Pilot analysis of protein profile alterations in plasma and aortic tissue of spontaneously hypertensive rats.
A, P., FI, S., A, P., M, G., K, A., & L, T. (2026). Pilot analysis of protein profile alterations in plasma and aortic tissue of spontaneously hypertensive rats.. Acta biochimica Polonica. https://doi.org/10.3389/abp.2026.16571
A P, FI S, A P, M G, K A, L T. Pilot analysis of protein profile alterations in plasma and aortic tissue of spontaneously hypertensive rats.. Acta biochimica Polonica. 2026; doi: 10.3389/abp.2026.16571
A P, FI S, A P, et al. Pilot analysis of protein profile alterations in plasma and aortic tissue of spontaneously hypertensive rats.[J]. Acta biochimica Polonica. 2026. DOI: 10.3389/abp.2026.16571.
@article{a2026,
author = {Papageorgiou A and Sofiou FI and Philippou A and Gkrampovari M and Agiannitopoulos K and Traikov L},
title = {Pilot analysis of protein profile alterations in plasma and aortic tissue of spontaneously hypertensive rats.},
journal = {Acta biochimica Polonica},
year = {2026},
doi = {10.3389/abp.2026.16571},
note = {PMID: 42254743},
}
TY - JOUR AU - Papageorgiou A AU - Sofiou FI AU - Philippou A AU - Gkrampovari M AU - Agiannitopoulos K AU - Traikov L TI - Pilot analysis of protein profile alterations in plasma and aortic tissue of spontaneously hypertensive rats. T2 - Acta biochimica Polonica PY - 2026 DO - 10.3389/abp.2026.16571 AN - PMID:42254743 ER -
The role of proteins in cellular activity has received close attention. Proteome analysis can detect early enough changes in the cell before the appearance of pathological changes. Due to the increasing number of cardiovascular complications, more specifically hypertension in modern life, this experimental pilot study tries to detect early changes in the protein profile in cases with arterial hypertension. In this pilot study, animal models were used, specifically control rats and spontaneously hypertensive rats (SHRs), which are widely used as translational models relevant to human cardiovascular physiology. Using gel electrophoresis (GE) method, we analysed proteomic signature of blood plasma and aorta tissue samples of the animal models.