Noah, P.R., Graham, L., Diez, B.E., Aydin, B., Rebecca, H., Lijiang, M., Nicolas, B., Kelsey, W., D, M.V., Tiit, Ö., Mari, T., Nadja, S., Jessica, P., Michal, M., V, d.K.D.P., J, d.W.M.P., Manuel, M., Lars, M., Karen, R., . . . Mete, C. (2026). Female-Biased VSMC GRNs Predict MYH9 as Regulator of Fibrous Plaque Phenotype.. Circulation research.
Noah PR, Graham L, Diez BE, Aydin B, Rebecca H, Lijiang M, et al. Female-Biased VSMC GRNs Predict MYH9 as Regulator of Fibrous Plaque Phenotype.. Circulation research. 2026; PMID: 41983287
Noah PR, Graham L, Diez BE, et al. Female-Biased VSMC GRNs Predict MYH9 as Regulator of Fibrous Plaque Phenotype.[J]. Circulation research. 2026.
@article{noah2026,
author = {Perry R Noah and Lenert Graham and Benavente Ernest Diez and Bölük Aydin and Hernandez Rebecca and Ma Lijiang and Barbera Nicolas and Watts Kelsey and Mendoza Victor D and Örd Tiit and Taipale Mari and Sachs Nadja and Pauli Jessica and Mokry Michal and de Kleijn Dominique P V and de Winther Menno P J and Mayr Manuel and Maegdefessel Lars and Reue Karen and Kaikkonen Minna U and Björkegren Johan L M and den Ruijter Hester M and Civelek Mete},
title = {Female-Biased VSMC GRNs Predict MYH9 as Regulator of Fibrous Plaque Phenotype.},
journal = {Circulation research},
year = {2026},
note = {PMID: 41983287},
}
TY - JOUR AU - Perry R Noah AU - Lenert Graham AU - Benavente Ernest Diez AU - Bölük Aydin AU - Hernandez Rebecca AU - Ma Lijiang AU - Barbera Nicolas AU - Watts Kelsey AU - Mendoza Victor D AU - Örd Tiit AU - Taipale Mari AU - Sachs Nadja AU - Pauli Jessica AU - Mokry Michal AU - de Kleijn Dominique P V AU - de Winther Menno P J AU - Mayr Manuel AU - Maegdefessel Lars AU - Reue Karen AU - Kaikkonen Minna U AU - Björkegren Johan L M AU - den Ruijter Hester M AU - Civelek Mete TI - Female-Biased VSMC GRNs Predict MYH9 as Regulator of Fibrous Plaque Phenotype. T2 - Circulation research PY - 2026 AN - PMID:41983287 ER -
Atherosclerosis, an inflammatory driver of coronary artery disease, manifests as unstable atheromatous plaques and stable fibrous plaques. Although atheromatous plaques have been extensively studied, fibrous plaques, particularly in women aged <50 years, where erosion contributes significantly to coronary thrombosis, remain less understood. The molecular mechanisms underlying sex differences in plaque biology, including vascular smooth muscle cell contributions, are incompletely defined.