Transjugular Transcatheter Tricuspid Valve Implantation of Coronary Stent System for Creating a Rat Tricuspid Regurgitation Model.
X, N., H, X., Q, Z., J, P., X, L., J, C., Q, L., S, D., C, Y., & K, Z. (2026). Transjugular Transcatheter Tricuspid Valve Implantation of Coronary Stent System for Creating a Rat Tricuspid Regurgitation Model.. Journal of cardiovascular translational research. https://doi.org/10.1007/s12265-026-10790-8
X N, H X, Q Z, J P, X L, J C, et al. Transjugular Transcatheter Tricuspid Valve Implantation of Coronary Stent System for Creating a Rat Tricuspid Regurgitation Model.. Journal of cardiovascular translational research. 2026; doi: 10.1007/s12265-026-10790-8
X N, H X, Q Z, et al. Transjugular Transcatheter Tricuspid Valve Implantation of Coronary Stent System for Creating a Rat Tricuspid Regurgitation Model.[J]. Journal of cardiovascular translational research. 2026. DOI: 10.1007/s12265-026-10790-8.
@article{x2026,
author = {Ning X and Xu H and Zhao Q and Pan J and Liu X and Cao J and Li Q and Ding S and Ye C and Zhong K},
title = {Transjugular Transcatheter Tricuspid Valve Implantation of Coronary Stent System for Creating a Rat Tricuspid Regurgitation Model.},
journal = {Journal of cardiovascular translational research},
year = {2026},
doi = {10.1007/s12265-026-10790-8},
note = {PMID: 42234206},
}
TY - JOUR AU - Ning X AU - Xu H AU - Zhao Q AU - Pan J AU - Liu X AU - Cao J AU - Li Q AU - Ding S AU - Ye C AU - Zhong K TI - Transjugular Transcatheter Tricuspid Valve Implantation of Coronary Stent System for Creating a Rat Tricuspid Regurgitation Model. T2 - Journal of cardiovascular translational research PY - 2026 DO - 10.1007/s12265-026-10790-8 AN - PMID:42234206 ER -
We aimed to establish a rat TR model to further investigate the mechanisms of right heart remodeling and organ damage induced by TR. Intervention group rats (n = 6) underwent coronary stent system implantation via transjugular approach. The control group (n = 6) underwent the same procedure, except for coronary stent implantation. All rats survived at 8 weeks follow-up postoperatively. TR occurred immediately after the implantation of coronary stent in the intervention group. The right ventricular fractional area change (FAC) decreased by 33.9% compared with baseline from 0.59 ± 0.11% to 0.39 ± 0.10% (P = 0.005) and the tricuspid annular plane systolic excursion (TAPSE) decreased by 36.8% from 2.42 ± 0.31 mm to 1.53 ± 0.45 mm at 8 weeks (P < 0.001). This animal model would be suitable to further investigate the mechanisms of right ventricular remodeling and other organ damage associated with TR.