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Atherosclerosis Profiling Reveals BHLHE40 as a Candidate Modulator of VSMC.

期刊: Circulation research 日期: 2026-06-19 PMID: 42125810 浏览: 37
作者: Ibikunle, Garcia, Xue, Kim, Yan, Coronel, Zhu, Cui, Chung, Fries, Sachs, Bauer, Maegdefessel, Li, Tall, Bashore, Reilly
Ibikunle, Garcia, Xue, Kim, Yan, Coronel, Zhu, Cui, Chung, Fries, Sachs, Bauer, Maegdefessel, Li, Tall, Bashore, & Reilly (2026). Atherosclerosis Profiling Reveals BHLHE40 as a Candidate Modulator of VSMC.. Circulation research.
Ibikunle, Garcia, Xue, Kim, Yan, Coronel, et al. Atherosclerosis Profiling Reveals BHLHE40 as a Candidate Modulator of VSMC.. Circulation research. 2026; PMID: 42125810
Ibikunle, Garcia, Xue, et al. Atherosclerosis Profiling Reveals BHLHE40 as a Candidate Modulator of VSMC.[J]. Circulation research. 2026.
@article{ibikunle2026,
  author = {Ibikunle and Garcia and Xue and Kim and Yan and Coronel and Zhu and Cui and Chung and Fries and Sachs and Bauer and Maegdefessel and Li and Tall and Bashore and Reilly},
  title = {Atherosclerosis Profiling Reveals BHLHE40 as a Candidate Modulator of VSMC.},
  journal = {Circulation research},
  year = {2026},
  note = {PMID: 42125810},
}
TY  - JOUR
AU  - Ibikunle
AU  - Garcia
AU  - Xue
AU  - Kim
AU  - Yan
AU  - Coronel
AU  - Zhu
AU  - Cui
AU  - Chung
AU  - Fries
AU  - Sachs
AU  - Bauer
AU  - Maegdefessel
AU  - Li
AU  - Tall
AU  - Bashore
AU  - Reilly
TI  - Atherosclerosis Profiling Reveals BHLHE40 as a Candidate Modulator of VSMC.
T2  - Circulation research
PY  - 2026
AN  - PMID:42125810
ER  - 

摘要

Vascular smooth muscle cells (VSMCs) play a central role in atherosclerosis by undergoing phenotypic modulation from a quiescent, contractile state to a range of synthetic phenotypes, including fibroblast-like, macrophage-like, and lipid-laden foam cell-like states. However, a comprehensive multimodal characterization and understanding of the transcriptional programs driving these transitions remain incomplete.

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