Experimental Investigation into Bipolar Sealability of Elastin-Rich Tissue.

BACKGROUND: Elastin-rich vessels such as the aorta pose a particular challenge for bipolar tissue sealing due to their high elasticity and low compressibility. It is unclear under which conditions a m...

Effects of Dietary Protein Quantity, Source, and Type on Plasma Lipids and Lipoproteins and Their Roles in Dyslipidemia Management in Humans.

Evidence from clinical trials indicates that dietary protein plays an important and often underappreciated role in lipoprotein lipid metabolism. For this narrative review, literature searches were con...

Reduced Geriatric Nutritional Risk Index Is Associated with Prevalent Diabetes Mellitus and In-Hospital Mortality in Patients Hospitalized with Heart Failure.

Background: Malnutrition is increasingly recognized as an important determinant of prognosis in patients with heart failure (HF). The Geriatric Nutritional Risk Index (GNRI) is a simple nutritional as...

FedHSFV: Federated Learning for Finger Vein Recognition via Hierarchical Decoupling and Subspace Metric.

Finger vein recognition (FVR) has significant potential in biometrics due to its high accuracy and intrinsic liveness detection capabilities. However, the increasingly stringent privacy regulations ha...

Vascular Endothelial Barrier in Salivary Glands: From Physiological Regulation to Pathological Impairment of Secretion.

Although salivary glands are highly vascularized, the microvascular endothelial barrier has only recently emerged as a pivotal determinant of glandular homeostasis and disease. This review synthesizes...

The Immunologic Function of the Choroid Plexus: A Gateway to Immunomodulatory Therapy in Injury Models of the Central Nervous System.

Over time, our understanding of the central nervous system (CNS) as an immunologically privileged site where immune-cell infiltration takes place has changed; research has transformed the dominant vie...

Hunting for an Antigen: Humoral Immunity in Alzheimer's Disease.

Alzheimer's disease (AD) is the leading cause of dementia, affecting millions of individuals on a global scale. A fatal and incurable neurodegenerative disease, AD is defined by various molecular and ...

Sex-Dependent Vascular Responses to Atorvastatin Across Multiple Arterial Beds in a Mouse Model of Marfan Syndrome.

Marfan syndrome (MFS) is characterized by progressive aortic aneurysm formation resulting from mutations in the fibrillin-1 (Fbn1) gene. Although the thoracic aorta is the primary site of pathology, a...

Sex-Based Differences in Atrial Fibrillation: Epidemiology, Prehospital Care, Hospital Management, and Outcomes.

BACKGROUND: Atrial fibrillation is a leading cause of emergency medical services (EMS) use, but sex differences across prehospital, hospital, and postdischarge care remain poorly characterized. METHOD...

Prognostic Value of the Meta-Analysis Global Group in Chronic Heart Failure Risk Score in Patients Undergoing Mitral Valve Transcatheter Edge-to-Edge Repair.

BACKGROUND: The prognostic value of the Meta-Analysis Global Group in Chronic Heart Failure (MAGGIC) score in patients undergoing mitral valve transcatheter edge-to-edge repair (M-TEER) remains unclea...

Diagnostic and Prognostic Utility of Mitral Annular Plane Systolic Excursion: A Systematic Review and Meta-Analysis.

BACKGROUND: Movement of the mitral annulus toward the left ventricular (LV) apex during systole, termed atrioventricular plane displacement or mitral annular plane systolic excursion (MAPSE), was firs...

Endothelial cannabinoid CB1 receptor deficiency reduces shear stress-induced arterial inflammation and lipid uptake.

Peripheral cannabinoid CB1 receptor antagonists that lack central nervous system effects are emerging as promising therapies for metabolic disease, yet the role of endothelial CB1 signaling in atheros...

EAT-Lancet Diet, Plasma Metabolites, and Risk of Peripheral Artery Disease: A Prospective Cohort Study.

BACKGROUND: The Planetary Health Diet Index, developed by the EAT-Lancet Commission, promotes sustainable and healthy eating, yet its association with peripheral artery disease (PAD) remains underexpl...

Metabolic and Safety Outcomes of Statin-Ezetimibe Versus High-Intensity Statin in Older Patients.

BACKGROUND: High-intensity statins are recommended for secondary prevention in atherosclerotic cardiovascular disease (ASCVD), but older adults frequently experience tolerability issues and adverse me...

Clinical characteristics of childhood essential hypertension before, during, and after the COVID-19 pandemic: a single-center retrospective study.

UNLABELLED: To evaluate temporal differences in the clinical characteristics of children diagnosed with essential hypertension before, during, and after the COVID-19 pandemic. This retrospective singl...

Multidimensional correlates of adherence to cardiovascular treatment among patients with multimorbidity from tribal communities in South India: an exploratory cross-sectional study.

INTRODUCTION: Tribal people in India face a growing risk of multimorbidity, primarily from cardiovascular diseases (CVD) due to changing lifestyles and unique socio-cultural and political factors. We ...

Clinical, procedural and patient-reported outcomes of the Ultimaster Nagomi sirolimus-eluting coronary stent in complex percutaneous coronary intervention: the NAGOMI COMPLEX prospective cohort study protocol.

INTRODUCTION: Percutaneous coronary intervention (PCI) has evolved significantly over the past decade with approximately 30% of patients presenting with complex coronary artery disease, posing heighte...

Perceptions and experiences of patients with stable coronary heart disease participating in shared decision-making: a qualitative study in China.

OBJECTIVES: To explore, from the perspective of patients with stable coronary artery disease (SCAD), their perspectives and experiences of shared decision-making (SDM) participation. DESIGN: A descrip...

Association Between Stress Hyperglycemia Ratio and Cardiovascular Outcomes in Patients Who Underwent Complex Percutaneous Coronary Intervention According to Different Glycemic Status.

BACKGROUND: Complex percutaneous coronary intervention is associated with higher risk of long-term worse cardiovascular outcomes than noncomplex procedures. Stress hyperglycemia ratio (SHR), a biomark...

Clinical Outcomes of Complete Revascularization in Acute Myocardial Infarction Patients With High Bleeding Risk and Multivessel Disease.

BACKGROUND: High bleeding risk (HBR) is associated with an increased risk of both ischemic and bleeding events and is known to have a worse prognosis than non-HBR in patients with acute myocardial inf...