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Drug targets for lipid modification and risk of type 2 diabetes: a cis-Mendelian randomization study.

期刊: Cardiovascular diabetology 日期: 2026-05-14 PMID: 42135799 浏览: 38
作者: Chen, Triatin, Luo, Snieder, Schmidt, Ditmarsch, Kastelein, Dullaart, Kuivenhoven, Thio
Chen, Triatin, Luo, Snieder, Schmidt, Ditmarsch, Kastelein, Dullaart, Kuivenhoven, & Thio (2026). Drug targets for lipid modification and risk of type 2 diabetes: a cis-Mendelian randomization study.. Cardiovascular diabetology.
Chen, Triatin, Luo, Snieder, Schmidt, Ditmarsch, et al. Drug targets for lipid modification and risk of type 2 diabetes: a cis-Mendelian randomization study.. Cardiovascular diabetology. 2026; PMID: 42135799
Chen, Triatin, Luo, et al. Drug targets for lipid modification and risk of type 2 diabetes: a cis-Mendelian randomization study.[J]. Cardiovascular diabetology. 2026.
@article{chen2026,
  author = {Chen and Triatin and Luo and Snieder and Schmidt and Ditmarsch and Kastelein and Dullaart and Kuivenhoven and Thio},
  title = {Drug targets for lipid modification and risk of type 2 diabetes: a cis-Mendelian randomization study.},
  journal = {Cardiovascular diabetology},
  year = {2026},
  note = {PMID: 42135799},
}
TY  - JOUR
AU  - Chen
AU  - Triatin
AU  - Luo
AU  - Snieder
AU  - Schmidt
AU  - Ditmarsch
AU  - Kastelein
AU  - Dullaart
AU  - Kuivenhoven
AU  - Thio
TI  - Drug targets for lipid modification and risk of type 2 diabetes: a cis-Mendelian randomization study.
T2  - Cardiovascular diabetology
PY  - 2026
AN  - PMID:42135799
ER  - 

摘要

Reducing plasma levels of low-density lipoprotein cholesterol (LDL-C) is the cornerstone in the prevention of coronary artery disease (CAD) but may also increase risk of type 2 diabetes (T2D). A comprehensive examination of the genetic evidence of T2D related side-effects of all current lipid-modifying drugs, including those in development, has not yet been performed.

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