarding antihypertensive therapies, including novel device-based and pharmacological interventions, is anticipated to further refine patient selection, procedural techniques, and long-term strategies to optimize cardiometabolic outcomes.