The Effect of Semaglutide on Antipsychotic-Induced Weight Gain and Other Metabolic Parameters, among a Cohort of Inpatients.

BACKGROUND AND HYPOTHESIS: Antipsychotic use in severe mental illnesses (SMI) is associated with metabolic dysregulation, including antipsychotic-induced weight gain (AIWG), type 2 diabetes (T2D), and...

SARM1 Regulates BNIP3-Mediated Mitochondrial Quality Control in Diabetic Hearts.

Circulation research

Cardiovascular disease risk factors in young people with diabetes mellitus

The increasing prevalence of diabetes in young adults raises concerns regarding its early cardiometabolic consequences. This study aimed to evaluate cardiac function, renal markers, lipid profile, ins...

Pilot Study Comparing Emergency Physician and Artificial Intelligence-supported Interpretations of Electrocardiograms.

BACKGROUND: Artificial intelligence (AI) tools are increasingly being explored for medical applications; however, their effectiveness in emergency electrocardiogram (ECG) interpretation is under-inves...

[Cardiac Amyloidosis Registry in Santiago, Chile (RAMICAR): Three-Year Follow-Up Results].

UNLABELLED: Cardiac amyloidosis (CA) is characterized by extracellular protein deposition, generating ventricular hypertrophy, heart failure and arrhythmias. The main proteins involved are light chain...

The CHECK-IT Program - Controlling Hypertension in Black Communities through In-Person and Virtual Interventions.

In the United States, Black adults experience disproportionately high rates of hypertension and are nearly twice as likely to die due to a cardiovascular disease-related complication as white adults. ...

Systematic Review: Mineralocorticoid Receptor Antagonists in Heart Failure with Preserved and Mildly Reduced Ejection Fraction.

Heart failure with preserved ejection fraction (HFpEF) or mildly reduced ejection fraction (HFmrEF) is a prevalent condition associated with significant morbidity and mortality, and the benefits of mi...

Complete Recovery of Thyrotoxicosis Cardiomyopathy After Antithyroid and Corticosteroid Therapy: A Case Report.

Thyroid storm (TS) is an extreme hypermetabolic state due to thyrotoxicosis. TS may manifest as cardiovascular symptoms, including atrial fibrillation (AF) (9 - 23%) and heart failure (HF). Dilated ca...

Beyond the Irregular Beat: An Unexpected Case of Raynaud's Phenomenon in a Patient with Atrial Fibrillation.

Raynaud's phenomenon is characterized by episodic vasospasm of the extremities, often triggered by cold or stress. It is a hallmark of systemic sclerosis (SSc) and is frequently associated with pulmon...

Midwall Late Gadolinium Enhancement and Native T1 Elevation in Chronic Myocarditis-Related Dilated Cardiomyopathy: An Evidence-Based Case Report.

BACKGROUND: Cardiovascular magnetic resonance (CMR) is the reference standard for non-invasive myocardial tissue characterization, with proven value in diagnosing and prognosticating myocarditis and n...

Successful Conservative Management of Right Ventricular Perforation Caused by Temporary Pacemaker Placement during Complex Percutaneous Coronary Intervention: A Case Report.

Cardiac tamponade is a critical condition that can result from complications during invasive cardiac procedures. This case report describes a 67-year-old male who developed right ventricular perforati...

[Effect of modified Xiangsha Liujunzi Decoction on adipose tissue browning-Nrg4-liver fatty acid synthesis pathway in rat model of both spleen deficiency and hyperlipidemia].

This study aims to investigate the effect of modified Xiangsha Liujunzi Decoction on adipose tissue browning-neuregulin 4(Nrg4)-liver fatty acid synthesis pathway in the rat model of both spleen defic...

[Zhuyu Pills restore Th1/Th2 balance mediated by CD1d/iNKT cell axis to alleviate disorders of sebum and blood lipid metabolism].

This study aims to explore the pathogenesis of the comorbidity of atherosclerosis(AS) accompanied by seborrhea and the intervention effect of Zhuyu Pills. A mouse model of AS with seborrhea was constr...

[Mechanistic study on regulation of MAPK/NF-κB pathway axis by Jiangzhi Huaban Decoction based on "Qi meridian-blood collateral" theory in improving polarization state of macrophages in atherosclerotic plaques].

This study aimed to investigate the therapeutic effects of Jiangzhi Huaban Decoction(JZHB) on atherosclerosis(AS) model mice and to explore its potential molecular mechanisms using proteomic analysis....

[Bidirectional regulation of ischemic myocardium and atherosclerotic plaque by Qixue Bingzhi Formula: role of angiogenesis in coronary heart disease and related mechanism].

This study investigated the therapeutic effects of the Qixue Bingzhi Formula(QXBZ) on coronary heart disease, focusing on its bidirectional regulation of angiogenesis in myocardial ischemia and athero...

[Mechanism of Dangua Humai Oral Liquid in ameliorating vascular endothelial injury in type 2 diabetes mellitus via HIF-1α].

This study investigated whether Dangua Humai Oral Liquid regulates glycolipid metabolism and vascular endothelial ultrastructure in the rat model of type 2 diabetes mellitus(T2DM) by regulating the ex...

[Discovery and preliminary verification of direct targets of active ingredients of Shuangshen Ningxin Capsules in preventing and treating myocardial ischemia-reperfusion injury].

Based on the magnetic bead "fishing" technology, this study explored the direct targets of the active ingredients of Shuangshen Ningxin Capsules in preventing and treating myocardial ischemi...

Radiofrequency Ablation for Treating Cardiac Arrhythmias in Brazil: Status in the Unified Health System.

BACKGROUND: Cardiac arrhythmias compromise quality of life and are associated with greater morbidity and mortality. Pharmacological treatment generally has limited efficacy and often causes adverse ef...

Five-Year Mortality among Survivors of Coronary Artery Bypass Graft Surgery: A Retrospective Study from a Tertiary Center.

BACKGROUND: Long-term outcome data following Coronary Artery Bypass Graft (CABG) surgery in Brazil remain limited, yet are essential for informing public health policies and guiding clinical practice....

Evaluation of Pulse Wave Velocity using Transthoracic Echocardiography in Children with Bicuspid Aortic Valve.

BACKGROUND: Increased aortic stiffness in patients with bicuspid aortic valve (BAV) may significantly affect morbidity and mortality. OBJECTIVE: We aimed to evaluate aortic elasticity properties and t...