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An uncommon side effect of statins: perioral neuropathic symptoms.

An uncommon side effect of statins: perioral neuropathic symptoms.

期刊: BMJ case reports 日期: 2026-08-24 PMID: 42637515 DOI: 10.1136/bcr-2026-274770 浏览: 10
作者: Anis KH, Malaty J
KH, A. & J, M. (2026). An uncommon side effect of statins: perioral neuropathic symptoms.. BMJ case reports. https://doi.org/10.1136/bcr-2026-274770
KH A, J M. An uncommon side effect of statins: perioral neuropathic symptoms.. BMJ case reports. 2026; doi: 10.1136/bcr-2026-274770
KH A, J M. An uncommon side effect of statins: perioral neuropathic symptoms.[J]. BMJ case reports. 2026. DOI: 10.1136/bcr-2026-274770.
@article{kh2026,
  author = {Anis KH and Malaty J},
  title = {An uncommon side effect of statins: perioral neuropathic symptoms.},
  journal = {BMJ case reports},
  year = {2026},
  doi = {10.1136/bcr-2026-274770},
  note = {PMID: 42637515},
}
TY  - JOUR
AU  - Anis KH
AU  - Malaty J
TI  - An uncommon side effect of statins: perioral neuropathic symptoms.
T2  - BMJ case reports
PY  - 2026
DO  - 10.1136/bcr-2026-274770
AN  - PMID:42637515
ER  - 

摘要

A male patient in his 60s, with a history of hypertension and hyperlipidaemia, presented with a sensation of dryness, itchiness, numbness and tingling around his mouth that started after taking atorvastatin, suggesting a small-fibre neuropathy related to statin use. He was prescribed statins based on increased 10-year atherosclerotic cardiovascular disease risk (9.7%) and hyperlipidaemia. This observed side effect subsided when the medication was stopped. Evaluation was conducted to rule out other underlying aetiologies of his symptoms, and it was confirmed that the statins were the cause of the symptoms when two additional repeat statin trials, with both atorvastatin and rosuvastatin, caused similar side effects that promptly resolved within a few days of stopping the medications.

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