Isolation and Culture of Mouse Brain Microvascular Endothelial Cells.

Brain microvascular endothelial cells (BMECs) are the main cellular component of the blood-brain barrier (BBB) and play a key role in regulating molecular transport and maintaining central nervous sys...

Regional Cardiac Remodeling Signatures Across Atria and Ventricles Revealed by Vein of Marshall and Anterior Interventricular Vein Sampling.

The incidence rate of atrial fibrillation is increasing year by year, which is characterized by time progression, but its mechanism is unknown. Vein of Marshall (VOM), also known as the left atrial ob...

Robot-Assisted Radical Prostatectomy in a Patient with Pre-existing Femoral Crossover Bypass Graft: Multidisciplinary Management and Outcomes.

Robot-assisted radical prostatectomy (RARP) has become the standard surgical treatment for localized clinically significant prostate cancer, yet in patients with pre-existing pelvic vascular grafts, s...

The Ferroptosis-Related Mechanisms of Pentoxifylline in Atrial Fibrillation Treatment.

BACKGROUND: Ferroptosis has been increasingly implicated in the pathophysiology of atrial fibrillation (AF). Pentoxifylline (PTX), a methylxanthine derivative, has shown potential therapeutic benefits...

Endoscopic Minimally Invasive Beating-Heart Tricuspid Valve Surgery Without Jugular Vein Cannulation or Caval Snaring: Clinical Outcomes Using Novel Percutaneous Venous Cannulation.

Background and Objectives: Endoscopic beating-heart tricuspid valve (TV) surgery is increasingly adopted in cardiac surgery due to its association with improved postoperative recovery. Conventional ap...

Geographical and Ethnic Heterogeneity in Genetic Dilated Cardiomyopathies.

Dilated cardiomyopathy (DCM) is the most common cardiomyopathy worldwide. Over the last few decades, significant progress has been made in understanding the genes responsible for DCM. A large number o...

Gamma Oscillations, Sensory Stimulation, and Glymphatic Function: Toward User-Friendly Auditory Interventions for Brain Health in Aging and Neurodegeneration.

The glymphatic system is a brain-wide clearance pathway that facilitates the removal of interstitial solutes, including amyloid-β, and plays a critical role in maintaining brain homeostasis. Impairmen...

Differential Regulation of Protective and Harmful Renin Transcripts by the cAMP/PKA/Ca(2+)-Pathway in Cardiac H9c2 Cells.

Two different renin isoforms are expressed in extrarenal tissues. The classical renin-a has been associated with detrimental effects, whereas renin-b exerts protective effects during glucose starvatio...

The bidirectional genetic causality between immunocyte phenotypes and dilated cardiomyopathy: A bidirectional Mendelian randomization study.

The association between immunocyte phenotypes and dilated cardiomyopathy (DCM) has been explored, however the exact pathogenesis of the relationship between immune cells and DCM is unclear. This bidir...

Inflammation at the crossroads: A bibliometric and integrative review of metabolic-cardiac links in diabetic cardiomyopathy (2004-2024).

BACKGROUND: Diabetic cardiomyopathy (DCM) is a significant diabetes complication, primarily due to persistently high blood sugar and metabolic issues. Chronic low-grade inflammation plays a key role i...

Investigating the mechanisms linking vitamin D to coronary artery disease: A mediating proteomics Mendelian randomisation study.

Coronary artery disease (CAD) is a leading cause of mortality and morbidity globally, with its elevated rates of disability and death posing a significant public health concern. Vitamin D is a crucial...

Risk factors associated with malnutrition in elderly patients with chronic heart failure.

This retrospective observational study aimed to identify clinical determinants of malnutrition in elderly patients with chronic heart failure. Elderly patients (≥65 years) with established chronic hea...

GPER, 8-isoprostaglandin, and tau protein as potential biomarkers in supraventricular tachycardia: An observational study.

Supraventricular tachycardia (SVT) is a common arrhythmic disorder characterized by abnormal electrical impulses arising from supraventricular tissues, most commonly the atria or atrioventricular node...

Association between blood eosinophil count and 28-day mortality among critically ill patients with atrial fibrillation: A retrospective cohort study.

Blood eosinophil count has been associated with prognosis in patients with cardiovascular disease. However, its prognostic value among critically ill patients with atrial fibrillation (AF) remains unc...

Bidirectional Mendelian randomization study on the association between gut microbiota and atrial fibrillation.

Atrial fibrillation (AF) is the most common arrhythmia requiring lifelong treatment. While the gut microbiota has been linked to several cardiovascular diseases, its direct causal relationship with AF...

Knowledge graph visualization and bibliometric analysis of research on coronary artery lesions in Kawasaki disease.

BACKGROUND: Coronary artery lesions (CAL) complicating Kawasaki disease (KD) are a central concern affecting the long-term cardiovascular health of affected children. This study aimed to systematicall...

Analysis of risk factors associated with intimal hyperplasia in arteriovenous fistulas among patients undergoing hemodialysis.

Arteriovenous fistula (AVF) intimal hyperplasia (IH) is a major pathological basis of AVF stenosis and dysfunction in patients undergoing maintenance hemodialysis. This single-center retrospective obs...

Association between aggregate index of systemic inflammation and in-hospital new-onset AF in myocardial infarction with nonobstructive coronary arteries: A retrospective cohort study.

In recent years, with a growing understanding of coronary microvascular dysfunction, myocardial infarction with nonobstructive coronary arteries (MINOCA) has been proposed as a distinct type of myocar...

Comparative performance of stroke risk scores in patients with atrial fibrillation with low stroke risk.

BACKGROUND: Australian guidelines recommend the CHA2DS2-VA (congestive heart failure, hypertension, age ≥75 years (double weight), diabetes mellitus, previous stroke (double weight), vascular disease,...

Diagnosis of postoperative atrial fibrillation using smartwatch monitoring after cardiac surgery: protocol for the FAWATCH single-centre, open-label, randomised controlled trial.

INTRODUCTION: Postoperative atrial fibrillation (POAF) remains the most frequent arrhythmic complication after cardiac surgery, with most episodes occurring after discharge from the intensive care uni...