Non-pharmacological interventions for blood pressure management in hypertensive patients: selection of exercise regimens-a systematic review and network meta-analysis.
R, L., X, W., H, L., Z, Y., L, Y., & M, Z. (2026). Non-pharmacological interventions for blood pressure management in hypertensive patients: selection of exercise regimens-a systematic review and network meta-analysis.. Frontiers in endocrinology. https://doi.org/10.3389/fendo.2026.1926728
R L, X W, H L, Z Y, L Y, M Z. Non-pharmacological interventions for blood pressure management in hypertensive patients: selection of exercise regimens-a systematic review and network meta-analysis.. Frontiers in endocrinology. 2026; doi: 10.3389/fendo.2026.1926728
R L, X W, H L, et al. Non-pharmacological interventions for blood pressure management in hypertensive patients: selection of exercise regimens-a systematic review and network meta-analysis.[J]. Frontiers in endocrinology. 2026. DOI: 10.3389/fendo.2026.1926728.
@article{r2026,
author = {Lv R and Wang X and Li H and Yang Z and Ye L and Zhou M},
title = {Non-pharmacological interventions for blood pressure management in hypertensive patients: selection of exercise regimens-a systematic review and network meta-analysis.},
journal = {Frontiers in endocrinology},
year = {2026},
doi = {10.3389/fendo.2026.1926728},
note = {PMID: 42609254},
}
TY - JOUR AU - Lv R AU - Wang X AU - Li H AU - Yang Z AU - Ye L AU - Zhou M TI - Non-pharmacological interventions for blood pressure management in hypertensive patients: selection of exercise regimens-a systematic review and network meta-analysis. T2 - Frontiers in endocrinology PY - 2026 DO - 10.3389/fendo.2026.1926728 AN - PMID:42609254 ER -
OBJECTIVE: To compare and rank the effects of exercise modalities on blood pressure in adults with hypertension. METHODS: We conducted a PRISMA-NMA-compliant systematic review and network meta-analysis. PubMed, the Cochrane Library, and Web of Science were searched through May 24, 2026, for randomized controlled trials of exercise interventions. Random-effects models were used, and interventions were ranked using surface under the cumulative ranking curve values. Risk of bias and evidence certainty were assessed with RoB 2, GRADE, and CINeMA. RESULTS: Thirty trials involving 2,137 participants were included. Compared with standard care, combined training produced the greatest reduction in systolic blood pressure (mean difference [MD], -9.52 mmHg; 95% CI, -13.47 to -5.56) and ranked first. Isometric training and moderate-intensity continuous training also significantly reduced systolic blood pressure. High-intensity continuous training produced the largest reduction in diastolic blood pressure (MD, -7.48 mmHg; 95% CI, -11.54 to -3.43), followed by combined training (MD, -5.84 mmHg; 95% CI, -8.51 to -3.16). No major inconsistency or publication bias was detected. CONCLUSION: Combined training may be most effective for lowering systolic blood pressure, whereas high-intensity continuous training may yield the greatest reduction in diastolic blood pressure. Larger, longer-term trials are needed to confirm these findings. SYSTEMATIC REVIEW REGISTRATION: https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=1432343, identifier CRD420261432343.