Hypertensive disorders during pregnancy and cognitive outcomes in children: the ALSPAC study.
OBJECTIVE: This study aimed to examine the associations between hypertensive disorders during pregnancy and intelligence quotient (IQ) in children at the ages of 8 and 16 years. METHODS: Our study sam...
Left ventricular hypertrophy as a predictor of adverse maternal and neonatal outcomes in chronic hypertension in pregnancy: a multicenter study.
OBJECTIVE: The impact of chronic hypertension (CHTN) combined with left ventricular hypertrophy (LVH) on adverse maternal and fetal pregnancy outcomes remains unclear. METHODS: This multicenter retros...
Inter-ankle systolic blood pressure difference is associated with microalbuminuria in non-diabetic hypertension patients: A cross-sectional study from two cohorts.
This cross-sectional study aimed to analyze whether inter-ankle systolic blood pressure difference (sIAND) was associated with different stages of hypertensive renal damage. 1,658 and 831 nondiabetic ...
Does hydrochlorothiazide-associated hyponatremia in hypertensive individuals have a genetic origin?
OBJECTIVE: Hyponatremia is one of the most common electrolyte disorders in clinical practice and is frequently observed following thiazide use. Advanced age and female gender are implicated in the eti...
Gut microbiome drives glycodeoxycholic acid-mediated attenuation of hypertension.
Gut microbiota and bile acids are increasingly recognized to regulate blood pressure, but the mechanisms remain unclear. Takeda G-protein coupled receptor 5 (TGR5) is a major receptor for secondary bi...
Electroacupuncture for essential hypertension: Mechanistic insights, current clinical evidence, and translational challenges.
BACKGROUND: Essential hypertension (EH) remains a leading modifiable risk factor for cardiovascular morbidity and mortality worldwide. Electroacupuncture (EA), combining traditional acupuncture with p...
J‑shaped link of stress hyperglycaemia ratio with in-hospital and 1-year mortality in hypertension patients: based on the MIMIC-IV database.
BACKGROUND: Stress hyperglycaemia ratio (SHR) is notably linked with unfavourable prognoses. Nevertheless, this correlation in hypertension is elusive. This paper uncovered a link of SHR with mortalit...
Utility of serum HMGB1 in chronic obstructive pulmonary disease with pulmonary hypertension: A single-centre analysis.
BACKGROUND: Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) with pulmonary hypertension (PH) worsen outcomes, yet reliable prognostic biomarkers remain lacking. RESEARCH QUESTION...
Blood pressure variability between radial artery and finger is influenced by haemodynamic factors, age and insulin resistance.
BACKGROUND: In clinical practice, blood pressure (BP) is typically assessed using brachial measurements, whereas finger plethysmography is widely used in vascular physiology research. However, agreeme...
Burden of high blood pressure and associated risk for all-cause and cardiovascular mortality among US young adults.
Background: High blood pressure (BP) in young adults is an underrecognised public health issue with potential long-term health consequences, including increased mortality risk. To examine the prevalen...
Association of Chuanhuang Patent Formula with prognosis in patients with acute kidney injury on chronic kidney disease: a retrospective cohort study.
This study evaluated the association of Chuanhuang Patent Formula (CHPF) with short-term renal function parameters and long-term prognosis in patients with acute kidney injury (AKI) on chronic kidney ...
Prevention of new-onset chronic kidney disease with renin-angiotensin system blockers in type 2 diabetes with preserved kidney function.
Renin-angiotensin system (RAS) blockers, including angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs), are known to slow chronic kidney disease (CKD) progression...
Hypertensive disorders in pregnancies with early-onset fetal growth restriction: a retrospective cohort study.
OBJECTIVE: Early onset fetal growth restriction (FGR) shares pathophysiologic origins and may precede the development of Hypertensive Disorder of Pregnancy (HDP). The aim of this study was to evaluate...
Hypertension and gut microbial hydrogenases: a comparison of hydrogen metabolism and etiology.
JOURNAL/mgres/04.03/01612956-202612000-00006/figure1/v/2026-07-23T200825Z/r/image-tiff Hypertension is a prevalent chronic condition and serves as a significant risk factor for numerous cardiovascular...
Prevalence and determinants of alcohol use disorder and its association with adherence to antihypertensive therapy among adult hypertensive patients in a hospital setting, Northwest Ethiopia.
METHODS: A hospital-based cross-sectional study was conducted among hypertensive outpatients at the University of Gondar Comprehensive and Specialized Hospital from January 30 to May 30, 2024. Partici...
IGFBP-1 combined with CHRDL1 in mid-pregnancy serum for predicting fetal growth restriction in late pregnancy among women with gestational hypertension: a prospective nested case-control study.
OBJECTIVE: To investigate the association between mid-pregnancy serum levels of insulin-like growth factor binding protein-1 (IGFBP-1) and chordin-like 1 (CHRDL1) and the occurrence of fetal growth re...
Antihypertensive drugs and arteriovenous fistula flow rates among patients on maintenance hemodialysis in Egypt.
Vascular access dysfunction is a major cause of morbidity among maintenance hemodialysis (HD) patients. Calcium channel blockers (CCBs) may affect vascular remodeling; however, their impact on arterio...
Association between chronotypes and comorbidities in obstructive sleep apnea: The age effect.
BACKGROUND: Obstructive sleep apnoea (OSA) is associated with increased cardiometabolic risk. Although a chronotype, a phenotypic marker of circadian rhythm, appears to influence this relationship, th...
POU2F1 promotes hypertensive cardiac fibrosis by regulating mitochondrial homeostasis through PINK1/Parkin‑dependent mitophagy.
Hypertension‑induced cardiac fibrosis is a major risk factor for heart failure; although disrupted mitochondrial homeostasis has been confirmed to serve a critical role in the pathological process, it...
Emergency department blood pressure elevations frequently occur without documented hypertension diagnosis.
BACKGROUND: High blood pressure readings (HBPRs) are common in emergency department (ED) patients, but the frequency of HBPRs among patients without a documented diagnosis of hypertension (DDxHTN) is ...