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Evaluation of the lipid accumulation product for MASLD risk stratification in type 2 diabetes: establishing sex-specific thresholds and clinical utility.

期刊: Cardiovascular diabetology 日期: 2026-05-11 PMID: 42116040 浏览: 46
作者: Qu, Li, Tao, Ye, Huang, Chen, Xu, Jiang, Jia, Xie
Qu, Li, Tao, Ye, Huang, Chen, Xu, Jiang, Jia, & Xie (2026). Evaluation of the lipid accumulation product for MASLD risk stratification in type 2 diabetes: establishing sex-specific thresholds and clinical utility.. Cardiovascular diabetology.
Qu, Li, Tao, Ye, Huang, Chen, et al. Evaluation of the lipid accumulation product for MASLD risk stratification in type 2 diabetes: establishing sex-specific thresholds and clinical utility.. Cardiovascular diabetology. 2026; PMID: 42116040
Qu, Li, Tao, et al. Evaluation of the lipid accumulation product for MASLD risk stratification in type 2 diabetes: establishing sex-specific thresholds and clinical utility.[J]. Cardiovascular diabetology. 2026.
@article{qu2026,
  author = {Qu and Li and Tao and Ye and Huang and Chen and Xu and Jiang and Jia and Xie},
  title = {Evaluation of the lipid accumulation product for MASLD risk stratification in type 2 diabetes: establishing sex-specific thresholds and clinical utility.},
  journal = {Cardiovascular diabetology},
  year = {2026},
  note = {PMID: 42116040},
}
TY  - JOUR
AU  - Qu
AU  - Li
AU  - Tao
AU  - Ye
AU  - Huang
AU  - Chen
AU  - Xu
AU  - Jiang
AU  - Jia
AU  - Xie
TI  - Evaluation of the lipid accumulation product for MASLD risk stratification in type 2 diabetes: establishing sex-specific thresholds and clinical utility.
T2  - Cardiovascular diabetology
PY  - 2026
AN  - PMID:42116040
ER  - 

摘要

While visceral adiposity and lipid dysregulation are established drivers of metabolic dysfunction-associated steatotic liver disease (MASLD), the clinical utility of the lipid accumulation product (LAP) for identifying prevalent MASLD in patients with type 2 diabetes mellitus (T2DM) remains insufficiently characterized. This study aimed to characterize the dose-response relationship between LAP and MASLD in T2DM, establish optimal sex-specific diagnostic thresholds, and evaluate its clinical net benefit to guide non-invasive screening.

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