Pulmonary Arterial Hypertension Associated With Calcitonin Gene-Related Peptide Antagonist Therapy for Migraine: A Case Series.

Calcitonin gene-related peptide (CGRP)-targeted therapies are a recent addition to the migraine field. Monoclonal antibodies became available in 2018 and gepants in 2020, both now widely used for migr...

Zingerone Inhibits ox-LDL-Induced Human Coronary Artery Endothelial Cells Senescence and Apoptosis in Association With Downregulation of HSP90AB1 in Coronary Artery Atherosclerotic Heart Disease.

Zingerone (Zin) exhibits multiple pharmacological properties, including anti-inflammatory, immunomodulatory, anxiolytic, anti-thrombotic, radioprotective, and antimicrobial activities. However, the th...

[The impact of extended travel abroad on patients with heart failure].

Heart failure is a chronic condition whose course can be affected by extended travel. This prospective, open-label study evaluated the impact of stays abroad lasting more than two months on a populati...

[A low-sodium diet for heart failure: necessary or harmful?].

Heart failure is a common condition that leads to a large number of hospitalizations, a high mortality rate, and significant costs for the healthcare system. The symptoms and chronic nature of the dis...

[How patients with heart failure perceive the announcement in a hospital setting].

Heart failure is most often diagnosed in a hospital setting following cardiac decompensation. The delivery of the diagnosis does not occur within a specific framework designed to help patients come to...

Targeting S100A8/A9 Ameliorates Heart Failure with Preserved Ejection Fraction by Modulating TLR4/NF-κB-Mediated Inflammation.

BACKGROUND: Heart failure with preserved ejection fraction (HFpEF) has emerged as one of the most challenging public health issues worldwide, with few effective preventive and therapeutic options avai...

Integrated Blood Inflammatory Ratios and Cerebrospinal Fluid Blood‒Brain Barrier Dysfunction Predict Relapse Risk in Neuromyelitis Optica Spectrum Disorder.

BACKGROUND: Relapse is the primary driver of irreversible disability accumulation in neuromyelitis optica spectrum disorder (NMOSD). Although aquaporin-4 immunoglobulin G (AQP4-IgG) is central to dise...

Single-port extraperitoneal right hemicolectomy with complete mesocolic -A human cadaveric study.

BACKGROUND: Extraperitoneal access strategies have been successfully applied to left-sided colorectal resections, but their application to right-sided colectomy with complete mesocolic excision (CME) ...

Cardiac MRI Monitoring of Myocardial Tissue Changes in a Myocarditis Mouse Model with Histologic Validation.

Purpose To evaluate multiparametric cardiac MRI for assessing myocardial inflammation, fibrosis, and spatiotemporal distribution in autoimmune myocarditis, with histologic reference. Materials and Met...

Lipoprotein(a) and Peripheral Artery Disease as Independent Predictors of Arterial Stiffness in Patients With Hypertension: A Single-Center Cross-Sectional Study.

Carotid-femoral pulse-wave velocity (cfPWV) is a marker of central arterial stiffness and an established predictor of cardiovascular risk in hypertension. Although elevated lipoprotein(a) [Lp(a)] conc...

How ominous are persistent pain and hypertension for uncomplicated Type B aortic dissections?

An initial presentation of severe chest or back pain with uncontrolled hypertension in the absence of cardiac etiology is synonymous with aortic dissection. For aortic dissections that do not involve ...

Respiratory Management for the Infant with Congenital Diaphragmatic Hernia.

Congenital diaphragmatic hernia (CDH) is a complex neonatal condition characterized by pulmonary hypoplasia and pulmonary hypertension, requiring specialized ventilatory management from birth through ...

Plasma p-tau markers, vascular factors, and cognitive decline in the CIMA-Q cohort.

INTRODUCTION: We evaluated associations between phosphorylated au 217 (p-tau217), p-tau181, p-tau231, and vascular risk factors with cognitive outcomes across the Alzheimer's disease (AD) continuum. M...

Association of the TyG Index, Cardiometabolic Index, and Epicardial Adipose Tissue With Coronary Artery Disease.

OBJECTIVES: Metabolic dysregulation and adiposity-related alterations contribute to coronary atherosclerosis, yet the interrelations among cardiometabolic markers and epicardial adipose tissue index (...

[New approaches to nursing practice and the management of heart failure].

Heart failure (HF) affects 2.6 % of adults in France. Against a backdrop of increasingly complex care, the cross-sectional survey presented here-conducted between May and June 2023-analyzes the roles ...

[Post-hospitalization educational programs: complementary or redundant?].

The various educational options offered to patients upon discharge following cardiac decompensation were assessed using a questionnaire as part of this retrospective study. Respondents indicated that ...

[End-of-life care for heart failure: realities in the hospital setting].

Heart failure is a public health issue affecting more than 1 million people in France in 2022, according to Santé publique France. The healthcare teams in the cardiology department at the University H...

[Heart failure: the importance of a structured care pathway and shared expertise].

Chronic heart failure is a major public health issue that requires a multidisciplinary approach based on a coordinated care pathway. The emergence of new nursing specialties, the development of patien...

The Tricuspid Valve in Patients With Transposition of the Great Arteries and a Systemic Right Ventricle: Morphological and Pathophysiological Insights From Three-Dimensional Echocardiography.

AIMS: Tricuspid regurgitation (TR) is related to heart failure (HF) progression in individuals with transposition of the great arteries (TGA) and a systemic right ventricle (sRV). While tricuspid valv...

Hyperlipid-Related Alzheimer's Disease: Potential Role of CircUCK2/miR-24-3p/p38 Axis in Neuronal Damage.

BACKGROUND: Accumulating empirical evidence underscores that hyperlipidemia may fuel the pathological progression of Alzheimer's disease (AD) by triggering inflammatory signaling cascades and promotin...