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Portopulmonary Hypertension: Current Perspectives.

Portopulmonary Hypertension: Current Perspectives.

期刊: Heart failure clinics 日期: 2026-07-01 PMID: 42309628 DOI: 10.1016/j.hfc.2026.02.008 浏览: 31
作者: John T, Stauber RE, Douschan P
T, J., RE, S., & P, D. (2026). Portopulmonary Hypertension: Current Perspectives.. Heart failure clinics. https://doi.org/10.1016/j.hfc.2026.02.008
T J, RE S, P D. Portopulmonary Hypertension: Current Perspectives.. Heart failure clinics. 2026; doi: 10.1016/j.hfc.2026.02.008
T J, RE S, P D. Portopulmonary Hypertension: Current Perspectives.[J]. Heart failure clinics. 2026. DOI: 10.1016/j.hfc.2026.02.008.
@article{t2026,
  author = {John T and Stauber RE and Douschan P},
  title = {Portopulmonary Hypertension: Current Perspectives.},
  journal = {Heart failure clinics},
  year = {2026},
  doi = {10.1016/j.hfc.2026.02.008},
  note = {PMID: 42309628},
}
TY  - JOUR
AU  - John T
AU  - Stauber RE
AU  - Douschan P
TI  - Portopulmonary Hypertension: Current Perspectives.
T2  - Heart failure clinics
PY  - 2026
DO  - 10.1016/j.hfc.2026.02.008
AN  - PMID:42309628
ER  - 

摘要

Portopulmonary hypertension (PoPH) is a form of pulmonary arterial hypertension in the setting of cirrhotic or noncirrhotic portal hypertension. It is a significant complication affecting approximately 5% of patients with cirrhosis. PoPH contributes to morbidity and mortality of chronic liver disease by significantly increasing right cardiac afterload, ultimately leading to right heart failure and complicating disease management. We review the current literature of PoPH pathophysiology with special focus on cardiopulmonary hemodynamics, clinical presentation, diagnostic challenges, and management strategies. A central illustration should visually capture the summarized information.

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