Early implementation of transradial mechanical thrombectomy in a primary stroke center: a sequential cohort propensity score-matched study.
Y, H. & X, M. (2026). Early implementation of transradial mechanical thrombectomy in a primary stroke center: a sequential cohort propensity score-matched study.. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Soci. https://doi.org/10.1007/s10072-026-09189-9
Y H, X M. Early implementation of transradial mechanical thrombectomy in a primary stroke center: a sequential cohort propensity score-matched study.. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Soci. 2026; doi: 10.1007/s10072-026-09189-9
Y H, X M. Early implementation of transradial mechanical thrombectomy in a primary stroke center: a sequential cohort propensity score-matched study.[J]. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Soci. 2026. DOI: 10.1007/s10072-026-09189-9.
@article{y2026,
author = {Huang Y and Miao X},
title = {Early implementation of transradial mechanical thrombectomy in a primary stroke center: a sequential cohort propensity score-matched study.},
journal = {Neurological sciences : official journal of the Italian Neurological Society and of the Italian Soci},
year = {2026},
doi = {10.1007/s10072-026-09189-9},
note = {PMID: 42366291},
}
TY - JOUR AU - Huang Y AU - Miao X TI - Early implementation of transradial mechanical thrombectomy in a primary stroke center: a sequential cohort propensity score-matched study. T2 - Neurological sciences : official journal of the Italian Neurological Society and of the Italian Soci PY - 2026 DO - 10.1007/s10072-026-09189-9 AN - PMID:42366291 ER -
BACKGROUND: This study assessed the early implementation of transradial access (TRA) for mechanical thrombectomy (MT) in a primary stroke center (PSC) using a retrospective sequential cohort design with propensity score matching. METHODS: We retrospectively analyzed patients with acute large vessel occlusion who underwent MT between January 2022 and December 2024. Patients were assigned to a transfemoral access (TFA) period (January 2022-June 2023) or a TRA period (July 2023-December 2024) based on the timing of formal TRA adoption. Propensity score matching (1:1) was used to reduce baseline imbalance. Primary outcomes were successful recanalization and favorable 90-day functional outcome (modified Rankin Scale 0-2). Secondary outcomes included access-site complications, hospital length of stay, and symptomatic intracranial hemorrhage (sICH). RESULTS: Of 74 eligible patients, 56 were included after matching (28 pairs). Successful recanalization (89.3% vs. 85.7%, P = 1.000) and favorable 90-day outcomes (53.6% vs. 46.4%, P = 0.796) were similar between the TRA and TFA groups. Major vascular complications were rare (0% vs. 3.6%, P = 1.000). Total access-site events were less frequent with TRA, although not statistically significant (3.6% vs. 25.0%, P = 0.052). Hospital stay was shorter during the TRA period (median, 7.0 vs. 10.0 days; P = 0.008). No significant differences were observed in sICH or 90-day mortality. CONCLUSIONS: Early TRA implementation in a PSC appeared feasible, with similar reperfusion and functional outcomes and a favorable safety profile. These findings should be considered exploratory given the small sample size and potential temporal improvements in stroke care.