[Research progress in myocardial metabolic reprogramming in atrial fibrillation].
XY, Z., YX, X., Y, L., YF, X., YN, L., & XW, Z. (2026). [Research progress in myocardial metabolic reprogramming in atrial fibrillation].. Zhonghua xin xue guan bing za zhi. https://doi.org/10.3760/cma.j.cn112148-20260510-00298
XY Z, YX X, Y L, YF X, YN L, XW Z. [Research progress in myocardial metabolic reprogramming in atrial fibrillation].. Zhonghua xin xue guan bing za zhi. 2026; doi: 10.3760/cma.j.cn112148-20260510-00298
XY Z, YX X, Y L, et al. [Research progress in myocardial metabolic reprogramming in atrial fibrillation].[J]. Zhonghua xin xue guan bing za zhi. 2026. DOI: 10.3760/cma.j.cn112148-20260510-00298.
@article{xy2026,
author = {Zhu XY and Xie YX and Lu Y and Xie YF and Li YN and Zhang XW},
title = {[Research progress in myocardial metabolic reprogramming in atrial fibrillation].},
journal = {Zhonghua xin xue guan bing za zhi},
year = {2026},
doi = {10.3760/cma.j.cn112148-20260510-00298},
note = {PMID: 42595529},
}
TY - JOUR AU - Zhu XY AU - Xie YX AU - Lu Y AU - Xie YF AU - Li YN AU - Zhang XW TI - [Research progress in myocardial metabolic reprogramming in atrial fibrillation]. T2 - Zhonghua xin xue guan bing za zhi PY - 2026 DO - 10.3760/cma.j.cn112148-20260510-00298 AN - PMID:42595529 ER -
心房颤动（房颤）是临床常见的心律失常，其病理机制涉及电重构与代谢调节网络的复杂相互作用。值得注意的是，房颤可引发显著的心肌代谢重编程，这种代谢稳态失衡不仅加速心房结构重构，更是维持颤动波持续传导的关键病理基础。该文系统阐述了房颤中心肌能量代谢障碍、脂质代谢失调、氨基酸代谢紊乱等核心代谢表型特征，以及线粒体功能障碍与氧化应激级联反应在其中的调控作用，并分别介绍不同类型的心脏细胞在房颤中的代谢重编程，从代谢维度揭示房颤的重要分子机制，以期为其精准防治提供新的视角和干预靶点。.