[Application prospects of the combined isolated heart perfusion and calcium transient myocardial contraction measurement techniques in cardiovascular protective mechanisms research of acupuncture].
JJ, X., Q, L., TY, J., YX, Z., WX, Y., XC, Y., & JH, G. (2026). [Application prospects of the combined isolated heart perfusion and calcium transient myocardial contraction measurement techniques in cardiovascular protective mechanisms research of acupuncture].. Zhen ci yan jiu = Acupuncture research. https://doi.org/10.13702/j.1000-0607.20250664
JJ X, Q L, TY J, YX Z, WX Y, XC Y, et al. [Application prospects of the combined isolated heart perfusion and calcium transient myocardial contraction measurement techniques in cardiovascular protective mechanisms research of acupuncture].. Zhen ci yan jiu = Acupuncture research. 2026; doi: 10.13702/j.1000-0607.20250664
JJ X, Q L, TY J, et al. [Application prospects of the combined isolated heart perfusion and calcium transient myocardial contraction measurement techniques in cardiovascular protective mechanisms research of acupuncture].[J]. Zhen ci yan jiu = Acupuncture research. 2026. DOI: 10.13702/j.1000-0607.20250664.
@article{jj2026,
author = {Xin JJ and Liu Q and Jiang TY and Zhao YX and Yan WX and Yu XC and Gao JH},
title = {[Application prospects of the combined isolated heart perfusion and calcium transient myocardial contraction measurement techniques in cardiovascular protective mechanisms research of acupuncture].},
journal = {Zhen ci yan jiu = Acupuncture research},
year = {2026},
doi = {10.13702/j.1000-0607.20250664},
note = {PMID: 42343688},
}
TY - JOUR AU - Xin JJ AU - Liu Q AU - Jiang TY AU - Zhao YX AU - Yan WX AU - Yu XC AU - Gao JH TI - [Application prospects of the combined isolated heart perfusion and calcium transient myocardial contraction measurement techniques in cardiovascular protective mechanisms research of acupuncture]. T2 - Zhen ci yan jiu = Acupuncture research PY - 2026 DO - 10.13702/j.1000-0607.20250664 AN - PMID:42343688 ER -
Acupuncture has demonstrated unique potential in the treatment of cardiovascular diseases, yet its further scientific advancement and international recognition still require breakthroughs in mechanism research and evidence strengthening. Isolated heart perfusion technique and calcium transient myocardial contraction measurement technique have provided new perspectives and methods for cardiac research. However, due to experimental limitations, these two techniques have rarely been utilized in acupuncture research. Integrating and applying these two technologies in acupuncture research can enable precise quantification of the multi-target regulatory effects of acupuncture on the autonomic nervous system-calcium cycle at the cellular level, as well as accurate evaluation of the synergistic and/or antagonistic interactions between acupuncture and medication in treating cardiovascular diseases. This integration will provide an effective means to deeply elucidate the calcium-regulation mechanisms underlying the cardiovascular effects of acupuncture. Through detailed analysis of the principles, applications, and advantages of these two technologies, this article further explores their application prospects in the research of cardiovascular modulation mechanism of acupuncture, thereby expanding new fields and directions in basic research of acupuncture. 针灸在心血管疾病治疗中展现出独特潜力，但其科学化、国际化道路仍需突破机制研究、证据强化等瓶颈。离体心脏灌注技术、钙瞬变心肌收缩测量技术为心脏研究提供了新的视角和方法，但由于实验条件的限制，这两项技术在针灸研究中却鲜少得以运用。将这两项技术结合并应用到针灸科研领域，可从细胞层面精准量化针灸对自主神经-钙循环的多靶点调控效应及精准评估针药结合治疗心血管疾病的协同和（或）拮抗作用，为深入揭示针灸对心血管效应的钙调控机制提供有效手段。本文在详细分析这两种技术的原理、应用及优势的基础上，进一步剖析二者在针灸调节心血管效应机制研究方面的应用前景，为针灸基础研究开辟新领域、新方向。.