Association of 10-year Cardiovascular Risk with Left Ventricular Hypertrophy in a Population of Nigerian Hypertensives.
OO, A. & T, A. (2026). Association of 10-year Cardiovascular Risk with Left Ventricular Hypertrophy in a Population of Nigerian Hypertensives.. The Nigerian postgraduate medical journal. https://doi.org/10.4103/npmj.npmj_580_25
OO A, T A. Association of 10-year Cardiovascular Risk with Left Ventricular Hypertrophy in a Population of Nigerian Hypertensives.. The Nigerian postgraduate medical journal. 2026; doi: 10.4103/npmj.npmj_580_25
OO A, T A. Association of 10-year Cardiovascular Risk with Left Ventricular Hypertrophy in a Population of Nigerian Hypertensives.[J]. The Nigerian postgraduate medical journal. 2026. DOI: 10.4103/npmj.npmj_580_25.
@article{oo2026,
author = {Abiodun OO and Anya T},
title = {Association of 10-year Cardiovascular Risk with Left Ventricular Hypertrophy in a Population of Nigerian Hypertensives.},
journal = {The Nigerian postgraduate medical journal},
year = {2026},
doi = {10.4103/npmj.npmj_580_25},
note = {PMID: 42616978},
}
TY - JOUR AU - Abiodun OO AU - Anya T TI - Association of 10-year Cardiovascular Risk with Left Ventricular Hypertrophy in a Population of Nigerian Hypertensives. T2 - The Nigerian postgraduate medical journal PY - 2026 DO - 10.4103/npmj.npmj_580_25 AN - PMID:42616978 ER -
BACKGROUND: The pooled cohort equation (PCE) for predicting the 10-year risk of atherosclerotic cardiovascular disease (ASCVD) has been utilised in Black populations to predict cardiovascular events. OBJECTIVE: We explored the relationship between PCE ASCVD risk and left ventricular hypertrophy (LVH). MATERIALS AND METHODS: A total of 934 hypertensives from the Federal Medical Centre Abuja Hypertension Registry were analysed for this study. The participants were divided into two groups: those with low ASCVD risk (<7.5%) and those with elevated ASCVD risk (≥7.5%). Electrocardiographic (ECG) LVH was defined by the presence of any of Sokolow-Lyon, Cornell voltage or Gubner-Ungerleider criteria. Echocardiographic LVH was defined as an elevated LV mass index using the linear cube formula of the American College of Cardiology. RESULTS: Participants with elevated ASCVD risk were older (59.2 ± 9.0 years) than those with low ASCVD risk ( P < 0.001). Among participants with elevated ASCVD risk, 299 (42.1%) and 181 (26.3%) had echocardiographic and ECG LVH compared with 75 (32.3%) and 44 (19.6%) in those with low ASCVD risk, respectively ( P < 0.05). Those with elevated ASCVD risk had higher odds of having echocardiographic (odds ratio [OR]: 2.02, 95% confidence interval CI 1.39-2.93) and ECG LVH (OR: 2.00, 95% CI 1.29-3.08) compared to those in the low-risk group ( P < 0.05). CONCLUSION: In this study, an elevated 10-year ASCVD risk was associated with a two-fold increase in the risk of echocardiographic and ECG LVH in a population of Nigerian hypertensives. In resource-limited settings, the use of the ASCVD risk score may facilitate timely referrals for the diagnosis and management of LVH.