Correlation of Transcutaneous pCO(2) and Capillary pCO(2) in Newborn Patients Depending on Gestational Age: A Secondary Data Analysis.
L, O., C, L.O., A, S., V, P., T, O., & M, S. (2026). Correlation of Transcutaneous pCO(2) and Capillary pCO(2) in Newborn Patients Depending on Gestational Age: A Secondary Data Analysis.. Pediatric pulmonology. https://doi.org/10.1002/ppul.71733
L O, C LO, A S, V P, T O, M S. Correlation of Transcutaneous pCO(2) and Capillary pCO(2) in Newborn Patients Depending on Gestational Age: A Secondary Data Analysis.. Pediatric pulmonology. 2026; doi: 10.1002/ppul.71733
L O, C LO, A S, et al. Correlation of Transcutaneous pCO(2) and Capillary pCO(2) in Newborn Patients Depending on Gestational Age: A Secondary Data Analysis.[J]. Pediatric pulmonology. 2026. DOI: 10.1002/ppul.71733.
@article{l2026,
author = {Olivier L and Lauterbach Oprea C and Stollenwerk A and Pfannschmidt V and Orlikowsky T and Schoberer M},
title = {Correlation of Transcutaneous pCO(2) and Capillary pCO(2) in Newborn Patients Depending on Gestational Age: A Secondary Data Analysis.},
journal = {Pediatric pulmonology},
year = {2026},
doi = {10.1002/ppul.71733},
note = {PMID: 42438310},
}
TY - JOUR AU - Olivier L AU - Lauterbach Oprea C AU - Stollenwerk A AU - Pfannschmidt V AU - Orlikowsky T AU - Schoberer M TI - Correlation of Transcutaneous pCO(2) and Capillary pCO(2) in Newborn Patients Depending on Gestational Age: A Secondary Data Analysis. T2 - Pediatric pulmonology PY - 2026 DO - 10.1002/ppul.71733 AN - PMID:42438310 ER -
INTRODUCTION: Transcutaneous monitoring of CO2 partial pressure (tcpCO2) provides continuous information about the CO2 partial pressure in the blood (pCO2). However, the deviation of tcpCO2 from pCO2 is variable. Our aim was to assess whether this deviation depends on gestational age in the first postnatal week. METHODS: Single-center secondary data cohort study at a Tertiary Care NICU. 116 neonates undergoing tcpCO2 monitoring were included. A linear mixed-effects model was used to analyze the difference between tcpCO2 and capillary pCO2 (ΔpCO2) in the first postnatal week. RESULTS: 926 simultaneous measurements were included. The evaluation of the linear mixed-effects model revealed a significant effect of gestational age on ΔpCO2. Median [interquartile 1; interquartile 3] ΔpCO2 was significantly higher for extremely preterm infants (< 28 weeks) with 7.6 [2.4; 13.9] mmHg compared to 3.1 [-1.0; 6.4] mmHg for very preterm (28-31 + 6 weeks), 0.6 [-4.6; 4.7] mmHg for late preterm (32-36 + 6 weeks) and -0.5 [-4.8; 4.7] mmHg for term infants (≥ 37 weeks). There were no significant differences in ΔpCO2 between patients born at 23 to 25 compared to 26 and 27 completed weeks of gestation. In multivariable analysis, gestational age, early-onset bacterial infection and capillary pCO2 were independently associated with ΔpCO2, whereas birth weight was not. CONCLUSIONS: The gestational age has a significant directed effect on the accuracy of transcutaneous CO2 monitoring in preterm neonates and can-together with other known influence factors-be used to improve the non-invasive pCO2 estimation.