Percutaneous mitral commissurotomy in pregnant women: Immediate and long-term outcomes.
S, B., A, F., S, H., M, A., M, C., F, E.A.B., Z, J., A, B.S., K, E., & B, B. (2026). Percutaneous mitral commissurotomy in pregnant women: Immediate and long-term outcomes.. La Tunisie medicale. https://doi.org/10.62438/tunismed.v104i01.6450
S B, A F, S H, M A, M C, F EAB, et al. Percutaneous mitral commissurotomy in pregnant women: Immediate and long-term outcomes.. La Tunisie medicale. 2026; doi: 10.62438/tunismed.v104i01.6450
S B, A F, S H, et al. Percutaneous mitral commissurotomy in pregnant women: Immediate and long-term outcomes.[J]. La Tunisie medicale. 2026. DOI: 10.62438/tunismed.v104i01.6450.
@article{s2026,
author = {Boudiche S and Farhati A and Haboubi S and Abbassi M and Chedly M and El Ayech Boudiche F and Jebbari Z and Ben Salem A and Ezzaouia K and Besbes B},
title = {Percutaneous mitral commissurotomy in pregnant women: Immediate and long-term outcomes.},
journal = {La Tunisie medicale},
year = {2026},
doi = {10.62438/tunismed.v104i01.6450},
note = {PMID: 42223419},
}
TY - JOUR AU - Boudiche S AU - Farhati A AU - Haboubi S AU - Abbassi M AU - Chedly M AU - El Ayech Boudiche F AU - Jebbari Z AU - Ben Salem A AU - Ezzaouia K AU - Besbes B TI - Percutaneous mitral commissurotomy in pregnant women: Immediate and long-term outcomes. T2 - La Tunisie medicale PY - 2026 DO - 10.62438/tunismed.v104i01.6450 AN - PMID:42223419 ER -
BACKGROUND: Rheumatic mitral stenosis (MS) is prevalent in developing countries. Poorly tolerated during pregnancy, MS is often requiring urgent intervention. OBJECTIVES: This study aimed to evaluate immediate and long-term outcomes after percutaneous (PMC) in pregnant women. METHODS: Observational retrospective study of pregnant women who underwent PMC for severe MS between January 2008 and December 2018. Primary endpoint was procedural success (mitral valve area > 1.5 cm²) without complications. RESULTS: 39 patients. Mean age 34.2±5.1 years. Mean gestational age 28.2±4.9 weeks. PMC was successful in 37 patients (94.8%). There was no maternal mortality. Two procedures failed (1 transseptal puncture failure and 1 severe traumatic mitral regurgitation requiring emergent surgery). If successful, PMC allowed the pursue of pregnancy until full term and vaginal delivery in 36 (92.3%) and 20 (51.3%) patients, respectively. One in utero foetal demise and one neonatal death occurred. At 56.1-month, after exclusion of three patients with prompt surgical valve replacement, there were 7 cases of mitral restenosis (19.4%) with Wilkins score >8, suboptimal result (valve area between 1.5 and 1.8 cm²) and incomplete bicommissural splitting as predictive factors. All babies maintained normal growth and development. CONCLUSION: This study confirmed effectiveness and safety of PMC during pregnancy when performed by an experienced team with a procedural success of 94.8% but at the cost of a restenosis rate of 19.4% at 56.1 months. These were predicted, in addition to Wilkins score, by a suboptimal but accepted immediate result of the procedure, still allowing a step forward.