Endometrial thickness is not a risk factor for hypertensive disorders of pregnancy after IVF treatment in women with male-factor infertility.
N, C., X, G., J, Z., W, S., & X, L. (2026). Endometrial thickness is not a risk factor for hypertensive disorders of pregnancy after IVF treatment in women with male-factor infertility.. Frontiers in endocrinology. https://doi.org/10.3389/fendo.2026.1896764
N C, X G, J Z, W S, X L. Endometrial thickness is not a risk factor for hypertensive disorders of pregnancy after IVF treatment in women with male-factor infertility.. Frontiers in endocrinology. 2026; doi: 10.3389/fendo.2026.1896764
N C, X G, J Z, et al. Endometrial thickness is not a risk factor for hypertensive disorders of pregnancy after IVF treatment in women with male-factor infertility.[J]. Frontiers in endocrinology. 2026. DOI: 10.3389/fendo.2026.1896764.
@article{n2026,
author = {Chen N and Guo X and Zhao J and Shi W and Luo X},
title = {Endometrial thickness is not a risk factor for hypertensive disorders of pregnancy after IVF treatment in women with male-factor infertility.},
journal = {Frontiers in endocrinology},
year = {2026},
doi = {10.3389/fendo.2026.1896764},
note = {PMID: 42539450},
}
TY - JOUR AU - Chen N AU - Guo X AU - Zhao J AU - Shi W AU - Luo X TI - Endometrial thickness is not a risk factor for hypertensive disorders of pregnancy after IVF treatment in women with male-factor infertility. T2 - Frontiers in endocrinology PY - 2026 DO - 10.3389/fendo.2026.1896764 AN - PMID:42539450 ER -
BACKGROUND: The relationship between endometrial thickness and adverse pregnancy outcomes has garnered significant attention from researchers. The aim of this study was to investigates whether endometrial thickness (EMT) is a risk factor for hypertensive disorders of pregnancy (HDP) in women undergoing in vitro fertilization (IVF) due to male-factor infertility. METHODS: This single center retrospective cohort study included 2,536 women aged 20-40 years with male-factor infertility who underwent their first frozen-thawed embryo transfer (FET) and had a singleton live birth. Endometrial thickness was measured via transvaginal ultrasound on the day of embryo transfer, and patients were divided into three groups: ≤8 mm, 8-14 mm, and ≥14 mm. The primary outcome was the incidence of HDP. RESULTS: The overall HDP rate was 3.67%, with no significant difference across EMT groups: 3.97% in the ≤ 8 mm group, 3.74% in the 8-14 mm group, and 3.03% in the ≥ 14 mm group (p=0.760). Older maternal age and higher BMI were significant risk factors for HDP [maternal age (OR 1.10, 95% CI 1.05-1.16, p=0.000) and BMI ≥ 24.0 Kg/m² (OR 2.40, 95% CI 1.10-5.25, p=0.028)], while EMT was not associated with HDP risk. CONCLUSION: Endometrial thickness was not a significant risk factor for HDP in women with male-factor infertility undergoing their first FET.