2D-Echocardiographic Estimation of Right Ventricular Volumes Using a Previously Validated Geometric Model Is Associated With Outcomes After Transcatheter Tricuspid Interventions.
MN, A., T, K., J, S., M, B., M, L., V, P., M, N., A, H.F., C, E., & C, B. (2026). 2D-Echocardiographic Estimation of Right Ventricular Volumes Using a Previously Validated Geometric Model Is Associated With Outcomes After Transcatheter Tricuspid Interventions.. Echocardiography (Mount Kisco, N.Y.). https://doi.org/10.1111/echo.70557
MN A, T K, J S, M B, M L, V P, et al. 2D-Echocardiographic Estimation of Right Ventricular Volumes Using a Previously Validated Geometric Model Is Associated With Outcomes After Transcatheter Tricuspid Interventions.. Echocardiography (Mount Kisco, N.Y.). 2026; doi: 10.1111/echo.70557
MN A, T K, J S, et al. 2D-Echocardiographic Estimation of Right Ventricular Volumes Using a Previously Validated Geometric Model Is Associated With Outcomes After Transcatheter Tricuspid Interventions.[J]. Echocardiography (Mount Kisco, N.Y.). 2026. DOI: 10.1111/echo.70557.
@article{mn2026,
author = {Alachkar MN and Kücken T and Schlegl J and Bannehr M and Lichtenauer M and Paar V and Neuß M and Haase-Fielitz A and Edlinger C and Butter C},
title = {2D-Echocardiographic Estimation of Right Ventricular Volumes Using a Previously Validated Geometric Model Is Associated With Outcomes After Transcatheter Tricuspid Interventions.},
journal = {Echocardiography (Mount Kisco, N.Y.)},
year = {2026},
doi = {10.1111/echo.70557},
note = {PMID: 42433112},
}
TY - JOUR AU - Alachkar MN AU - Kücken T AU - Schlegl J AU - Bannehr M AU - Lichtenauer M AU - Paar V AU - Neuß M AU - Haase-Fielitz A AU - Edlinger C AU - Butter C TI - 2D-Echocardiographic Estimation of Right Ventricular Volumes Using a Previously Validated Geometric Model Is Associated With Outcomes After Transcatheter Tricuspid Interventions. T2 - Echocardiography (Mount Kisco, N.Y.) PY - 2026 DO - 10.1111/echo.70557 AN - PMID:42433112 ER -
AIMS: To determine whether a simplified, previously proposed two-dimensional (2D) approach to RV volume assessment can provide adjunctive prognostic information in patients undergoing Transcatheter Tricuspid Valve Interventions (TTVI). METHODS AND RESULTS: In this prospective single-center study, 113 patients undergoing TTVI were included (T-TEER; n = 91, heterotopic caval valve implantation; n = 17, and orthotopic transcatheter tricuspid valve replacement; n = 5). RV end-diastolic and end-systolic volumes were calculated using a previously described 2D-based geometric model. The primary endpoint was a composite of all-cause mortality or rehospitalization for acute decompensated heart failure at 1 year. The primary endpoint occurred in 47 patients (41.6%). In univariable Cox regression analysis, both RVEDVi (HR 1.05 per 10 mL/m2, 95% CI 1.01-1.10, p = 0.03) and RVESVi (HR 1.13 per 10 mL/m2, 95% CI 1.01-1.25, p = 0.03) were associated with adverse outcome. Receiver operating characteristic analysis identified cut-off values of 90 mL/m2 for RVEDVi and 35 mL/m2 for RVESVi. Patients above these thresholds (diastolic, systolic, or both) showed significantly reduced event-free survival (log-rank p < 0.01). In a multivariable Cox regression analysis, RV dilatation showed a trend toward worse outcomes (HR 2.09, 95% CI 0.91-4.80, p = 0.08), whereas the TriScore remained independently associated with outcome (HR 1.30, 95% CI 1.10-1.53, p < 0.01). CONCLUSION: RV volumes derived from a simple 2D echocardiographic model are associated with clinical outcomes and may provide additional information for the assessment of patients undergoing TTVI.