The Anatomical Landscape of Living Donor Livers: A 101-Case Retrospective Single-Center Study in Indonesia From 2010 to 2025.
ANL, L., TJM, L., Y, M., RA, S., L, S., VMG, M., AA, M., NJ, Z., AB, P., & TA, W. (2026). The Anatomical Landscape of Living Donor Livers: A 101-Case Retrospective Single-Center Study in Indonesia From 2010 to 2025.. Annals of transplantation. https://doi.org/10.12659/AOT.952031
ANL L, TJM L, Y M, RA S, L S, VMG M, et al. The Anatomical Landscape of Living Donor Livers: A 101-Case Retrospective Single-Center Study in Indonesia From 2010 to 2025.. Annals of transplantation. 2026; doi: 10.12659/AOT.952031
ANL L, TJM L, Y M, et al. The Anatomical Landscape of Living Donor Livers: A 101-Case Retrospective Single-Center Study in Indonesia From 2010 to 2025.[J]. Annals of transplantation. 2026. DOI: 10.12659/AOT.952031.
@article{anl2026,
author = {Lalisang ANL and Lalisang TJM and Mazni Y and Syaiful RA and Sihardo L and Marbun VMG and Maharani AA and Zacharia NJ and Putra AB and Wibowo TA},
title = {The Anatomical Landscape of Living Donor Livers: A 101-Case Retrospective Single-Center Study in Indonesia From 2010 to 2025.},
journal = {Annals of transplantation},
year = {2026},
doi = {10.12659/AOT.952031},
note = {PMID: 42548038},
}
TY - JOUR AU - Lalisang ANL AU - Lalisang TJM AU - Mazni Y AU - Syaiful RA AU - Sihardo L AU - Marbun VMG AU - Maharani AA AU - Zacharia NJ AU - Putra AB AU - Wibowo TA TI - The Anatomical Landscape of Living Donor Livers: A 101-Case Retrospective Single-Center Study in Indonesia From 2010 to 2025. T2 - Annals of transplantation PY - 2026 DO - 10.12659/AOT.952031 AN - PMID:42548038 ER -
BACKGROUND Anatomical variations of the hepatic vasculature and bile ducts are critical considerations in living donor liver transplantation (LDLT), yet population-specific data remain limited. This retrospective study aimed to evaluate hepatic artery, portal vein, hepatic vein, and intrahepatic bile duct anatomy in 101 living liver donors at a single center in Indonesia from 2010 to 2025, and to identify donor characteristics associated with these variations. MATERIAL AND METHODS A retrospective review was performed on 101 living liver donors at Cipto Mangunkusumo Hospital, Indonesia (2010-2025). Hepatic artery and portal/hepatic vein anatomy were assessed using computed tomography angiography (CTA), and biliary anatomy using magnetic resonance cholangiopancreatography (MRCP). Variations were classified according to the Michel, Nakamura, and Huang systems. Logistic and multinomial regression analyses evaluated demographic predictors, and linear regression assessed operative time. RESULTS Donors (mean age 31.8±6.2 years; body mass index [BMI] 22.6 kg/m²; 62.5% female) were predominantly Javanese and Sumatran. Canonical anatomy predominated (Michel I 70.8%; Nakamura I 71.9%; Huang A1 59.7%). Sumatran donors demonstrated higher frequencies of hepatic artery and portal vein variants. Increasing age predicted hepatic artery variation (aOR 1.08/year, P=0.046), while BMI influenced portal vein subtypes (P=0.006). No factors affected operative time. CONCLUSIONS Canonical anatomy predominated, with ethnic variations seen in Sumatran donors. Age and BMI predicted vascular variations, while biliary anatomy remained stable. Anatomical variations did not affect operative time, highlighting the importance of preoperative imaging and planning.