Disguised discoloration: Minocycline-induced pigmented cardiac valves.
NL, S., TM, P., S, B., DL, C., & JC, P. (2026). Disguised discoloration: Minocycline-induced pigmented cardiac valves.. Dermatology online journal. https://doi.org/10.25251/0sy2g960
NL S, TM P, S B, DL C, JC P. Disguised discoloration: Minocycline-induced pigmented cardiac valves.. Dermatology online journal. 2026; doi: 10.25251/0sy2g960
NL S, TM P, S B, et al. Disguised discoloration: Minocycline-induced pigmented cardiac valves.[J]. Dermatology online journal. 2026. DOI: 10.25251/0sy2g960.
@article{nl2026,
author = {Salmen NL and Pong TM and Bennett S and Cook DL and Pierson JC},
title = {Disguised discoloration: Minocycline-induced pigmented cardiac valves.},
journal = {Dermatology online journal},
year = {2026},
doi = {10.25251/0sy2g960},
note = {PMID: 42246353},
}
TY - JOUR AU - Salmen NL AU - Pong TM AU - Bennett S AU - Cook DL AU - Pierson JC TI - Disguised discoloration: Minocycline-induced pigmented cardiac valves. T2 - Dermatology online journal PY - 2026 DO - 10.25251/0sy2g960 AN - PMID:42246353 ER -
Tetracyclines are used for a variety of dermatologic conditions, and a known side effect of this therapy is hyperpigmentation in multiple tissues throughout the body. We present the case of a 66-year-old man who underwent aortic valve replacement and was found to have discoloration of the aortic valve leaflets associated with his chronic use of minocycline for rosacea. Minocycline-induced pigmentation of cardiac valves is a documented, although uncommon, phenomenon. There is no evidence linking valve pigmentation to functional valve defects. This case highlights an infrequent manifestation of minocycline-induced pigmentation.