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LATS1/2-CD38 Metabolic Rewiring Links Senescence to Intraplaque Thrombosis.

期刊: Circulation research 日期: 2026-07-06 PMID: 42200276 浏览: 58
Anonymous (2026). LATS1/2-CD38 Metabolic Rewiring Links Senescence to Intraplaque Thrombosis.. Circulation research.
Anonymous. LATS1/2-CD38 Metabolic Rewiring Links Senescence to Intraplaque Thrombosis.. Circulation research. 2026; PMID: 42200276
Anonymous. LATS1/2-CD38 Metabolic Rewiring Links Senescence to Intraplaque Thrombosis.[J]. Circulation research. 2026.
@article{paper2026,
  author = {Anonymous},
  title = {LATS1/2-CD38 Metabolic Rewiring Links Senescence to Intraplaque Thrombosis.},
  journal = {Circulation research},
  year = {2026},
  note = {PMID: 42200276},
}
TY  - JOUR
AU  - Anonymous
TI  - LATS1/2-CD38 Metabolic Rewiring Links Senescence to Intraplaque Thrombosis.
T2  - Circulation research
PY  - 2026
AN  - PMID:42200276
ER  - 

摘要

Atherothrombosis, which underlies most acute coronary syndromes and is driven by intraplaque thrombosis, preferentially occurs in regions of disturbed blood flow (d-flow). Although LATS1/2 (large tumor suppressor kinases 1 and 2) are known regulators of endothelial mechanotransduction, the mechanisms by which d-flow connects endothelial senescence, proliferation, and intraplaque thrombosis remain poorly understood.

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