The complex of gut microbial metabolites and sex hormones in Alzheimer's disease.
Alzheimer's Disease (AD) is a progressive neurodegenerative disorder with a complex pathophysiological mechanism and a marked sex difference in prevalence and disease severity, with women being more a...
Anatomic variations uncommon variant of the callosomarginal artery originating from A1 segment of the anterior cerebral artery with an unruptured aneurysm and distal A1 fenestration.
Some anatomical variations in the A1 segment of the anterior cerebral artery have been reported, but large cortical branches arising from this A1 segment are rare. Herein, we report an unusual case of...
Mural cells protect the adult brain from hemorrhage but do not control the blood-brain barrier in developing zebrafish.
The blood-brain barrier (BBB) protects the brain from circulating metabolites and plays central roles in neurological diseases. Endothelial cells (ECs) of the BBB are enwrapped by mural cells includin...
Early outcomes of redo-TAVI with the SAPIEN 3 platform: the prospective, multicentre ReTAVI registry.
BACKGROUND: Transcatheter aortic valve implantation (TAVI) is increasingly performed in younger and lower-risk patients. Since many of these patients will outlive their transcatheter heart valve (THV)...
TAVI and coronary interventions: indications, technical considerations, and clinical scenarios.
Transcatheter aortic valve implantation (TAVI) has become the preferred treatment for severe aortic stenosis. Nonetheless, interplay between aortic valve disease, transcatheter valve implantation, and...
Early Effect of Transradial Coronary Angiography on Radial Artery Diameter.
OBJECTIVE: To determine whether there is any change in ipsilateral radial artery (RA) diameter following access for transradial coronary angiography and to assess any gender-related association with p...
Prenatal differential diagnosis of pseudo-COA.
BACKGROUND: The prevalence of coarctation of the aorta is 4/10,000, accounting for 8% of congenital heart diseases. Accurate prenatal diagnosis of coarctation of the aorta is still difficult. CASE PRE...
Mechanical heart valve replacement necessitates long-term warfarin anticoagulation to prevent thromboembolic complications, yet achieving adequate anticoagulation control remains challenging. This stu...
The aim of this study was to evaluate real-world rivaroxaban safety and adherence in patients with nonvalvular atrial fibrillation (NVAF). A prospective, observational, cohort, postmarketing study was...
We appreciate the thoughtful commentary by Drs. Dziewierz and Siudak regarding our study comparing tirzepatide versus semaglutide in post-CABG diabetic patients. While we acknowledge the inherent limi...
The evolving cardiovascular burden in Sierra Leone: a 33-year analysis of the Global Burden of Disease study 2023
To quantify trends in stroke, ischaemic heart disease (IHD), and hypertensive heart disease (HHD) in Sierra Leone from 1990 to 2023 using Global Burden of Disease (GBD) Study 2023 estimates. We analyz...
Transcatheter edge-to-edge repair (TEER) has emerged as an important therapy for severe mitral regurgitation. Current guidelines lack evidence-based recommendations for optimal postprocedural antithro...
Correspondence: Life’ s Essential 8 and cardiovascular health: Protective effects on chronic respiratory diseases
Beyond AUC: Questioning the clinical interpretation of “superior” discrimination in cardiovascular health scores
Standard modifiable risk factors (SMuRFs), including hypertension, diabetes, hyperlipidaemia, and smoking, are prevalent among patients undergoing percutaneous coronary intervention (PCI). This study ...
Heart failure-related cardiogenic shock (HF-CS) is now the leading etiology of cardiogenic shock (CS). Advances in temporary mechanical circulatory support (tMCS), particularly microaxial flow pumps (...
Non-Contact Blood Pressure Prediction Using Radar with a Lightweight Temporal Multi-Scale Feature Fusion Network.
Hypertension is a major global health issue, and continuous, convenient blood pressure monitoring is of great significance for early screening and intervention. To address the insufficient exploitatio...
Hydroxysafflor Yellow A Regulates SIRT1-FOXO3-BNIP3 Signaling Pathway to Promote Mitophagy: A Novel Therapeutic Strategy for Myocardial Ischemia-Reperfusion Injury.
BACKGROUND: Hydroxysafflor Yellow A (HSYA), the major bioactive component from Carthamus tinctorius L., exerts significant protective effects against myocardial ischemia-reperfusion injury (MIRI). Mit...