Association between Cognitive Function and Postoperative Stroke Following Off-Pump Coronary Artery Bypass Grafting.
To investigate the association between cognitive function and postoperative stroke in patients undergoing off-pump coronary artery bypass grafting (CABG). We reviewed patients who underwent cognitive ...
Clinical Significance of High-Sensitivity Cardiac Troponin I and Myoglobin in Patients with Suspected Coronary Microvascular Dysfunction.
To examine distribution of high-sensitivity cardiac troponin I (hs-cTnI) and myoglobin in patients with suspected coronary microvascular dysfunction (CMD). This study included consecutive patients wit...
Extended Dual Antiplatelet Therapy for Multivessel Coronary Artery Disease.
BACKGROUND: Patients with multivessel coronary artery disease often receive 12 months of dual antiplatelet therapy (DAPT) after stenting to reduce the risk of ischemic events. Whether extending DAPT b...
Fabry disease cardiomyopathy: Time for a closer heart rhythm monitoring?
Cardiovascular disease represents the leading cause of death in patients with Anderson-Fabry disease (FD), with sudden cardiac death (SCD) being one of the most frequently reported causes of mortality...
Targeting canonical TGFβ/SMAD3 and ERK1/2 signaling in human valve interstitial cells to modulate immune-fibrotic responses in rheumatic heart disease.
Rheumatic heart disease (RHD) is a chronic sequel of acute rheumatic fever characterized by sustained inflammation, fibrosis, and valve degeneration; however, the underlying processes remain unclear. ...
Global sensitivity analysis through causal discovery for an electromechanical cardiac model.
The rapid development of advanced cardiac imaging and modeling technologies has significantly increased the number of parameters required to accurately characterize cardiac function, thereby improving...
Preoperative CT Assessment of Portal Vein Contact Length Predicts Poor Prognosis in Resectable Pancreatic Head Cancer.
PURPOSE: To investigate whether preoperative computed tomography (CT)-based tumor-portal/superior mesenteric vein (PV/SMV) contact angle and contact length predict pathological venous invasion and ref...
Social Isolation, Loneliness and Subclinical Atherosclerosis.
PURPOSE OF REVIEW: Social isolation and loneliness have emerged as important cardiovascular risk factors, yet the biological mechanisms linking adverse social experiences to cardiovascular disease rem...
Managing a right sinking sinus anatomy during valve-sparing aortic root replacement.
We present a case of an otherwise healthy young male with a 5.0 cm aortic root aneurysm complicated by a thin "sinking" right sinus of Valsalva who underwent a valve-sparing aortic root replacement wi...
Reading between the lines: NLP, symptom documentation, and a new era of cardiovascular prognostication
Blood‒brain barrier permeability assessment: from biomimetic models to multimodal imaging.
The blood‒brain barrier (BBB) is a vital physiological structure that maintains the microenvironmental homeostasis in the central nervous system (CNS). Imbalances in its permeability play a key role i...
Serum Pancreatic Stone Protein Across the Spectrum of Hypertensive Disorders of Pregnancy: Discrimination of Preeclampsia Compared with Conventional Inflammatory Indices.
Background and Objectives: Hypertensive disorders of pregnancy (HDP), including gestational hypertension (GHT) and preeclampsia (PE), share clinical features but differ in pathophysiology and risk pro...
The Role of Long Non-Coding RNAs in the Pathogenesis of Coronary Heart Disease.
Long non-coding RNAs (lncRNAs) constitute an important group of regulatory RNA molecules involved in the control of gene expression at the epigenetic, transcriptional, and post-transcriptional levels....
Interleukin-1β and Interleukin-6 Signaling Differentially Regulate ABC Transporter Activity and Amyloid-β Handling in Primary Porcine Brain Endothelial Cells.
Impaired amyloid-β clearance at the blood-brain barrier (BBB) contributes to Alzheimer's disease (AD), yet the regulation of endothelial transport processes under neuroinflammatory conditions remains ...
Mesenchymal Stem Cells of Epicardial Adipose Tissue Show Differences in Immunophenotype and Osteogenic Potential in Patients with Coronary and Non-Coronary Heart Disease.
Coronary artery calcification (CAC) is a pressing issue in cardiology. Mesenchymal stem cells (MSCs) derived from epicardial adipose tissue (EAT) may serve as a source of osteoblasts in the cardiovasc...
Excess risk for cardiovascular and noncardiovascular comorbidities and multimorbidity among patients with myelodysplastic syndrome: A systematic review and meta-analysis.
The authors performed a systematic review and meta-analysis to estimate the prevalence of comorbidities among patients with myelodysplastic syndrome (MDS) by pooling results from 28 studies and 71,400...
Assessment of markers of primary aldosteronism in systemic sclerosis and their relationships with renal and cardiovascular outcomes.
BACKGROUND: Whether primary aldosteronism (PA), the most common endocrine cause of hypertension (HTN), contributes to HTN and cardiovascular disease burden in systemic sclerosis (SSc) has never been e...
Application of AI in Hypertension Health Education: Scoping Review.
BACKGROUND: Hypertension is a major global health challenge, and effective health education is crucial for improving patients' self-management. Traditional health education approaches are often limite...
The neglected second wound: a qualitative study of patients' experiences of lower limb vascular harvesting for coronary artery bypass grafting.
OBJECTIVE: This study aimed to understand the experiences and feelings of patients undergoing lower limb vein harvesting for coronary artery bypass grafting (CABG). DESIGN: Qualitative, phenomenologic...
[Role of miR-146b-5p in hyperoxia-induced pulmonary vascular remodeling in neonatal rats: mechanisms based on the regulation of ferroptosis].
OBJECTIVES: To investigate the role and mechanism of miR-146b-5p in pulmonary vascular remodeling in neonatal rats with bronchopulmonary dysplasia-associated pulmonary hypertension (BPD-PH) induced by...